January 16th 2025
The agency estimates that limiting nicotine levels could lead to 1.8 million fewer tobacco-related deaths by 2060 and health care savings of $1.1 trillion a year over the next 40 years.
January 13th 2025
The planned Phase 2 trial in IPF will focus on assessing MTX-463’s safety, pharmacokinetics, and efficacy.
January 8th 2025
The FDA approved the addition of Guillain-Barré syndrome warnings for Abrysvo and Arexvy, citing postmarketing data suggesting an increased risk.
December 18th 2024
The 2 novel vaccine candidates each combine a Sanofi licensed influenza vaccine with the Novavax adjuvanted recombinant COVID-19 vaccine.
Your daily dose of the clinical news you may have missed.
Juul Ban Prompts Praise from Physician Organizations
The FDA ban yesterday on Juul vaping devices and nicotine e-liquid pods drew praise from the American Medical Association, American Thoracic Society, American Lung Association, among others.
Patients with Moderate or Severe Asthma Benefit from High-intensity Interval Training, Study Finds
New findings suggest that HIIT may be an effective aerobic exercise option for asthma patients.
FDA Grants EUA for At-home Triple Test: COVID-19, Influenza, RSV
The Labcorp home test, available without a prescription, is delivered overnight and includes a return envelope. Results are available in 1-2 days.
Review of Biologic Treatments for Asthma Finds Inconsistent Effects on Airway Hyperresponsiveness
ATS 2022: Findings from a literature review provide insight into the mechanisms of airway hyperresponsiveness in asthma.
Majority of Asthma Patients Prescribed Dupilumab vs Other Biologics as Initial Rx, According to Extensive Real-world Analysis
ATS 2022: Dupilumab is often the first biologic agent prescribed for moderate-to-severe asthma according to analysis of a US database comprising more than 100 million patients.
Novel PDE4B Inhibitor Slows Lung Function Decline in IPF: Phase 2 Data from Boehringer Ingelheim
ATS 2022: The investigational PDE4B inhibitor slowed pulmonary decline in patients with IPF, both alone and with background use of approved antifibrotics.
Objective Confirmation of Asthma Diagnosis Often Missing in Primary Care, Study Suggests
ATS 2022: Charts from an EHR that included a suspected diagnosis of asthma either had no objective documentation or mentioned a test but included no results.
Adults with Asthma Found at Higher Risk for Obesity in International Study
The observational study found that longer duration of disease conferred a 32% greater risk of obesity and that nonatopic asthma carried at 47% greater risk.
Pulmonary Rehab Improves Lung Function, QOL in Asthma-COPD Overlap Plus Obesity
Asthma-COPD overlap and obesity mutually exacerbate each other and an early program of pulmonary rehabilitation shows promise to help both.
Novel Agent for Severe Asthma Halves Exacerbation Rates Across Respiratory Comorbidities
Tezepelumab, a TSLP inhibitor, reduced asthma exacerbation rates in patients with severe uncontrolled disease across a range of respiratory comorbidities.
American Academy of Asthma, Allergy & Immunology 2022 News Highlights
AAAAI late-breaking science and findings that could change your treatment plan for patients with severe asthma, summarized by our editors for easy access.
Asthma May be Linked to Severe COVID-19 but Not to Risk for Hospitalization
Patients with asthma who did require hospitalization for SARS-CoV-2 infection were at greater risk for intubation and remdesivir treatment, a new study reports.
Severe Asthma Research Quiz: 8 Questions on Notable New Findings
New study findings on asthma exacerbation risk prediction, rapid steroid reduction, and patient perception of disease lead this quick quiz.
Racial/Ethnic Bias Found in Asthma Clinical Trials Used to Update NHLBI Guideline
In the majority of studies that reported racial/ethnic data, White participants were highly overrepresented and Black/Hispanic/all Other underrepresented.
Severe Asthma Research Recap: 8 Updates for Primary Care
Research summaries on GINA revisions, a steroid-reduction algorithm, factors that predict asthma exacerbation risk, and more.
New Study Identifies Key Risk Factors Likely to Accelerate a COPD Diagnosis in Patients with Asthma
New research highlights several key risk factors that are likely to accelerate the progression from asthma to COPD, including older age and prior tobacco use.
Severe Uncontrolled Asthma: 5 Questions on Key Characteristics
Optimal use of biologic therapy for severe uncontrolled asthma rests on understanding of the disease itself. Try this quick quiz to test your knowledge.
Tezepelumab Reduces Exacerbations in Patients with Severe Asthma Regardless of Season
New data from the phase 3 NAVIGATOR trial demonstrate superior efficacy of tezepelumab to reduce asthma exacerbations in severe disease year round.
Workplace Pesticide Exposure Tied to Higher Risk of COPD, Suggests New Study
Occupational exposure to pesticides was linked to an increased risk of COPD in a large UK study.
Omicron Subvariant BA.2: What We Know Now
Known as BA.2, the new Omicron subvariant is now circulating at low levels in the US. What can you tell your patients? Here's what we know, now.
7 COVID-19 Home Test Kits Ranked by Usability
Seven at-home COVID-19 rapid tests, all available online or at retail, are ranked for dexterity required, instruction legibility, and other features you may need to parse for your patients.
Pop Flu Quiz: What does the CDC say?
The CDC recommends ASAP use of antivirals in certain high-risk patient groups. Test your memory of who is in those groups with 2 short questions.
Pfizer COVID-19 Oral Antiviral Still Nearly 90% Effective Against Severe Disease
Pfizer reported today final results of the phase 2/3 EPIC-HR trial, findings that confirm the investigational drug's 89% efficacy against severe COVID-19 disease.
Guideline Toplines: 2021 Clinical Focus Collection
The Guideline Toplines slide-show feature offers busy primary care physicians at-a-glance summaries of new and updated clinical guidelines across therapeutic areas.
Influenza Virus: How well do you know this enemy?
The flu is well known to all primary care providers - but contributor Terry Brenneman, MD, created 6 questions on topics you might not ordinarily discuss. Quiz time.
Flu Season 2021-2022: Primary Care Fears & Patients on the Fence
This flu season will bring different challenges to primary care clinicians. Here, experts discuss specific barriers and best strategies to overcome them.
PCP Visits Associated with Smoking Cessation after Lung Cancer Diagnosis and Before Surgery
CHEST 2021: Among >7000 veterans diagnosed with lung cancer and scheduled for surgery, seeing a primary care doctor was linked to pre-operative quitting.
Study: Hispanic Adults, Women, and Older E-cigarette Users Face Higher Odds of Asthma and COPD
CHEST 2021: Study shows vaping raises the odds of developing asthma and COPD, especially in older adults, women, and Hispanic persons.
Biologics Reduce Severe Asthma Exacerbations in Real-world Study of Vulnerable Patients
CHEST2021: The CHRONICLE study of biologics to treat severe asthma found reductions in exacerbations of more than 50% in patient groups not included in clinical trials.
Tezepelumab May Improve Peak Expiratory Flow in Patients with Severe Asthma, Suggests Analysis of NAVIGATOR Trial
CHEST 2021: Patients with severe asthma who received tezepelumab compared with placebo demonstrated rapid improvement in morning and evening peak expiratory flow.