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AI-Assisted Mammography Boosts Breast Cancer Detection by 29% in Large Study
Results from the MASAI clinical trial also showed that AI-assisted screening reduced screen-reading workload without increasing the rate of false-positives.
FDA Approves Monthly Lecanemab for Early-Stage Alzheimer Disease: Daily Dose
Your daily dose of the clinical news you may have missed.
Optimizing PTSD Treatment: The Role of Brexpiprazole and Sertraline in Future Guidelines
Brexpiprazole and sertraline showed promise for PTSD treatment in a recent study. Lead author, Lori Davis, MD, discusses clinical findings, treatment guidelines, and future research directions.
COVID-19 Associated with Higher Long-Term Mortality Than Flu or RSV: New Data
Researchers found that COVID-19 had a higher long-term mortality than influenza and RSV in veterans—underscoring vaccination’s vital role.
Stool Tests Still Top Choice for CRC Screening: Daily Dose
7 Drugs Approved for Primary Care: Q4 2024
An oral antibiotic for drug-resistant UTIs, a long-awaited therapy for congenital adrenal hyperplasia, and more.
Propranolol May Lower Stroke Risk in Women with Migraine, Study Finds
Data set to be presented at ISC 2025 shows that the protective effect of propranolol was stronger for ischemic stroke compared to other stroke types.
FDA Approves First Monotherapy Standalone MDD Treatment: Daily Dose
Axsome Therapeutics: FDA Approves Symbravo for Acute Treatment of Migraine
A single oral dose of Symbravo provided rapid migraine pain freedom and return to normal functioning within 2 hours, and sustained efficacy through 24 and 48 hours.
Investigational RSV Antiviral Treatment Reduces Viral Load in Phase 2 Human Challenge Trial
The study of S-337395 showed an 88.9% reduction in RSV viral load and symptom improvement in the highest dose group, with no severe adverse events reported.
Tool Predicts Age at Cognitive Impairment, Dementia Onset: Daily Dose
PTSD Treatment Advancements: Brexpiprazole-Sertraline Offers New Hope in Phase 3 Trial
Data showed that brexpiprazole plus sertraline significantly improved PTSD symptoms vs sertraline alone. Lead author, Lori Davis, MD, discusses more.
FDA Grants Breakthrough Device Designation for Alzheimer Disease Blood Test
The Access p-Tau217/β-Amyloid 1-42 plasma ratio blood test is designed to help identify patients with amyloid pathology associated with AD.
High-Dose Semaglutide Linked to Increased Weight Loss: Daily Dose
FDA Approves New Indication for Semaglutide (Ozempic) to Lower Kidney Risks in Type 2 Diabetes, CKD
This newest approval established Ozempic as the most broadly indicted GLP-1 RA in its class.
Bariatric Surgery Lowers Risk of Liver Complications in Patients with Cirrhosis, Obesity
Metabolic surgery reduced major adverse liver outcomes in people with compensated cirrhosis and obesity by 72%, according to new data.
AI Model Identifies Women with Subjective Cognitive Decline During Menopause: Daily Dose
CVD Remains Leading Cause of Death in US: AHA 2025 Statistical Update
Cardiovascular disease is still the leading cause of death in the US, driven by rising rates of obesity, diabetes, and hypertension, according to new report.
Minimally Invasive Esophageal String Test Used to Monitor Eosinophilic Esophagitis in Children
Researchers at Phoenix Children’s Hospital conducted one of the largest real-world clinical evaluations of the esophageal string test in children.
FDA Approves Mirikizumab for Crohn Disease: Daily Dose
Colorectal Cancer: Investigational Blood Test Shows Promise for Early Detection
ASCO GI Cancers Symposium: The Freenome blood-based test identified nearly 80% of individuals who had colorectal cancer.
Novo Nordisk’s Amycretin Achieves Up to 22% Weight Loss in Phase 1b/2a Trial
Weekly subcutaneous injections of amycretin featured a safety profile similar to other incretin-based drugs, according to new topline results.
Continued Use of Blarcamesine May Slow Cognitive Decline in Alzheimer Disease: Daily Dose
New Study Suggests Patient Benefit Index Complements Traditional Psoriasis Outcome Measures
Findings showed that improved skin clearance and reduced anxiety and depression significantly influenced perceived patient benefit.
Sen-Jam Pharmaceutical Reports Preliminary Phase 2 Results for SJP-002C in COVID-19 Treatment
The novel therapeutic demonstrated a strong safety profile and showed efficacy in reducing symptoms during the early stages of treatment.
Elinzanetant Found Safe, Effective for VMS Linked to Breast Cancer Treatment: Daily Dose
Hypertension Management in Patients with Obesity: 3 Pearls for Primary Care
Caissa Troutman, MD, shares 3 key strategies for managing hypertension in patients with obesity in primary care.
Prioritizing Blood-Based CRC Tests May Lead to Higher Costs and Worse Outcomes, Study Finds
Annual colorectal cancer screening with FIT was the most cost-effective strategy among patients with low adherence, researchers reported.
FDA Approves First Generic Daily GLP-1 Injection for Type 2 Diabetes: Daily Dose
Novel Tool Predicts Onset Age of Cognitive Impairment and Alzheimer Dementia
The Florey Dementia Index showed robustness across different cohorts but more testing is needed, researchers reported.