Editor of Patient Care Online.
Sanofi, Regeneron's IL-33 mAb Misses Primary Endpoint in Late-Stage COPD Trial
Itepekimab performed well in the phase 3 AERIFY-1 trial but fell short of anticipated outcomes in AERIFY-2, prompting further analysis after the mixed results.
AI Tool Enhances Breast Cancer Detection, Spotting Missed Tumors: Daily Dose
Your daily dose of the clinical news you may have missed.
High-Quality Carbohydrates in Midlife Linked to Healthier Aging in Women
For every 10% increase in energy from high-quality carbohydrates, the odds of healthy aging rose by 31%, according to an analysis of data from the Nurse's Health Study.
Enobosarm Significantly Preserves Muscle Mass When Added to Semaglutide, Advances to Phase 3 Development Program
Enobosarm added to semaglutide shows promising results in preserving muscle mass while promoting fat loss in older adults, according to developer Veru, Inc.
Real-World Study Confirms Upadacitinib’s Efficacy in Crohn Disease Treatment: Daily Dose
Provider Gaps in Postpartum Depression Screening and Management Highlighted in New Study
ACOG 2025: Laxmi Gannu, MS, discusses key findings from a provider survey on postpartum depression screening practices, training gaps, and referral patterns.
Dosing Begins in Phase 2b Trial of Investigational Oral COVID-19 Vaccine Candidate
Vaxart's phase 2b trial for its oral COVID-19 vaccine follows a positive safety review and aims to enroll 10,000 participants in the US.
ASCO 2025: GLP-1 Receptor Agonists Linked to Modest Reduction in Obesity-Related Cancer Risk
GLP-1 receptor agonists showed promise in lowering obesity-related cancer risks in adults with type 2 diabetes, particularly colorectal cancer.
Alzheimer's Association, Senate Champions Refute HHS Secretary Kennedy's Misinformation Head On During Tense Budget Hearing
Senate hearing reveals tensions between scientific consensus and HHS Secretary Kennedy's claims on Alzheimer research funding and priorities.
IV Ibuprofen Cuts Postop Opioid Use by 23% in Older Adults, Study Finds
The opioid-sparing IVIB pain management strategy in adults aged 60 and older was effective in the immediate post-surgical period and associated with limited AEs.
Telehealth Reduces Antibiotic Use for Pediatric ARTIs in Primary Care: Daily Dose
Tailoring Weight Management Conversations Across a Woman’s Lifespan
Johanna Finkle, MD, outlines how clinicians can adapt weight management counseling during key stages of a woman’s life, from preconception through menopause.
FDA Advisory Panel Recommends Continued Use of Monovalent JN.1 Strain for COVID-19 Vaccines
FDA panel endorses continued use of monovalent JN.1 strain for COVID-19 vaccines, aligning with global health recommendations amid evolving variants.
Novel 5-HT2A Agonist GM-2505 Achieves 94% Remission Rate in Phase 2a MDD Trial, With Rapid and Durable Efficacy
The novel rapid-acting psychedelic agent produced antidepressant effects within 24 hours after the first infusion, with a -18.5 point change in MADRS from baseline.
Telehealth May Represent Up to 30% of US Medical Visits by 2026
Telemedicine's trajectory depends far more on future regulatory action than on health care's readiness or patient desire, according to a new report.
Dupilumab for Severe COPD Shows Efficacy, Tolerability, Patient Satisfaction in New Real-World Study
Dupilumab significantly reduced COPD exacerbations and received high satisfaction ratings from patients with severe disease and Th2 inflammation.
FDA Clears First At-Home Pap Smear Alternative for Cervical Cancer Screening: Daily Dose
Combined Oral Contraceptive Use May Triple the Risk of Cryptogenic Stroke in Young Women
ESOC 2025: New research reveals that combined oral contraceptive use significantly increases the risk of cryptogenic stroke in young women, urging careful assessment by clinicians.
Mepolizumab Approved as First Biologic to Treat COPD with Eosinophilic Phenotype
Mepolizumab, an IL-5 inhibitor targeting Th2 inflammation characterized by elevate serum eosinophil count, fills a treatment gap for ~70% of adults with uncontrolled COPD.
Colonoscopy Completion Up 69% With Patient Navigation Program After FIT: Daily Dose
The Weekly Dose: How Medicaid Policies Impact Postpartum Depression Care
At ACOG 2025, Elizabeth Mollard, PhD, discussed her research on Medicaid PPD screening and coverage policies on PPD diagnosis.
Novel CBD Cream Shows Promise in Protecting Skin from UV-A Damage in First-Ever In-Human Trial
Results showed that a nanoencapsulated CBD cream reduced UV-A–induced nuclear and mitochondrial DNA damage linked to photoaging in human skin.
Moderna Announces Withdrawal of BLA for Flu/COVID-19 Combination Vaccine
Moderna voluntarily withdrew the BLA after consultation with the FDA and will resubmit once it has additional phase 3 efficacy data for its investigational flu shot.
Atopic Dermatitis Burden in Older Adults May Surge by 2050: Daily Dose
From Screening to Support: How PCPs Can Tackle PPD
ACOG 2025: Joy Baker, MD, urged primary care clinicians to screen early, refer confidently, and help change the statistics on maternal mental health.
Dupilumab Improves Asthma Control, HRQoL Regardless of Comorbid Th2 Inflammatory Disease
Data from the global RAPID registry provide real-world support for dupilumab efficacy in youths and adults with uncontrolled asthma and with or without CRS and/or nasal polyposis.
Johanna Finkle, MD, on Approaching Weight Loss Discussions with Reproductive-Aged Patients
ACOG 2025: Johanna Finkle, MD, shares strategies to start weight conversations with patients and build clinician confidence in counseling and treatment options.
FDA Narrows COVID-19 Vaccine Access to High-Risk Groups, Demands New Trials for Healthy Adults
The FDA's new approach to evaluating and approving COVID-19 vaccines will move the US away from a one-size-fits-all approach and closer to policy in other countries.
Elinzanetant Effective for VMS Across BMI, Smoking Status: Daily Dose
PPD Screening, Medicaid Coverage, and Access to Care: A Q&A with Elizabeth Mollard, PhD
ACOG 2025: Elizabeth Mollard, PhD, discusses her research on how Medicaid policies influence postpartum depression screening rates.
