Addressing Pediatric Vaccine Hesitancy: Communication Strategies That Work
Effective pediatric vaccine conversations require trust and facts. Family physician Sarah Sams, MD, offers tips for addressing concerns without harming patient relationships.
IV Ketamine NRX-100 Gains FDA Fast Track for Suicidal Depression
The FDA Fast Track designation for NRX-100 (IV, preservative-free ketamine) expands by 10-fold the potential treatment population that seriously considers suicide.
Noninvasive Primary Care Screening Identifies Elevated LVEDP in Nearly 40% of High-Risk Patients
A new study reveals that noninvasive LVEDP screening can enhance heart failure detection and improve patient outcomes in primary care settings.
Back-to-School Vaccine Catch-Up: Strategies From a Family Physician
From EMR reports to targeted nurse visits, Sarah Sams, MD, outlines practical ways PCPs can catch up pediatric vaccinations before school starts.
Does Intranasal Insulin Reach Critical Brain Areas Linked to Memory and Cognition?
Insulin delivered via nasal spray in this first-in-human PET imaging study was observed in 11 key brain areas relevant to cognitive decline, validating a new research avenue.
FDA Accepts Gepotidacin for Priority Review for the Treatment of Uncomplicated Urogenital Gonorrhea
FDA accepts priority review of gepotidacin for uncomplicated urogenital gonorrhea, with phase 3 data showing non-inferiority to standard injectable therapy.
Investigational Oral IL-23 Receptor Antagonist Icotrokinra Improves Skin Clearance in Psoriasis in Phase 3 Study
The oral peptide that selectively targets IL-23 offers a novel approach to quelling the inflammatory process that underlies plaque psoriasis.
Are the GLP-1 Agonists "Forever Drugs?" It's an Open Question, According to Jonathan Bonnet, MD, MPH
The obesity and lifestyle medicine specialist says while research on the question continues, a focus on optimizing nutritional health during treatment is essential.
The TikTok Doc Is In: But Will Your Patient Trust the Diagnosis?
Health information permeates social media platforms exposing Americans to advice, even when they don't want it. The good news? Not many trust it!
How Physicians Can Strengthen Vaccine Confidence During National Immunization Awareness Month
Board-certified family physician Sarah Sams, MD, urges physicians to actively engage their communities to build vaccine confidence and combat misinformation.
Excess Intake of Ultraprocessed Foods is Tied to Higher Cardiometabolic Risk, AHA Advisory Panel Says
The Advisory Panel laid out 4 priority actions for clinicians, policy makers, and industry.
Novel Plasma Assays That Selectively Detect Tau Characteristics Will Refine Clinical Study of Alzheimer Disease
The 2 new plasma assays to enhance Alzheimer’s disease research will support disease staging, predicting disease progression, and monitoring treatment outcome.
The Weekly Dose: Pediatric Vaccine Safety, Atopic Dermatitis, Dementia Risk, and Maternal Depression
Insights on atopic dermatitis treatment preferences, the safety of childhood vaccines, maternal depression’s effect on parenting, and more.
GLP-1 Medications Need a Permanent Place in Primary Care, Says Obesity Medicine Specialist
Jonathan Bonnet, MD, MPH, encourages primary care clinicians to embrace GLP-1 therapy where appropriate to stem multiple risk factors for downstream chronic diseases.
Use of Weight-Loss Drugs Increased Among US Adolescents After AAP Guideline Release
New data shows pediatric pharmacotherapy prescribing rose but remained infrequent, while nutrition counseling rates changed minimally.
Lilly's Oral GLP-1 Agonist Orforglipron Linked to Weight Reduction of 12.4% in Pivotal Phase 3 Trial
The investigational daily oral GLP-1 RA met the primary endpoint for body weight reduction at 72 weeks and also improved a range of cardiovascular risk factors.
Reframing Vaccines as Innovation: A Strategy to Rebuild Patient Trust in Primary Care
Infectious disease physician Amesh Adalja, MD, explains how PCPs can reframe vaccines as health technology to boost confidence and counter hesitancy.
Why Should Primary Care Clinicians Shift to AI-Powered Cognitive Assessment? Experts Explain
Fremanezumab Label Expanded for Treatment of Episodic Migraine in Children Aged 6 to 17 Years
Fremanezumab is now the only CGRP antagonist indicated for prevention of migraine in adults and preventive treatment of episodic migraine in pediatric patients.
11 US Vaccine Policy Updates: How Will They Affect Your Practice?
Since his Senate approval as head of HHS in February, RFK Jr has enacted and/or proposed seismic changes to US vaccine policy that will impact your daily care of patients.
Investigational Antidepressant BH-200 Shows Benefit in Phase 2b Trial for MDD
The vasopressin V1b antagonist reduced depressive symptoms, with greater effects in genetically-selected patients using a precision psychiatry approach.
Nearly 17 Million US Youth Found Eligible for GLP-1 RA Therapy and Most Because of Obesity
An NHANES-based cross sectional study found that 1 in 5 of the treatment-eligible youth lacked adequate insurance and one-third had no routine place for health care.
Primary Care Needs the Right Tools to Identify MCI Early, Says Rodney Swenson, PhD
If primary care clinicians are to meet the cognitive screening demands that are growing with an aging population, they need the sharpest tools in the box, this expert says.
The Biggest Threat to Vaccine Confidence in the US: An Expert Discussion
Amesh Adalja, MD, urges physicians to use their trusted position to counter widespread vaccine misinformation and strengthen patient confidence in immunization.
Cognition is The Next Vital Sign: An Interview with David J. Libon, PhD
A cognitive health assessment will soon be as routine as taking blood pressure or pulse oximetry, says neurocognitive researcher David J. Libon, PhD. He talks more about that future.
When Guidelines Diverge: Navigating Vaccine Recommendations in 2025
Amesh Adalja, MD, advises physicians turn to specialty societies for evidence-based, reliable recommendations this respiratory virus season.
Vertex VX-993 Misses Primary Endpoint in Mid-Stage Trial, Ending Investigation for Acute Pain
The NaV1.8 ion channel inhibitor was planned as a follow-up to the company's first nonopioid for acute pain, suzetrigine, approved by the FDA in January 2025.
One-Third of US Adults Aged 45-49 Were Up-to-Date on Colorectal Cancer Screening in 2023
New data show up-to-date CRC screening rose from 20.8% in 2019 to 33.7% in 2023, with gains driven by stool testing and colonoscopy.
FIT Tests, Direct Mailed, Increase Initiation of CRC Screening in Adults Aged 45 to 49
For initiating colorectal cancer screening in average-risk young adults, a default mailed outreach strategy outperformed 3 active choice options in a randomized study.
In Testing for Cognitive Decline, It May Not Be What the Patient Says, But How It's Said That Matters
Acoustic variables, like shimmer and jitter, that are typically undetectable in human speech can be detected with tablet technology and serve as biomarkers for mental acuity.
