Editor of Patient Care Online.
Vaccine Hesitancy: Communication Strategies for Primary Care That Preserve Trust
Amesh Adalja, MD, infectious disease physician, outlines effective communication strategies that respect patient concerns while reinforcing physician credibility.
FDA Label Update Positions Inclisiran as First-Line Monotherapy for Hypercholesterolemia
Inclisiran can now be used without a background statin, as an adjunct to changes in diet and physical activity for reduction of LDL-C in hypercholesterolemia.
Lecanemab Shows Sustained Benefit at 4 Years in Early Alzheimer Disease: AAIC 2025
Four-year data show lecanemab slows clinical decline in early Alzheimer disease and maintains a consistent safety profile.
Tirzepatide Proves Noninferiority With Dulaglutide for MACE in Lilly's Landmark Incretin Face-Off
In the SURPASS-CVOT trial, tirzepatide reduced MACE-3 by 8% and all-cause mortality by 16% compared with dulaglutide, while also reducing HbA1c and weight.
New Option for Chronic Hand Eczema Gets FDA Green Light: Daily Dose
Your daily dose of the clinical news you may have missed.
New Data Highlight Significant Challenges to Managing CAH: Daily Dose
Amesh Adalja, MD, on How to Defuse Vaccine Safety Concerns Without Derailing the Visit
Dr Adalja offers evidence-based strategies to address patient concerns about aluminum and thimerosal in vaccines.
FDA Grants Fast Track Designation to Rezpegaldesleukin for Alopecia Areata
FDA grants Fast Track designation to rezpegaldesleukin for severe alopecia areata, highlighting its potential to meet critical treatment needs.
Maternal Depression Found to Disrupt Emotional Responsiveness, Infant Care: Daily Dose
Amesh Adalja, MD, Breaks Down 2025 Vaccine Policy Shifts for Primary Care
Infectious disease expert Amesh Adalja, MD, outlines the biggest vaccine policy shifts of 2025, including changes to COVID-19 and flu vaccine recommendations.
Donanemab Showed Sustained Cognitive Benefit Over 3 Years in Early Alzheimer Disease
Three-year follow-up data from the TRAILBLAZER-ALZ 2 extension trial supported early initiation and limited-duration dosing.
Alzheimer's Association Releases First Clinical Guideline on Use of Blood-Based Biomarker Tests
The guideline is the first in a series that will focus on diagnosis, treatment, and care of Alzheimer disease and all other dementias, according to the association.
No Link Found Between Aluminum in Routine Vaccines and Childhood Disorders: Daily Dose
Why 4 Medical Societies Issued a Joint Advisory on Nutrition and GLP-1 Therapy for Obesity
Coauthor of a recent joint advisory, Jonathan Bonnet, MD, MPH, explains how it emerged in response to the growing use of GLP-1 medications for obesity treatment.
Remote Cognitive Screening Platform Expands Access to Early Detection
Linus Health is expanding its AI-powered remote cognitive assessment platform, Anywhere, to expand access to early detection of cognitive impairment.
Solriamfetol Treatment Yields Cognitive Gains in Obstructive Sleep Apnea: Daily Dose
Trontinemab Phase 3 Alzheimer Trials to Launch Following Promising Amyloid Clearance Data
Data from Roche presented at AAIC 2025 highlight rapid amyloid clearance with investigational antibody and potential of pTau217 as blood-based rule-in and rule-out test.
Impact of Social Stigma on Mental Health among Women with Obesity: An Expert’s View
Shagun Bindlish, MD, board member of the ADA, discusses how societal weight-related stigma contributes to mental health challenges faced by women with obesity.
Low-Value Cancer Screenings Persist Despite Guidelines: Daily Dose
The Obesity–Cardiometabolic Link: Root Causes, Screening, and Primary Care's Role
Obesity medicine specialist Monu Khanna, MD, discusses the critical role of primary care in obesity-related risk reduction through lifestyle, behavior, and emerging therapies.
In Screening for Dementia, Time Can Tell A Lot: A Conversation with Researcher David Libon, PhD
In this short conversation, Libon underscores how time-based measures during assessment can reflect subtle neurocognitive changes, augmenting traditional screening.
Intranasal Epinephrine Should Be Prescribed with Confidence, Editorial Encourages
Clinical skepticism about the parity in effectiveness of epinephrine delivered via nasal spray vs autoinjector is rooted in fixed assumptions that bear examination, authors say.
FDA Extends Review Period for Elinzanetant NDA for Menopausal Vasomotor Symptoms
Bayer's elinzanetant, a potential nonhormonal treatment for menopausal symptoms, awaits FDA approval after a 90-day review extension.
Nirsevimab Highly Effective in Preventing RSV-Related LRTD in Healthy Term Infants, Real-World Study Finds
Nirsevimab lowered the risk of RSV-related illness by over 87% and hospitalizations by 98% in a new study.
7 Common Causes of Dementia: A Topline Review
The brain changes that lead to cognitive and behavioral changes referred to as dementia have multiple potential etiologies; not all dementia is Alzheimer disease.
Late-Life Mood Disorders May Represent Prodromal States of Dementia: Daily Dose
AI-Generated Dermatologic Images Show Poor Diagnostic Accuracy, Underrepresent Skin of Color
In response to the prompt, "Generate a photo of a person with [skin condition]," 3 of 4 generative AI models significantly underrepresented diverse skin tones.
Make It Routine: Screening for Cognitive Decline in Primary Care
Listen to our latest podcast episode to discover how early dementia detection enhances care and quality of life, with actionable strategies for primary care teams to implement now.
Influenza Vaccination Reduces Disease Burden in Both Vaccinated and Unvaccinated, Modeling Study Finds
Vaccination lowered influenza cases by about 33% to 42% in seasonal flu setups with 40% vaccine effectiveness, researchers reported.
FDA Grants Fast Track Designation for Sprout's Flibanserin to Treat HSDD in Postmenopausal Women
Low sexual desire affects up to 40% of women across the lifespan but currently there is no treatment option for those beyond their reproductive years.
