January 16th 2025
The agency estimates that limiting nicotine levels could lead to 1.8 million fewer tobacco-related deaths by 2060 and health care savings of $1.1 trillion a year over the next 40 years.
January 13th 2025
The planned Phase 2 trial in IPF will focus on assessing MTX-463’s safety, pharmacokinetics, and efficacy.
January 8th 2025
The FDA approved the addition of Guillain-Barré syndrome warnings for Abrysvo and Arexvy, citing postmarketing data suggesting an increased risk.
December 18th 2024
The 2 novel vaccine candidates each combine a Sanofi licensed influenza vaccine with the Novavax adjuvanted recombinant COVID-19 vaccine.
Your daily dose of the clinical news you may have missed.
Remdesivir New Drug Application Submitted to FDA
The investigational antiviral remdesivir in phase 3 clinical trials led to faster time to recovery vs placebo and was found to be safe.
Fever and Headache, then Cough, in a 52-year-old Woman
Patient's vital signs and results of physical examination are normal; results of a previous lumbar puncture also were normal. What does the chest x-ray reveal?
FDA Approves Triple Fixed-dose Inhaled Therapy for COPD
Approval was awarded to AstraZeneca for an inhaled, fixed-dose combination of budesonide/glycopyrrolate/formoterol fumarate.
Study: After COVID-19, Symptoms Persist for Majority of Patients
JAMA: After recovery from COVID-19, a majority of patients reported persistence of at least 1 symptom; more than half reported ≥3 symptoms.
Reducing Risk of Severe Dyspnea-related Psychological Trauma in COVID-19 Survivors
Prolonged "air hunger" induced during mechanical ventilation for severe COVID-19 infection can be eliminated by a change in standard of care, a new paper suggests.
Asthma, COPD Inhaler Adherence Up During Pandemic
Adherence to controller medication appears to have increased between early January and late March among patients with asthma and COPD, finds a new study.
Vaping-related Hospitalization, Mortality: A Quiz on New CDC Guidance
Try your hand at these 8 questions based on the latest CDC guidance on rehospitalization and mortality in patients with vaping-related lung injury.
3 Strategies to Optimize Facemask Supply: Conventional, Contingency & Crisis Plans
The CDC outlines 3 surge capacity strategies to help healthcare providers prioritize COVID-19-related conservation of facemasks: conventional, contingency, and crisis.
4 Lung Disease Study Briefs for Primary Care
Testosterone could protect women from asthma and niacin may decrease COPD severity in men--results of 2 of these 4 studies. Read more.
Stroke Risk Nearly Triples with Dual Vaping, Combustible Cigarette Use
A new study found a significant association between increased stroke risk and dual use of e-cigarettes and traditional cigarettes-authors urging physicians to use results as a wake-up call.
Managing EVALI Patients during Flu Season: 6 CDC Recommendations
These 6 recommendations from the CDC can aid physicians in differential diagnosis and treatment of EVALI and the flu.
Vaping-Related Lung Injury: New CDC Recommendations for Primary Care Physicians
The multistate outbreak of vaping-related lung injury is ongoing, but the CDC's updated interim guidance can help physicians navigate the clinical evaluation and management of these patients.
Vaping-Related Lung Injury in the US: A Pop Quiz
How current are you on the outbreak of lung injuries associated with e-cigarette use, as of today? Take our pop quiz on the latest facts and figures to find out.
Lung Injury Associated with E-Cigarette Use: An Update
Get highlights from a new CDC report with the most recent number of reported cases, patterns of the outbreak, patient characteristics, and more.
ED Use in COPD Linked to Depression, Loneliness
Findings: COPD patients who are lonely and depressed are at increased risk for ED use and hospital admission. Even mild depression is a risk factor.
COPD Insights for Primary Care: 5 New Studies
Findings: Don’t blame patients for all inhaler-use errors; singing may help improve breathing, QOL; Rx adherence does improve over time; plus 3 more outcomes of interest.
Components and Health Consequences of Electronic Cigarettes
A pulmonologist summarizes key research and guidance on the harmful effects of e-cigarettes.
Cystic Fibrosis Guideline Update: 7 Questions
Cystic fibrosis treatment guidelines must evolve to keep pace with new treatments and disease knowledge. Try 7 questions on the latest iteration.
New CF Adherence Intervention Starts Strong
Pilot study success with a new cystic fibrosis treatment adherence tool may augur similar positive results from current RCT. Outcomes are due, soon.
Vaping-related Respiratory Disease Requires Intubation for Some
Recent vaping behavior is the only commonality found among teens and young adults hospitalized in 2 midwestern states, for severe respiratory symptoms.
ATS Highlights Advances in the Prediction of COPD Outcomes
DALLAS--Results of 3 studies presented at the American Thoracic Society meeting this week focus on the predictive role of disease exacerbations, machine learning, and Hgb levels in COPD.
E-Cigarettes: The New Addiction and Why Physicians Must be Concerned
DALLAS-At the American Thoracic Society meeting thought leaders cited disturbing trends in e-cigarette use by teens and warned of health dangers, known and unknown.
Choking and Chest Tightness: Asthma or Something Else?
A 37-year-old man recently was diagnosed with asthma and prescribed a dry-powder inhaler. He says it's not working and actually making his symptoms worse. What's wrong?
3 Things Your COPD Patients May Not Tell You
"I'm having trouble catching my breath." "I can't pay for my inhaler." "I'm just so sad." They may not tell us, so we need to ask. Here's my experience.
Why Physicians Fire Patients: My Informal Survey
Only 1 respondent to this physician’s poll had never discharged a patient. Those who had cited abusive behavior, dangerous noncompliance, intuition, and more.
Older Man with Cough and Shortness of Breath: A Surprising Diagnosis
Simultaneous events can confuse a clinical picture. In this case, the ECG offers clues to an event that occurred during an episode of bronchitis.
Progressive Dyspnea & Chronic Cough: One Disease or Two?
Beth is age 52, smokes 2 packs of cigarettes a day, gets breathless in cold weather, and has had "bronchitis" twice this year. What's your diagnosis?
Mild Asthma, Poorly Controlled: A Case In Point
"Cindy" says she's using her albuterol inhaler up to 6 times a day, but her asthma is worse. A pulmonologist poses 4 questions that can lead to preferred Rx.
Idiopathic Pulmonary Fibrosis: How to Recognize and When to Refer
This compact yet detailed slide show offers primary care physicians a guide to essentials of IPF diagnosis and when to refer for pulmonary consult.
A Non-smoker with Progressive Dyspnea, No Cough
Dorothy is 55-years-old, has never smoked, and was well until 1 year ago when she first noticed mild dyspnea on exertion; it has gotten progressively worse.