Obesity-Related Cancer Deaths More Than Tripled in the US from 1999 to 2020
ENDO 2025. Older adults, rural populations, and residents in the Midwest experienced the highest mortality rates, according to new data.
FDA to Review GSK's Application for Expanded Use of RSV Vaccine in High-Risk Adults Aged 18 to 49
GSK's RSV vaccine Arexvy would join shots from Pfizer and Moderna for the younger adult population, broadening choice for those with risk factors for severe disease.
FDA Approves Finerenone for Heart Failure With LVEF ≥40% Following Positive Phase 3 Data
FDA approval based on FINEARTS-HF trial showing 16% risk reduction in CV death and HF events.
AstraZeneca's Aldosterone Inhibitor Baxdrostat Effective Against Resistant HTN in Late-Stage Trial
Baxdrostat met the primary and all secondary endpoints, setting up a first regulatory filing for the selective aldosterone synthase inhibitor, according to AstraZeneca.
Treatment Options for Obesity-Related Cardiometabolic Diseases: Clinician Insights for Primary Care
Treatment should address root causes, including lifestyle modifications, stress management, and gut health, Monu Khanna, MD, told Patient Care.
Beyond Nutritional Deficiencies: Managing GLP-1 Side Effects With Lifestyle Interventions
Jonathan Bonnet, MD, MPH, discusses common side effects of GLP-1 medications for obesity and how nutritional and behavioral strategies can help mitigate them.
Machine Learning Predicts Subjective Cognitive Decline During Menopause: Novel Framework for Early Detection
Key predictors of the severity of self-reported cognitive complaints among nurses going through menopause included symptom severity and climacteric stage.
Elinzanetant Gets UK Nod for Moderate to Severe Vasomotor Symptoms in Menopause: Is the US Far Behind?
Bayer's elinzanetant gains UK approval as the first dual-action, nonhormonal treatment for menopausal symptoms.
It Takes a Multispecialty Team to Support and Sustain Patient-Centered Lifestyle Behavior Change
Lifestyle medicine integrates a spectrum of therapeutic lifestyle interventions best delivered by specialists who are often available to create a "virtual" team.
9 Drugs Approved for Primary Care: Q2 2025
These new FDA-approved drugs include treatments for migraine, chronic spontaneous urticaria, RSV, and more.
Upstream Bio's TSLP Antagonist Verekitug Enters Global Phase 2 Trial for COPD
Verekitug is the only biologic in development for COPD that targets the TSLP receptor directly.
Tralokinumab Update: Positive 16-Week Interim Results Reported for ADHAND Trial in Adults with Hand Eczema
Tralokinumab met key trial endpoints with no new safety signals in treatment of moderate-to-severe hand eczema, in adults who are candidates for systemic therapy.
Real-World Data Highlight Impact of Treatment Discontinuation on Obesity Pharmacotherapy Outcomes
A recent study highlights the importance of medication adherence for significant weight loss and improved glycemic control in obesity treatment with GLP-1 agonists.
Adult Vaccines in the US: More Shots, New Dynamics on the Horizon
The adult vaccine market is poised for explosive growth, with more than 100 product launches expected over the next 10 years. Are US clinicians ready?
FDA Grants Full Approval of Moderna’s COVID-19 Vaccine for High-Risk Children Aged 6 Months to 11 Years
Moderna’s Spikevax receives full FDA approval for use in children at increased risk for COVID-19, expanding protection ahead of the 2025–2026 virus season.
Investigational Rapid-Acting PTSD Medication Awarded FDA Breakthrough Therapy Status: Transcend Therapeutics Update
TSND-201, a rapid-acting neuroplastogen, demonstrated statistically significant symptom improvement by day 10, which was durable throughout the study until Day 64.
Lifestyle Medicine for Type 2 Diabetes: Is Mainstream Medicine Ready to be All In?
Richard Rosenfeld, MD, MPH, MBA, lead author of new guidelines on sustained lifestyle change as central to treating, even reversing T2D, answers the question.
Pain Management in Patients with Obesity: Clinician Insights on Balancing Pharmacological & Lifestyle Approaches
Monu Khanna, MD, discusses common medications, non-drug strategies, and holistic approaches to improve outcomes.
Donanemab Label Revised: New Dosing Schedule Approved for Early Alzheimer’s Treatment
The adjusted dosing for donanemab in early AD reduced ARIA-E risk by 41% compared to the original dosing, without compromising efficacy.
Quest Will Offer FDA-Cleared Fujirebio Blood Test to Detect Alzheimer Disease
The Fujirebio in-vitro diagnostic has shown positive and negative predictive values of 92% and 97%, respectively, for early AD detection and will be offered by end of summer.
GLP-1 Therapy for Obesity Requires Substantial Nutritional Framework, Multidisciplinary Support, Joint Advisory Warns
GLP-1 medications are transforming obesity medicine but strong evidence points to a need for integrating nutrition and lifestyle support for lasting weight loss and health benefits.
Diabetes Guidelines are Plentiful. The New One from the ACLM Can Support Them All
Richard Rosenfeld, MD, MPH, MBA, explains how clinical guidelines for diabetes remission from the American College of Lifestyle Medicine differ from and augment existing recommendations.
Monu Khanna, MD: Practical Pain Management Tips for Patients with Obesity
Dr Khanna discusses dosing challenges, metabolic issues, and potential complications from medications like acetaminophen.
The Weekly Dose: Clinical Updates on Cancer Detection, Cognitive Screening, CVD Prevention, Atopic Dermatitis Treatment
Discover essential clinical insights on Alzheimer disease screening in primary care, eczema treatments, and the latest in cancer detection and diet impacts on CHD risk.
New Data at IAS 2025 Underscore Real-World Success of Long-Acting Injectable HIV Therapies
New findings showcase the transformative impact of long-acting injectable therapies for effective HIV treatment and prevention.
5 Fall Prevention Tips for Your Older Adult Patients: Refresher for Primary Care
Exercise and strength/balance training are keys to protecting against falls, but careful assessments at each clinic visit may uncover other risks to address.
Body Fat Percentage Outperforms BMI in Predicting Mortality Risk in Young Adults: New Findings
Body fat percentage and waist circumference were both significantly associated with 15-year all-cause mortality while BMI had no significant association.
Clinic- and System-Level Factors Drive Racial Disparities in COVID-19 Antiviral Prescribing, Study Finds
A new study found racial disparities in COVID-19 antiviral prescribing, with clinic site, test type, and telehealth use explaining up to half the gap for Black and Latino patients.
Intranasal COVID-19 Vaccine Found Safe and Immunogenic in Open Label Phase 1 Clinical Trial
Among recipients of high-dose CVXGA, relative vaccine effectiveness was 67.8% against symptomatic COVID infection at a median 7.3 months post-vaccination.
Novel GLP-1/GLP-2 Agent Reduces Body Weight by Up to 8.3% in Phase 1b Obesity Trial
ADA 2025: Dapiglutide showed promising safety and weight loss results in a phase 1b trial, targeting obesity and inflammation with once-weekly dosing.
