Study Identifies 6 Components of a Pregnancy Exercise Program that Reduce Risk of Poor Perinatal Outcomes
While exercise is beneficial during pregnancy and ACOG recommends 150 mins/week, this is the first study to examine benefits of specific regimen elements on their own.
Fezolinetant Demonstrates Reduced Waist Circumference, Body Roundness and Stable Weight and BMI in 52-Week Pooled Analysis of Phase 3 SKYLIGHT Trials
Postmenopausal women taking fezolinetant experienced positive changes in body fat distribution, increases in which are known to increase risks of cardiometabolic disease.
ACOG 2025: Poster Highlights for Primary Care
Details on 12 key abstracts with clinical relevance for primary care, from menopause management to PPD screening and HPV testing.
Elinzanetant Demonstrates Clinically Meaningful Reductions in Menopausal Vasomotor Symptoms, Meta-analysis Shows
Elinzanetant reduced VMS frequency and intensity, and improved sleep and quality of life, according to the meta-analysis to be presented at the ACOG 2025 meeting.
Normalizing Mental Health: A Vital Sign in Prenatal and Postpartum Care
The Role of Primary Care in Women's Health With Laurence Shields, MD
The two areas where primary care physicians can contribute to improving women's health, according to Laurence Shields, MD.
ACOG 2025 Refresh: Menopausal VMS Education in Primary Care
Building trust with patients early on will help them feel comfortable discussing their symptoms and treatment preferences, says JoAnn Pinkerton, MD.
ACOG opens 2025 Annual Clinical & Scientific Meeting, 'Powered by Purpose,' in Minneapolis
ACOG Issues Consensus Guidance to Improve Pain Control During In-Office Gynecologic Procedures
Every patient should be offered evidence-based analgesia for pain management for in-office uterine and cervical procedures after shared, trauma-informed decision-making.
TikTok Videos Found Inaccurate on Birth Control but Tweet Volume Appears Authoritative on Endometrial Cancer
More than half of TikTok videos reviewed on hormonal birth control were patient-created and misleading while the majority of posts on endometrial cancer were by clinicians.
Majority of Pregnant Patients Accepted RSV Protection in Vaccine's First Season
Two-thirds of pregnant individuals opted for either maternal vaccination against RSV or for neonatal monoclonal antibody therapy and for other vaccines recommended in pregnancy.
ACOG 2025: Menopause and Vasomotor Symptoms Preview
A preview of sessions covering menopause and vasomotor symptoms during ACOG 2025 in Minneapolis, MN.
Low Uptake of Hereditary Cancer Screening Among Breast Cancer Survivors Highlights Missed Opportunities for Preventive Care
In a cancer survivorship clinic in urban New York, only one-quarter of long-term breast cancer survivors received genetic testing, contrary to current recommendations.
For Recurrent Bacterial Vaginosis, Simplified Once-Weekly Treatment Found More Effective than CDC-Recommended Regimen
Secnidazole granules reduced recurrence rates to 20% over a period of 28 weeks in a small prospective pilot study, outperforming cumbersome daily regimens.
Evidence for Adverse Effects of High-Dose GC Treatment of Congenital Adrenal Hyperplasia Broadened, Deepened in New Literature Review
The most commonly reported adverse effects of high-dose glucocorticoid therapy were on bone health, cardiometabolic function, and height and growth.
Atopic Dermatitis Treatment Caution: Long-Term Oral Corticosteroid Use Ups Cardiovascular and Thrombotic Risks
The potential cardiovascular impact of prolonged oral corticosteroid therapy in the AD population observed in this study confirms longstanding cautions.
Semaglutide Linked to Reduced Risk for MACE Months Before Weight Loss Begins: Post Hoc Analysis
Semaglutide was associated with a significant reduction in risk for major adverse cardiovascular events after just 3 months of treatment in a population with established CVD.
Managing Vasomotor Symptoms of Menopause: A Topline Comparison of Treatments
Medical and nonpharmacologic treatment options for VMS range in efficacy and risk/benefit profile; a short slide show offers a topline look at how many compare.
Vasomotor Symptoms of Menopause: Facts At-a-Glance for Primary Care
Hot flashes and night sweats are just 2 of the myriad symptoms associated with menopause. Click through a quick refresher on the transition and effective treatments.
A Half Dose of Semaglutide Yields Weight Loss Equivalent to Clinical Trial Doses in Combination with Online Support Program
Semaglutide dosing was individually tailored for adults with obesity and supported with app-based coaching on diet, physical activity, and other lifestyle factors.
FDA Approves First At-Home Pap Smear Alternative for Cervical Cancer Screening, from Teal Health
The Teal Wand allows women to collect a vaginal sample in the privacy of their home and, according to Teal Health, the test has 96% accuracy for cervical precancer.
Tirzepatide Demonstrates Greater Weight Loss Than Semaglutide in Head-to-Head Study
Full results from the SURMOUNT-5 trial showed tirzepatide achieved 20.2% mean weight loss vs 13.7% with semaglutide in adults with obesity or overweight.
Novel TK1 Inhibitor Demonstrates Rapid, Dose-Dependent Efficacy in Atopic Dermatitis in Ph 1 Trial
Adults receiving the highest dose achieved 2 times the reduction in EASI scores vs placebo with responses emerging as early as day 8 of treatment.
Genetic Risk Score Identifies Individuals Likely to Report Adverse Events from GLP-1 Mimetic Therapy
The ability to predict which individuals will experience adverse events from GLP-1 therapy has great promise for more personalized treatment and improved clinical trial design.
LEO Pharma Announces Positive Preliminary Phase 2b Findings for Temtokibart in Atopic Dermatitis
The IL-22FA1 antagonist achieved positive outcomes for the primary endpoint based on percentage change in EASI from baseline to week 16 for 3 highest doses, according to LEO.
Crinecerfont Reduces GC Dosing, Improves Androstenedione Levels Across Multiple Pediatric Subgroups
Data for GC reduction and improved A4 levels were consistent across subgroups stratified by sex, race, age, BMI, and baseline A4 levels, according to Neurocrine Biosciences.
Cervical Cancer Screening Best Practices for Physicians
An interview with Jeff Andrews, MD, FRCSC, of BD Life Sciences.
Immunogenicity of Combined Flu/COVID-19 Vaccine Noninferior to Components in Older Adults
The investigational mRNA-1083 vaccine induced superior immune responses against all 4 flu strains in adults aged 50-64 years and against 3 in adults 65 and older.
Single Afternoon Dose of ICS Linked to Better Lung Function and Reduced Inflammation in Asthma
The chronotherapeutic approach aligns treatment with peak glucocorticoid sensitivity, so may mitigate onset of the inflammatory cascade that triggers nocturnal exacerbations.
Rising Lp(a) Levels Increase Risk of Subsequent CVD Events in Adults with ASCVD, According to Large Real-World Study
Any increase in lipoprotein(a) levels was linked to increased risk of myocardial infarction and stroke; women and Black adults are most likely to be affected.