Expert Perspectives 2024: Biologics for Management of COPD with MeiLan K Han, MD, MS
The GOLD report committee member highlights advances in knowledge of COPD phenotypes and the new role for biologic medications in this year's video series.
The Biggest Challenge with COVID-19 Right Now: An Interview with NFID Medical Director Robert Hopkins, Jr, MD
Hopkins, of the National Foundation for Infectious Diseases, is frustrated by the diminished societal response to the virus' circulation including ongoing low vaccination rates.
Safety of Moderna’s mRNA RSV Vaccine for Infants Heads Dec 12 VRBPAC Meeting Agenda
Moderna paused clinical research on the pediatric shot indefinitely in September after reports in July of severe adverse reactions in infants aged 5 to 8 months.
Atogepant Improves QoL, Function in Adults with Chronic, Episodic, Treatment-Resistant Migraine
An analysis of patient reported outcome measures from 3 pivotal phase 3 RCTs of atogepant 60 mg demonstrates efficacy across functional domains as well as for migraine prevention.
10 More Can't Miss Doctor Gifts Worth Giving...or Having
An MDF stethoscope with leopard print tubing? A digital highlighter/scanner that translates and talks back? Check out these and 8 more uncommon gifts for health care professionals.
New COVID-19 Vaccination Guidance for Older Adults & High-Risk Groups: A Conversation with NFID Medical Director Robert Hopkins, Jr, MD
Guidance from the Advisory Committee on Immunization Practices on best practices for COVID-19 vaccination continues to evolve, Hopkins explained.
Americans Rate US Health Care at All-Time Low: A Gallup Survey Snapshot
Americans' rating of the quality of health care available in the US has hit its lowest in 24 years, according to a new Gallup survey; here's what they think.
NFID Medical Director Highlights ACIP Rationale for Lowering Age for Pneumococcal Vaccination
Under risk-based guidelines, less than 30% of eligible adults are vaccinated against pneumococcal disease, said Robert Hopkins, Jr, MD. More details, here.
10 Questions on Holiday Spirits
How does alcohol figure in to American holiday celebrations? We checked with Alcohol.org for this quiz. Are answers what you expect?
Dupilumab Effective in Young Children with Atopic Dermatitis, Comorbid T2 Inflammatory Disease
Dupilumab significantly reduced signs and symptoms of AD in children aged 6 months to 5 years with concomitant asthma, allergic rhinitis, and food allergy.
Fremanezumab Safe and Effective for Prevention of Episodic Migraine in Children: Phase 3 Data Announced
The CGRP inhibitor fremanezumab reduced both monthly migraine and monthly headache days among children aged 6 to 17 years with a favorable safety profile.
Tirzepatide Bests Semaglutide for Weight Loss by 47% in Head-to-Head Trial
"Twincretin" tirzepatide-treated participants in SURMOUNT-5 lost a mean 50 lbs vs an average loss of 33 lbs for those treated with semaglutide.
Pearls for Primary Care: How to Talk About Agitation in Alzheimer Disease with Caregivers
A geriatric psychiatrist talks about the importance of asking caregivers about behavior in order to understand and treat agitation in Alzheimer dementia.
NDA Submission for Anaphylm (Epinephrine) Sublingual Film on Track for Q1 2025, Company Says
Aquestive Therapeutics announced positive feedback from the FDA this week that keeps NDA planning for the novel epinephrine product on solid ground.
10 Can't Miss Doctor Gifts Worth Giving in 2024
Holiday health care gift-giving season is here and we've done some window shopping for our primary care readers. Take a breath and scroll through our top 10 suggestions for 2024.
"Be Vigilant About Risk Factors for COPD, Aggressive with Questions About Symptoms," Expert Advises Primary Care
COPD expert MeiLan K Han, MD, MS, says that in the absence of a definitive single tool to assess for COPD, probing patients for risk factors and symptoms is essential.
Online Misinformation on UTIs, ASB is Common and Dangerous: New Research
At least 1 accurate UTI symptom was found on most of the 331 websites reviewed, but nearly all (80%) included at least 1 inaccurate or misleading one.
2025 GOLD Report on COPD Addresses Cardiovascular Risk in New Section: MeiLan Han, MD, MS, Highlights Rationale
Cardiovascular comorbidities in adults with COPD are linked to poor outcomes including reduced QoL, increased hospitalizations, and greater risk of mortality, Han explains.
Dupilumab, Ensifentrine Added to 2025 GOLD Guidelines for COPD: Expert Parses Recommendations
Professor MeiLan Han, MD, MS, details inclusion of the 2 new medications and how the additions reflect a focus on disease heterogeneity and precision medicine in in COPD.
More than Half of US Adults May Be Eligible for Semaglutide Therapy, Accordng to New Estimates
Millions of US adults could benefit from semaglutide treatment for diabetes, obesity, and/or CV disease but insurance isn't guaranteed and the drug is costly.
Antivirals for Influenza Underutilized Among Vulnerable Children, Adolescents
Analysis of surveillance data revealed a decline in use of antiviral medications for children hospitalized with influenza and prevalent underprescribing in outpatient settings.
For Agitation in Alzheimer Disease, a Novel, Oral NMDA Receptor Antagonist Could be the Next Targeted Treatment
Geriatric psychiatrist and neurocognitive researcher George Grossberg, MD, highlights the mechanism of action for the new dextromethorphan/bupropion combination.
Treatment for Agitation in Alzheimer Dementia: Pipeline Preview with George Grossberg, MD
"It's a very rich pipeline because [agitation] is a very common and very debilitating symptom in Alzheimer's disease," Grossberg observed.
Exercise of Any Level Linked to Reduced All-Cause Mortality in Individuals with Dementia
Physical activity of any level before and after a diagnosis of dementia was associated with at least a 20% lower risk for all-cause mortality across dementia subtypes.
2025 GOLD Report for COPD: MeiLan Han, MD, MS, Discusses Addition of Dupilumab, Ensifentrine
The 2 newly approved COPD therapies have been added to the GOLD guidelines section on follow-up therapy, expanding clinical options for specific patient types.
Awareness of Lung Cancer Screening Extremely Low Among Those at Highest Risk in the US: New Data
Among current smokers, 71% had never spoken a clinician about screening and among those who had quit, 75% had never had a conversation.
Intensive SBP Reduction Below 120 mm Hg Reduces MACE in Adults with Type 2 Diabetes
AHA 2024. Findings from the BPROAD trial help fill a gap left by similar studies on the ideal target SBP for adults with type 2 diabetes, said study authors.
Agitation in Alzheimer Disease and Antipsychotics Used Off-Label are Not Meant for Each Other
Antipsychotic medications are still used to treat potentially harmful acute agitation, George Grossberg, MD, explains, even though the adverse effects are well known.
European Medicines Agency Reverses Opinion on Lecanemab for Alzheimer Disease But Limits Eligible Population
The EMA recommendation excludes from treatment adults who are homozygous for the ApoE ε4 gene, a decision that the US Alzheimer's Association does not support, said the president/CEO.
Risk Factors for Type 1 Diabetes: A Snapshot for Primary Care
About 40% of people who have T1D are not aware of it until they experience an extreme health event; screening in primary care can help reduce the risk, support families.