Editor of Patient Care Online.
Managing Vasomotor Symptoms of Menopause: A Topline Comparison of Treatments
Medical and nonpharmacologic treatment options for VMS range in efficacy and risk/benefit profile; a short slide show offers a topline look at how many compare.
A Half Dose of Semaglutide Yields Weight Loss Equivalent to Clinical Trial Doses in Combination with Online Support Program
Semaglutide dosing was individually tailored for adults with obesity and supported with app-based coaching on diet, physical activity, and other lifestyle factors.
FDA Clears STS101 Nasal Powder for Acute Treatment of Migraine: Daily Dose
Your daily dose of the clinical news you may have missed.
FDA Approves First At-Home Pap Smear Alternative for Cervical Cancer Screening, from Teal Health
The Teal Wand allows women to collect a vaginal sample in the privacy of their home and, according to Teal Health, the test has 96% accuracy for cervical precancer.
Tirzepatide Demonstrates Greater Weight Loss Than Semaglutide in Head-to-Head Study
Full results from the SURMOUNT-5 trial showed tirzepatide achieved 20.2% mean weight loss vs 13.7% with semaglutide in adults with obesity or overweight.
Novel TK1 Inhibitor Demonstrates Rapid, Dose-Dependent Efficacy in Atopic Dermatitis in Ph 1 Trial
Adults receiving the highest dose achieved 2 times the reduction in EASI scores vs placebo with responses emerging as early as day 8 of treatment.
Genetic Risk Score Identifies Individuals Likely to Report Adverse Events from GLP-1 Mimetic Therapy
The ability to predict which individuals will experience adverse events from GLP-1 therapy has great promise for more personalized treatment and improved clinical trial design.
Tirzepatide Associated with Improved HF Symptoms, Renal Function in People with Obesity, CKD: Daily Dose
LEO Pharma Announces Positive Preliminary Phase 2b Findings for Temtokibart in Atopic Dermatitis
The IL-22FA1 antagonist achieved positive outcomes for the primary endpoint based on percentage change in EASI from baseline to week 16 for 3 highest doses, according to LEO.
Crinecerfont Reduces GC Dosing, Improves Androstenedione Levels Across Multiple Pediatric Subgroups
Data for GC reduction and improved A4 levels were consistent across subgroups stratified by sex, race, age, BMI, and baseline A4 levels, according to Neurocrine Biosciences.
Immunogenicity of Combined Flu/COVID-19 Vaccine Noninferior to Components in Older Adults
The investigational mRNA-1083 vaccine induced superior immune responses against all 4 flu strains in adults aged 50-64 years and against 3 in adults 65 and older.
Aprocitentan Reduces Blood Pressure in Black Adults with Resistant HTN: Daily Dose
Rising Lp(a) Levels Increase Risk of Subsequent CVD Events in Adults with ASCVD, According to Large Real-World Study
Any increase in lipoprotein(a) levels was linked to increased risk of myocardial infarction and stroke; women and Black adults are most likely to be affected.
GLP-1 Agonists May Preserve Muscle Mass During Weight Loss: Daily Dose
Weekly Dose: A Roundup of Top Stories for Primary Care Physicians
PODCAST: Listen to our first episode for new research on bacterial vaginosis, a new treatment option for chronic urticaria, and more.
Machine Learning Model Effectively Predicts Depression Risk in Adults with COPD
The model demonstrated 70.63% accuracy for predicting depression, a common comorbidity seen in COPD and one that increases risk for negative outcomes.
RSV Vaccine Uptake Low Among Eligible Populations: Daily Dose
Fremanezumab Demonstrates Dual Benefits in Adults with Migraine and Depression
New data from UNITE study suggest fremanezumab was effective in alleviating migraine and comorbid MDD in patients with both conditions.
Stool-Based Testing for Colorectal Cancer Screening is On the Rise: Expert Perspective with Mark Fendrick, MD
The increase in stool-based CRC testing is a logical trend, Hendrick said in an interview, given the convenience plus the 2 million younger adults now eligible for screening.
Stark Regional Disparities in US Life Expectancy Trends Revealed in Comprehensive Birth Cohort Analysis
Life expectancy increased steadily in the US West and Northeast across the 20th century, but gains were just minimal in Southern states, according to the findings.
Pertussis: A Brief Backgrounder for Primary Care
Cases of whooping cough in the US more than doubled in 2024, and 2 infants have died from the infection. Here is background on the infection and vaccine.
One in 5 US Adults Chooses Against Handwashing, Some Citing it as "Unnecessary," National Survey Finds
While 20% of US adults choose not to wash their hands at appropriate times, nearly half admitted to forgetting to do it, according to a new national survey.
Tirzepatide Switch Outperforms Dulaglutide Dose Escalation in T2D: Daily Dose
Clinically Validated Blood Test Identifies Preeclampsia Risk Early in Pregnancy, New Study Shows
A simple RNA-based blood test can identify the risk of hypertensive disorders in pregnancy months before symptoms appear, researchers reported.
Dupilumab Approved for Uncontrolled Chronic Spontaneous Urticaria: Daily Dose
New Data on Dupilumab Reinforces Its Impact on Chronic Respiratory Diseases
New clinical trial findings to be presented at ATS 2025 highlights the effectiveness of dupilumab in treating COPD and asthma.
Millions of US Adults Have Multiple Forms of Eczema, Study Finds
Nearly 1 in 10 US adults have eczema, with 18% experiencing multiple eczema conditions, researchers from the National Eczema Association reported.
Low-Dose Colchicine Shrinks Plaque Volume in CAD: Daily Dose
Perceived Stress Tied to Worsened Respiratory Outcomes, Decreased QoL in Adults with COPD
Researchers reported higher levels of perceived stress were associated with worse respiratory outcomes, particularly among individuals with severe COPD.
Novel Study Will Monitor Brain Activity, Daily Function in People with Borderline Personality Disorder
Researchers will study brain activity and daily function in patients with BPD using wearable EEG and digital cognitive tools in a first-of-its-kind real-world study.
