Editor of Patient Care Online.
Tralokinumab Update: Positive 16-Week Interim Results Reported for ADHAND Trial in Adults with Hand Eczema
Tralokinumab met key trial endpoints with no new safety signals in treatment of moderate-to-severe hand eczema, in adults who are candidates for systemic therapy.
Obesity and Chronic Pain: Monu Khanna, MD, on Breaking the Vicious Cycle
Dr Khanna breaks down the bidirectional relationship and explains why standard pain management often falls short for people with obesity.
Real-World Data Highlight Impact of Treatment Discontinuation on Obesity Pharmacotherapy Outcomes
A recent study highlights the importance of medication adherence for significant weight loss and improved glycemic control in obesity treatment with GLP-1 agonists.
Adult Vaccines in the US: More Shots, New Dynamics on the Horizon
The adult vaccine market is poised for explosive growth, with more than 100 product launches expected over the next 10 years. Are US clinicians ready?
FDA Grants Full Approval of Moderna’s COVID-19 Vaccine for High-Risk Children Aged 6 Months to 11 Years
Moderna’s Spikevax receives full FDA approval for use in children at increased risk for COVID-19, expanding protection ahead of the 2025–2026 virus season.
Investigational Rapid-Acting PTSD Medication Awarded FDA Breakthrough Therapy Status: Transcend Therapeutics Update
TSND-201, a rapid-acting neuroplastogen, demonstrated statistically significant symptom improvement by day 10, which was durable throughout the study until Day 64.
Pain Management in Patients with Obesity: Clinician Insights on Balancing Pharmacological & Lifestyle Approaches
Monu Khanna, MD, discusses common medications, non-drug strategies, and holistic approaches to improve outcomes.
Donanemab Label Revised: New Dosing Schedule Approved for Early Alzheimer’s Treatment
The adjusted dosing for donanemab in early AD reduced ARIA-E risk by 41% compared to the original dosing, without compromising efficacy.
Quest Will Offer FDA-Cleared Fujirebio Blood Test to Detect Alzheimer Disease
The Fujirebio in-vitro diagnostic has shown positive and negative predictive values of 92% and 97%, respectively, for early AD detection and will be offered by end of summer.
GLP-1 Therapy for Obesity Requires Substantial Nutritional Framework, Multidisciplinary Support, Joint Advisory Warns
GLP-1 medications are transforming obesity medicine but strong evidence points to a need for integrating nutrition and lifestyle support for lasting weight loss and health benefits.
Unnecessary Cancer Screenings in the US Persist Long After Guidelines Shift: Daily Dose
Your daily dose of the clinical news you may have missed.
Monu Khanna, MD: Practical Pain Management Tips for Patients with Obesity
Dr Khanna discusses dosing challenges, metabolic issues, and potential complications from medications like acetaminophen.
The Weekly Dose: Clinical Updates on Cancer Detection, Cognitive Screening, CVD Prevention, Atopic Dermatitis Treatment
Discover essential clinical insights on Alzheimer disease screening in primary care, eczema treatments, and the latest in cancer detection and diet impacts on CHD risk.
New Data at IAS 2025 Underscore Real-World Success of Long-Acting Injectable HIV Therapies
New findings showcase the transformative impact of long-acting injectable therapies for effective HIV treatment and prevention.
5 Fall Prevention Tips for Your Older Adult Patients: Refresher for Primary Care
Exercise and strength/balance training are keys to protecting against falls, but careful assessments at each clinic visit may uncover other risks to address.
Body Fat Percentage Outperforms BMI in Predicting Mortality Risk in Young Adults: New Findings
Body fat percentage and waist circumference were both significantly associated with 15-year all-cause mortality while BMI had no significant association.
Obesity and Type 2 Diabetes: Expert Shares 4 Pillars of Management
Caissa Troutman, MD, discusses how clinicians can tailor management plans to reduce risk of developing T2D in patients with obesity.
Clinic- and System-Level Factors Drive Racial Disparities in COVID-19 Antiviral Prescribing, Study Finds
A new study found racial disparities in COVID-19 antiviral prescribing, with clinic site, test type, and telehealth use explaining up to half the gap for Black and Latino patients.
Intranasal COVID-19 Vaccine Found Safe and Immunogenic in Open Label Phase 1 Clinical Trial
Among recipients of high-dose CVXGA, relative vaccine effectiveness was 67.8% against symptomatic COVID infection at a median 7.3 months post-vaccination.
Novel GLP-1/GLP-2 Agent Reduces Body Weight by Up to 8.3% in Phase 1b Obesity Trial
ADA 2025: Dapiglutide showed promising safety and weight loss results in a phase 1b trial, targeting obesity and inflammation with once-weekly dosing.
Apogee Hopes Raised by Phase 2 Data for APG777 to be a Best-In-Class for Atopic Dermatitis
The investigational IL-13 inhibitor showed topline EASI-75 of 66.9% and reduced injection frequency in part A of the APEX phase 2 clinical trial.
Fad Diets and TikTok Nutrition Influencers: 90% of Clinicians Are Concerned, Survey Says
Social media support for the Keto diet and raves about the next best dietary supplement worry HCPs; they also feel their own nutrition education is subpar.
Real-World Weight Loss With GLP-1s Falls Short of Trial Results: Daily Dose
Long-Term Data Support Roflumilast Cream for Pediatric Atopic Dermatitis: Daily Dose
Mental Health Burden in Atopic Dermatitis: Study Identifies Key Risk Factors for Anxiety and Depression
Depression and anxiety affect as many as 1 in 4 people with AD, with pruritus, sleep disorders, education level, and comorbidities identified as independent risk factors.
Circulating Inflammatory Cells Persist in Severe Asthma Despite Biologic Therapy, Study Shows
Research from the Karolinska Institute reveals that therapies such as dupilumab and mepolizumab may not eliminate Th2 lymphocytes, raising concerns about long-term remission.
FDA Backs Shield Test for Broad Early Cancer Screening: Daily Dose
Phase 2b Study of Psychedelic BPL-003 Shows Rapid, Persistent, and Significant Improvement in Treatment Resistant Depression
A single dose of BPL-003 was associated with improved MADRS scores as early as day 2 that were durable through week 8; phase 3 planning is anticipated.
Majority of Americans (8 in 10) Support Routine Childhood Vaccine Requirements, According to New Harvard Poll
As authorities record data on the largest US measles outbreak in decades, 79% of Americans support school vaccine mandates for children, an encouraging result.
Mayo Clinic AI Tool Allows Rapid, Precise Identification of 9 Types of Dementia From Single Brain Scan
The StateViewer clinical decision support system could help expand access to specialist-level insights in clinics that lack neurology expertise, according to researchers.
