Digital Asthma Self Management Program Improves Symptom Control But Disparities in Benefit Are Clear
A smartphone-based asthma management program significantly enhanced symptom control, but may require engagement or cultural tailoring to expand the effect.
Shingrix Prefilled Syringe Gets FDA Greenlight, According to GSK
The prefilled syringe presentation streamlines administration of the vaccine, eliminating the need to combine the lyophylized antigen and separate adjuvant.
Phase 3 Trials Begin for Once-Monthly Oral HIV Prevention Pill
Merck has launched phase 3 trials for MK-8527, a promising once-monthly HIV prevention pill, aiming to enhance PrEP options globally.
Digital Latency Measures Refine Early Detection of Cognitive Decline: Expert Review of Evidence
Digital latency measures enhance early detection of cognitive decline, revealing neurodegenerative changes before traditional tests indicate impairment.
Treatment of Neuropathic Pain: A Close Look at a New Meta-Analysis
For the often treatment-resistant pain of neuropathic conditions, the meta-analysis includes updated evidence for both pharmacologic and neuromodulatory interventions.
Otsuka and Lundbeck Will Face Scrutiny Over Investigational PTSD Therapy at July 18 FDA AdComm Meeting
FDA's Psychopharmacologic Drugs Advisory Committee will evaluate the novel brexpiprazole/sertraline combination, weighing efficacy against existing therapies amid mixed trial results.
Pre- and Post-Menopausal Hormone Therapy Has Differential Effect on Breast Cancer Subtypes
Combined estrogen-progestin hormone therapy used to manage VMS of menopause was associated with a higher risk of developing luminal-like breast cancer subtypes and other subtypes.
Monu Khanna, MD, on Why Cardiometabolic Screening Must Start Early in Patients with Obesity
Dr Khanna urges early screening for cardiometabolic risk in patients with obesity and highlights the role of primary care in prevention and education.
Lifestyle Medicine Is at a Tipping Point in the US, Expert Says, and It Could Be Just in Time
Without a shift in the approach to disease prevention and management in the US, the health system won't be able to handle the burden of our morbidity, says Richard Rosenfeld, MD, MPH, MBA.
Weight Loss Achievable Despite Interruptions in GLP-1 Medication Access, Study Finds
ENDO 2025. People with inconsistent access to GLP-1 medications still achieved clinically significant weight loss when therapy was combined with lifestyle changes and coaching.
New Guidelines Recommend Preconception Screening in Diabetes, Universal Testing for Primary Aldosteronism
ENDO 2025: The publications reflect growing consensus that integration of endocrine screening into standard clinical workflows is essential for early risk detection and long-term disease prevention.
Obesity Redefined: 1 in 5 Adults Reclassified Under New EASO Criteria
Individuals newly classified with obesity using the European framework were found to be overall sicker and at greater risk for mortality.
"Everyone is a Candidate for Some Positive Lifestyle Change," Guideline Author Suggests
Richard Rosenfeld, MD, MPH, MBA, led the development of lifestyle medicine guidelines to treat or even reverse prediabetes and type 2 diabetes.
Population-Wide Study Finds No Link Between Aluminum Exposure in Vaccines and Childhood Disorders
The Danish study analyzed a nationwide cohort of 2.1 million children and found no association between aluminum exposure and allergic, autoimmune, or neurodevelopmental conditions.
ENDO 2025: Most Patients With Classic Congenital Adrenal Hyperplasia Experience High Glucocorticoid Exposure or Suboptimal Control
A new analysis of the CAHtalog phase 3 study showed approximately 95% of participants experienced either high glucocorticoid exposure or elevated androstenedione levels during treatment.
The Role of Stress Reduction in Cardiometabolic Disease Management for Patients with Obesity
Monu Khanna, MD, discusses the benefits of behavioral strategies, including yoga, breathwork, and dancing, in reducing cardiovascular disease risk in patients with obesity.
Turn Therapeutics Launches First Clinical Trial to Assess Topical IL-36 Inhibitor for Atopic Dermatitis
GX-03 has proven effective in preclinical trials, reducing disease severity by more than 50% vs placebo. Data from the current study are expected by year end.
Maternal Depression Impairs Parental Emotional Responsiveness, Daily Care for Infants, Children: Global Systematic Review
Maternal depression significantly disrupts parenting behaviors, impacting child development and emotional bonding, according to an updated international literature review.
Lifestyle Medicine Guidelines for T2D, Prediabetes Are the Result of Remarkable Collaboration Across Specialties
Lead author for the American College of Lifestyle Medicine's new clinical practice guideline discusses the broad endorsement for the recommendations across participating groups.
Monu Khanna, MD: Essential Lifestyle Changes for Managing Obesity and Cardiometabolic Risk Factors
Obesity-Related Cancer Deaths More Than Tripled in the US from 1999 to 2020
ENDO 2025. Older adults, rural populations, and residents in the Midwest experienced the highest mortality rates, according to new data.
FDA to Review GSK's Application for Expanded Use of RSV Vaccine in High-Risk Adults Aged 18 to 49
GSK's RSV vaccine Arexvy would join shots from Pfizer and Moderna for the younger adult population, broadening choice for those with risk factors for severe disease.
FDA Approves Finerenone for Heart Failure With LVEF ≥40% Following Positive Phase 3 Data
FDA approval based on FINEARTS-HF trial showing 16% risk reduction in CV death and HF events.
AstraZeneca's Aldosterone Inhibitor Baxdrostat Effective Against Resistant HTN in Late-Stage Trial
Baxdrostat met the primary and all secondary endpoints, setting up a first regulatory filing for the selective aldosterone synthase inhibitor, according to AstraZeneca.
Treatment Options for Obesity-Related Cardiometabolic Diseases: Clinician Insights for Primary Care
Treatment should address root causes, including lifestyle modifications, stress management, and gut health, Monu Khanna, MD, told Patient Care.
Machine Learning Predicts Subjective Cognitive Decline During Menopause: Novel Framework for Early Detection
Key predictors of the severity of self-reported cognitive complaints among nurses going through menopause included symptom severity and climacteric stage.
Elinzanetant Gets UK Nod for Moderate to Severe Vasomotor Symptoms in Menopause: Is the US Far Behind?
Bayer's elinzanetant gains UK approval as the first dual-action, nonhormonal treatment for menopausal symptoms.
It Takes a Multispecialty Team to Support and Sustain Patient-Centered Lifestyle Behavior Change
Lifestyle medicine integrates a spectrum of therapeutic lifestyle interventions best delivered by specialists who are often available to create a "virtual" team.
9 Drugs Approved for Primary Care: Q2 2025
These new FDA-approved drugs include treatments for migraine, chronic spontaneous urticaria, RSV, and more.
Upstream Bio's TSLP Antagonist Verekitug Enters Global Phase 2 Trial for COPD
Verekitug is the only biologic in development for COPD that targets the TSLP receptor directly.