Single vs Multiple Inhaler Triple Therapy for COPD Could Triple Adherence, Persistence: International Data
CHEST 2024: Combined data from 4 continents found consistently better adherence/persistence when COPD triple therapy was initiated with a single inhaler.
Early Identification, Treatment of COPD Reduces Exacerbations, Health Care Burden
CHEST 2024. Initial treatment for people with COPD should begin early in the disease and leads to significantly reduced risk for exacerbations and inpatient treatment.
The Potential Harms of Breast Cancer Screening Need to be Explored and this Biostatistician is All In
The most common harm associated with breast cancer screening is a false positive finding; this UC Davis expert wanted to know more about how women respond.
Ensifentrine, Novel PDE3, PDE4 Inhibitor, Improves Lung Function, QoL Regardless of COPD Severity
The combined bronchodilator/anti-inflammatory agent significantly improved lung function, symptoms and QoL in adults with moderate or severe airflow obstruction.
New Data for Arexvy Show Vaccine Efficacy Through 3 RSV Seasons in Older Adults
Data on adults aged 60 years and older who received a single dose of the RSV vaccine indicate safety and reactogenicity consistent with the overall GSK phase 3 trial program.
FDA Black-Box Warnings on Antidepressants Linked to Reduced Treatment, Increased Risk of Suicide Among Youth
The FDA warnings were intended to increase physician monitoring for suicidal thoughts and behaviors but have had dramatic unintended consequences.
FDA Grants Marketing Authorization to First OTC Flu/COVID-19 Test Outside Emergency Use Declaration
The non-prescription test has more than 95% sensitivity and specificity for SARS-COV-2 and influenza A and B and delivers results in approximately 15 minutes.
Dronabinol May Have a Role for Quelling Agitation in Alzheimer Disease: New Data
The synthetic version of THC was associated with a 30% reduction in symptoms of agitation with none of the adverse effects seen with current treatments.
Albuterol/Budesonide Reduces Risk of Exacerbation in People with Intermittent, Mild-Persistent Asthma
Albuterol/budesonide (Airsupra) has now proven effective as novel combination as-needed rescue medication for adults with asthma regardless of disease severity.
FDA Approves Cologuard Plus, Next-Gen Noninvasive Colorectal Cancer Screening Test
Cologuard Plus bests its previous iteration and demonstrates greater sensitivity and specificity for any CRC relative to fecal immunochemical tests.
Migraine Survival Kit for Young People Headed to College
Help young patients with migraine (and their parents) get and stay prepared for the shift from home to college with this migraine survival kit checklist.
12 Facts About Colorectal Cancer for Primary Care Clinicians and Patients
Having a PCP is linked to higher rates of screening colonoscopy and improved overall survival. Review these 12 facts about CRC and share them with your patients.
8 Updates on Breast Cancer for Primary Care: Breast Cancer Awareness Month 2024
Breast cancer will claim the lives of more than 42 000 women in 2024. The primary care clinician's role as advocate for screening mammography can not be overemphasized.
Progression of Subclinical Atherosclerosis Independently Predicts All-Cause Mortality
The use of visual imaging to detect atherosclerosis at its earliest stages and to quantify the burden enhances predictive value of traditional risk assessment tools.
US Pertussis Cases Increase Nearly 5-Fold During 2024, According to the CDC
The surge in pertussis is likely a result of a return to pre-pandemic infection patterns coupled with waning immunity from previous vaccination, CDC says.
Suicide Attempts Reduced by 25% with Integrated Primary Care Intervention
A 14% increase in the rates of primary care safety planning within 2 weeks of a negative screening was associated 25% drop in the rate of attempted suicides.
RSV Mortality Higher than for Influenza B 90 Days After Hospital Discharge: New Data
Older adults hospitalized with RSV were older, more frail, and more likely to have respiratory comorbidities than those with influenza A or B, the study found.
What do Patients Want from Telehealth?
Telehealth offers convenience, saves time, and offers other benefits over office visits, but many people don't even know it's available to them, a new survey found.
FDA Approval of Dupilumab for Uncontrolled COPD will Change the Treatment Landscape: Interview with Surya Bhatt, MD, MSPH
Surya Bhatt, MD, MSPH, is coprincipal investigator for the 2 pivotal phase 3 clinical trials that supported today's landmark FDA approval of dupilumab for COPD.
Dupilumab Becomes First Biologic Approved in the US as Targeted Therapy for Adults with COPD
Dupilumab represents the first new treatment approach for uncontrolled COPD in more than a decade and reduced disease exacerbations by 34% in clinical trials.
New Oral Migraine Drugs Less Effective than Triptans for Acute Migraine Treatment
Triptan medications outperformed newer classes of oral migraine drugs, ie, gepants and ditans, on standard measures of efficacy for acute treatment.
Cancer Diagnosis Rates in 2021 Still Lagged Behind Projections Following Pandemic Effects
The decline in cancer diagnoses during the COVID-19 shutdown in 2020 did not lead to an expected compensatory increase in diagnoses in 2021, according to NCI researchers.
Lebrikizumab Demonstrates Sustained Disease Control in Atopic Dermatitis Up to 3 Years
Among adolescents and adults with moderate-to-severe AD, more than 80% achieved sustained disease control, the majority not requiring topical or systemic rescue medication.
Preconception Prediabetes Ups Risk for Poor Pregnancy Outcomes in Young Women: New Data
The risk of gestational diabetes was 2-fold greater among young women with prediabetes before conceiving compared with those who had normoglycemia.
FDA Accepts NDA for Delgocitinib Cream, Developed Specifically to Treat Chronic Hand Eczema
Delgocitinib specifically inhibits activation of JAK-STAT signaling in chronic hand eczema and would be an option for people unable to use topical corticosteroids.
COVID-19 Vaccines 2024-2025: Is America Ready and Willing?
COVID-19 vaccine myths of many types remain potent enough to raise public health experts' concerns about Americans' willingness to roll up sleeves this year.
Real-World Study Supports Use of DermaSensor in Primary Care to Differentiate Cancerous and Benign Lesions
The AI-based point-of-care device outperformed clinician standard of care for sensitivity (90% vs 40%) and had a negative predictive value of 98.9%
Erenumab Induces Remission in Chronic Migraine Medication Overuse Headache
Erenumab 140 mg safely and effectively induced remission in nonopioid MOH within 6 months in individuals for whom other preventive medications had failed.
First-Ever CGM Cleared for 365-Day Use
The only CGM system cleared for 1 year of use in type 1 and 2 diabetes is expected to be available in the fourth quarter of this year, the manufacturers said.
Co-administration of Arexvy and Shingrix Yields Positive Topline Phase 3 Data, GSK Reports
Immune responses for both vaccines were noninferior when given at the same visit compared with separate administration among adults aged 50 years and older.
