Understanding Gaps in Patient Knowledge of Cervical Cancer Screening
An interview with Jeff Andrews, MD, FRCSC, of BD Life Sciences.
Roflumilast Foam 0.3% Update: Pivotal Phase 3 Trial Outcomes Published in JAMA Dermatology, Arcutis Announces
Publication of the phase 3 ARRECTOR trial findings precede an anticipated PDUFA date of May 22, 2025, for the investigational foam, now under FDA review.
Machine Learning Model Effectively Predicts Depression Risk in Adults with COPD
The model demonstrated 70.63% accuracy for predicting depression, a common comorbidity seen in COPD and one that increases risk for negative outcomes.
Investigational GPR119 Agonist Shows Dual Hepatoprotective and Glycemic Benefits in MASH Patients
EASL 2025. DA-1241 significantly reduced plasma ALT levels, improved systemic inflammatory and fibrosis biomarkers, according to drug developer MetaVia.
Cervical Cancer Screening: What Physicians Can Do To Convince Patients
Study Finds 40% of Research Participants Decline to Learn Results of Alzheimer Disease Biomarker Testing
The new findings are contrary to previous research that found family history of AD increases desire for testing and support the "right not to know."
Foluso Fakorede, MD: Racial Disparities in PAD Amputation Rates
Rates of amputation in Black Americans with peripheral arterial disease are 3-times higher than that of their White counterparts. Dr Fakorede, discusses, here.
Fremanezumab Demonstrates Dual Benefits in Adults with Migraine and Depression
New data from UNITE study suggest fremanezumab was effective in alleviating migraine and comorbid MDD in patients with both conditions.
Stool-Based Testing for Colorectal Cancer Screening is On the Rise: Expert Perspective with Mark Fendrick, MD
The increase in stool-based CRC testing is a logical trend, Hendrick said in an interview, given the convenience plus the 2 million younger adults now eligible for screening.
Identifying HPV Types: Preventing Over Treatment and Under Treatment
Stark Regional Disparities in US Life Expectancy Trends Revealed in Comprehensive Birth Cohort Analysis
Life expectancy increased steadily in the US West and Northeast across the 20th century, but gains were just minimal in Southern states, according to the findings.
Pertussis: A Brief Backgrounder for Primary Care
Cases of whooping cough in the US more than doubled in 2024, and 2 infants have died from the infection. Here is background on the infection and vaccine.
One in 5 US Adults Chooses Against Handwashing, Some Citing it as "Unnecessary," National Survey Finds
While 20% of US adults choose not to wash their hands at appropriate times, nearly half admitted to forgetting to do it, according to a new national survey.
Fecal Microbiota Treatment via Colonoscopy Safe, Effective for Recurrent C. Diff, Study Suggests
DDW 2025. Colonoscopic delivery of fecal therapy prevented recurrent C. diff infection in 95% of participants for 8 weeks, with mild GI adverse events reported by <10%.
BD Onclarity Added to ASCCP Guidelines: What It Means
Multitarget Stool DNA Testing Outperforms FIT/FOBT for Completed Follow-up Colonoscopy in CRC-Vulnerable Populations
DDW 2025. Follow-up colonoscopy after a positive stool-based test was superior among adults aged 45-49 and across diverse populations whose original test was mt-sDNA.
Marschall Runge, MD PhD, Shares Thoughts on the Trajectory of Measles in the US
Measles, declared eradicated in the US 25years ago, has infected 900 Americans and is responsible for 3 deaths of children younger than age 5. How did we get here?
PAD Risk Amplifiers and Screening Strategies: A Talk with Foluso Fakorede, MD
ACP 2025: Dr Fakorede outlines PAD risk amplifiers, polyvascular disease connections, and when to screen using ABI, TBI, or exercise testing in high-risk patients.
AstraZeneca's Triple Inhaled Therapy Meets Primary Endpoints in Phase 3 Trials of Uncontrolled Asthma
The KALOS and LOGOS registration trials in patients with uncontrolled asthma compared the triple fixed dose BGF with dual combination therapy.
The Role of Extended HPV Genotyping In Managing High Risk Patients
Adolescent Hyperglycemia, Insulin Resistance Drive Early Cardiac Structural Changes, Novel Cohort Study Finds
Persistent hyperglycemia between ages 17 and 24 tripled the risk of left ventricular hypertrophy and did so 5 times faster among young women, a new study found.
Peripheral Artery Disease in Primary Care: Expert Insights on Recognition & Risk Factors
ACP 2025: Foluso Fakorede, MD, discusses the importance of recognizing and screening for peripheral artery disease in primary care.
FDA Approves STS101 (Dihydroergotamine) Nasal Powder for Acute Treatment of Migraine
The only approved DHE nasal powder addresses persistent limitations of existing DHE formulations, including liquid nasal sprays and injectables, Satsuma stated.
Mepolizumab Reduces AER in COPD Leading to Emergency Care by 35%: MATINEE Findings Published in NEJM
Mepolizumab also cut annualized exacerbation rates by 21% across the full study cohort and by 31% in a subgroup of participants with chronic bronchitis only.
Burden of Moderate to Severe Atopic Dermatitis Weighs Heavily on Children and Adolescents: Real-World Analysis
The burden of disease was particularly pronounced among adolescents, including significantly greater impact on quality of life and psychosocial interaction.
Signs of Alzheimer Disease vs Age-Related Changes
Occasional trouble finding a word reflects typical age-related brain changes; the changes that cause a person to refer to a watch as a "hand clock" are not the same.
The Toll of Atopic Dermatitis is More than Skin Deep: Q & A with Harvard Child Psychologist Jennifer LeBovidge, PhD
Awareness of the psychological burden of eczema is improving, LeBovidge says, but if clinicians don't address mental health, patients and families will suffer in silence.
High Blood Pressure Advisory in EHR Improves Hypertension Diagnosis, Control Across a Primary Care Network
An EHR advisory that combined alerts to medical assistants with escalation to clinicians increased likelihood of hypertension control by a mean 18% per month.
Loneliness Poses a Critical Barrier to Chronic Care Management
A new survey found that the loneliness linked to a diagnosis of chronic illness saps motivation to seek regular care and almost universally to take medications as prescribed.
Alzheimer Disease in 2025: American Perspectives
US adults want to know if they have Alzheimer disease and early, when treatment may slow it down; they are even willing to risk participation in trials of new drugs. Read more.