January 16th 2025
The agency estimates that limiting nicotine levels could lead to 1.8 million fewer tobacco-related deaths by 2060 and health care savings of $1.1 trillion a year over the next 40 years.
January 13th 2025
The planned Phase 2 trial in IPF will focus on assessing MTX-463’s safety, pharmacokinetics, and efficacy.
January 8th 2025
The FDA approved the addition of Guillain-Barré syndrome warnings for Abrysvo and Arexvy, citing postmarketing data suggesting an increased risk.
December 18th 2024
The 2 novel vaccine candidates each combine a Sanofi licensed influenza vaccine with the Novavax adjuvanted recombinant COVID-19 vaccine.
Your daily dose of the clinical news you may have missed.
Daily Dose: Waist-to-Hip Ratio Better Predictor for Mortality than BMI?
Daily Dose: Long-COVID Rehabilitation Interventions
Daily Dose: Dupilumab Potent Against Uncontrolled COPD with Type 2 Inflammation
Waist-to-Hip Ratio More Consistently Associated with Mortality vs BMI: New Research
Waist-to-hip ratio was more powerfully and consistently associated with risk of all-cause mortality than BMI or FMI, but can it replace BMI as a clinical indicator?
Long-COVID Rehabilitation Interventions Improve Symptoms but Research on Safety Still Needed
Meta-analysis: Among persons with symptoms of long COVID, respiratory and exercise training were effective but pooled information on safety was "uncertain, imprecise."
Dupilumab Potent Against Uncontrolled COPD with T2 Inflammation: BOREAS Trial Update
Reduced exacerbations, improved lung function, increased QoL, and less use of systemic corticosteroids underscore dupilumab's effects against type 2 inflammation.
FDA Approves Updated COVID-19 Monovalent Vaccines for 2023-2024
As COVID-19 hospitalizations increase at the opening of the respiratory virus season, the first "seasonal" vaccine against the virus is ready for roll-out, says the FDA.
Keep the Vaccination Conversation Going—and Cheerlead, Too
"Keep the vaccination conversation going this year, even though your patients, and probably you, too, have grown tired of the issues and your team is worn out."
Daily Dose: Characteristics of RSV-Related Critical Illness in Infants during 2022 Peak
A daily dose of clinical news on Patient Care you may have missed.
FDA Approves First RSV Vaccine for Use in Pregnant Individuals to Prevent LRTD in Infants
The FDA approved Abrysvo for use in pregnant individuals to prevent LRTD and severe LRTD caused by RSV in infants from birth through 6 months of age.
US Infants Admitted to ICU in 2022 for RSV Mostly Young, Healthy, and Born at Term
Approximately 80% of infants hospitalized with an RSV-related illness during the 2022 seasonal peak did not have underlying medical conditions, according to new study.
Long-term Smokers Have Symptomatic Lung Disease that is Not COPD, Has No Treatment
Despite a 20-pack year smoking history and frequent respiratory exacerbations, spirometry is preserved in this group of heavy smokers.
Seen in the ED: Pleuritic Back Pain in a Middle-Aged Woman
The patient presents with pleuritic pain but without fever, SOB, chest pain or cough. Review the CXR - what's your diagnosis?
5 Questions on CDC Updates to COVID-19 and Flu Vaccine Guidance
Updates to CDC recommendations on influenza and COVID-19 vaccines and vaccine formulations will impact your choices during flu season this year.
Nirsevimab-alip Gets Unanimous ACIP Recommendation to Prevent RSV in Neonates, Infants
The ACIP was unanimous in its recommendation for routine use of nirsevimab-alip to prevent RSV LRTD in newborns and young infants during their first RSV season.
Merck's 21-Valent Adult Pneumococcal Vaccine Meets Key Endpoints in Pair of Phase 3 Trials
Statistically significant positive immune responses were observed in both vaccine-naive adults and those previously vaccinated, including for the vaccine's 8 unique serotypes.
When We Talk about RSV Vaccines, We Need to Remember COVID-19, Says Public Health Leader
The arrival of COVID-19 vaccines challenged many people for the first time to understand the actual public health role of vaccination. With the RSV shots, it may be round 2.
FDA Grants 501(k) Clearance to Triple Assay for Influenza, RSV, and COVID-19
The triple assay can identify and differentiate influenza, COVID-19, and respiratory syncytial virus in approximately 2 hours and is already in use.
Influenza Vaccination 2023-2024: ACIP Recommendations and Changes
ACIP guidance on influenza vaccination for the 2023-2024 respiratory virus season includes updates important for primary care clinicians.
Daily Dose: Preoperative HIIT and Cardiorespiratory Health Among Adults Undergoing Major Surgery
Your daily dose of clinical news you may have missed.
New Research Suggests Preoperative High-intensity Interval Training is Beneficial for Cardiorespiratory Health
Findings from meta-analysis showed preoperative high-intensity interval training was associated with improvements in exercise capacity and a reduction in postoperative complications.
Flu Vaccination for Children May Reduce Hospitalization for RSV, Suggest New Data
The influenza vaccine may offer a protective effect against hospitalization for respiratory syncytial virus in young children, suggest data from Australia.
When COVID-19 Vaccines & Treatment Aren't Free, What Will they Cost?
In the post COVID-19 pandemic health care emergency era, private and public insurance entities will continue full coverage of the shots - but what about the uninsured?
E-Cigarettes: US Sales Nearly Double over 2 Years, Youth Prefer Flavored Disposables
Sales of e-cigarettes in the US jumped by 46% from 2020-2022; rapid market shifts beg coordinated restrictions to protect public health, says the CDC.
FDA Advisory Committee Unanimous: COVID-19 Vaccines Should be Monovalent, Contain XBB Strain
The FDA's VRBPAC members were unanimous in their recommendation that the 2023-24 COVID vaccines reflect the dominant strain in circulation, XBB.
Daily Dose: RSV LRTI in Infancy Linked to More Clinical, Pulmonary Function Sequelae
The Race for an Adult RSV Vaccine: The Last Leg
The FDA has approved 2 vaccines against respiratory syncytial virus in older adults—with final details pending. This 2-question quiz tests how closely you've been following.
We Need the Updated Bivalent COVID-19 Booster, Don’t We?
Need more talking points to help patients grasp the importance of the bivalent COVID-19 vaccine? The answers to these 3 questions should help.
Nirsevimab Gets FDA Advisory Committee Recommendation to Prevent RSV in Infants
Nirsevimab, a long-acting monoclonal antibody, if approved, will be indicated to prevent RSV LRTD in neonates and infants born during or entering into their first RSV season.
STUDY: Infants Hospitalized for RSV with LRTI Face Increased Symptoms and Lung Function Abnormalities by Age 2
Children hospitalized for RSV with LRTI during infancy have increased symptoms and lung function abnormalities, including increased resistance and decreased compliance.