Editor of Patient Care Online.
Donanemab Label Revised: New Dosing Schedule Approved for Early Alzheimer’s Treatment
The adjusted dosing for donanemab in early AD reduced ARIA-E risk by 41% compared to the original dosing, without compromising efficacy.
Quest Will Offer FDA-Cleared Fujirebio Blood Test to Detect Alzheimer Disease
The Fujirebio in-vitro diagnostic has shown positive and negative predictive values of 92% and 97%, respectively, for early AD detection and will be offered by end of summer.
GLP-1 Therapy for Obesity Requires Substantial Nutritional Framework, Multidisciplinary Support, Joint Advisory Warns
GLP-1 medications are transforming obesity medicine but strong evidence points to a need for integrating nutrition and lifestyle support for lasting weight loss and health benefits.
Unnecessary Cancer Screenings in the US Persist Long After Guidelines Shift: Daily Dose
Your daily dose of the clinical news you may have missed.
Monu Khanna, MD: Practical Pain Management Tips for Patients with Obesity
Dr Khanna discusses dosing challenges, metabolic issues, and potential complications from medications like acetaminophen.
The Weekly Dose: Clinical Updates on Cancer Detection, Cognitive Screening, CVD Prevention, Atopic Dermatitis Treatment
Discover essential clinical insights on Alzheimer disease screening in primary care, eczema treatments, and the latest in cancer detection and diet impacts on CHD risk.
New Data at IAS 2025 Underscore Real-World Success of Long-Acting Injectable HIV Therapies
New findings showcase the transformative impact of long-acting injectable therapies for effective HIV treatment and prevention.
5 Fall Prevention Tips for Your Older Adult Patients: Refresher for Primary Care
Exercise and strength/balance training are keys to protecting against falls, but careful assessments at each clinic visit may uncover other risks to address.
Body Fat Percentage Outperforms BMI in Predicting Mortality Risk in Young Adults: New Findings
Body fat percentage and waist circumference were both significantly associated with 15-year all-cause mortality while BMI had no significant association.
Obesity and Type 2 Diabetes: Expert Shares 4 Pillars of Management
Caissa Troutman, MD, discusses how clinicians can tailor management plans to reduce risk of developing T2D in patients with obesity.
Clinic- and System-Level Factors Drive Racial Disparities in COVID-19 Antiviral Prescribing, Study Finds
A new study found racial disparities in COVID-19 antiviral prescribing, with clinic site, test type, and telehealth use explaining up to half the gap for Black and Latino patients.
Intranasal COVID-19 Vaccine Found Safe and Immunogenic in Open Label Phase 1 Clinical Trial
Among recipients of high-dose CVXGA, relative vaccine effectiveness was 67.8% against symptomatic COVID infection at a median 7.3 months post-vaccination.
Novel GLP-1/GLP-2 Agent Reduces Body Weight by Up to 8.3% in Phase 1b Obesity Trial
ADA 2025: Dapiglutide showed promising safety and weight loss results in a phase 1b trial, targeting obesity and inflammation with once-weekly dosing.
Apogee Hopes Raised by Phase 2 Data for APG777 to be a Best-In-Class for Atopic Dermatitis
The investigational IL-13 inhibitor showed topline EASI-75 of 66.9% and reduced injection frequency in part A of the APEX phase 2 clinical trial.
Fad Diets and TikTok Nutrition Influencers: 90% of Clinicians Are Concerned, Survey Says
Social media support for the Keto diet and raves about the next best dietary supplement worry HCPs; they also feel their own nutrition education is subpar.
Real-World Weight Loss With GLP-1s Falls Short of Trial Results: Daily Dose
Long-Term Data Support Roflumilast Cream for Pediatric Atopic Dermatitis: Daily Dose
Mental Health Burden in Atopic Dermatitis: Study Identifies Key Risk Factors for Anxiety and Depression
Depression and anxiety affect as many as 1 in 4 people with AD, with pruritus, sleep disorders, education level, and comorbidities identified as independent risk factors.
Circulating Inflammatory Cells Persist in Severe Asthma Despite Biologic Therapy, Study Shows
Research from the Karolinska Institute reveals that therapies such as dupilumab and mepolizumab may not eliminate Th2 lymphocytes, raising concerns about long-term remission.
FDA Backs Shield Test for Broad Early Cancer Screening: Daily Dose
Phase 2b Study of Psychedelic BPL-003 Shows Rapid, Persistent, and Significant Improvement in Treatment Resistant Depression
A single dose of BPL-003 was associated with improved MADRS scores as early as day 2 that were durable through week 8; phase 3 planning is anticipated.
Majority of Americans (8 in 10) Support Routine Childhood Vaccine Requirements, According to New Harvard Poll
As authorities record data on the largest US measles outbreak in decades, 79% of Americans support school vaccine mandates for children, an encouraging result.
Mayo Clinic AI Tool Allows Rapid, Precise Identification of 9 Types of Dementia From Single Brain Scan
The StateViewer clinical decision support system could help expand access to specialist-level insights in clinics that lack neurology expertise, according to researchers.
8 Common Myths About Chronic Back Pain, Plus 8 Facts That Refute Them
Back pain is more common in the US than homeownership, but despite the prevalence, myths persist regarding origins, treatment, and prevention. Here are 8 of them.
SDOH May Affect Use of Menopausal Hormone Therapy: Daily Dose
Nonvaccine Seasonal Flu Preventive Shows Promise in Phase 2b Clinical Trial: Cidara Therapeutics
CD388, an investigational nonvaccine antiviral, demonstrated efficacy up to 76% against influenza in a cohort of more than 5000 healthy, unvaccinated adults.
Adjuvanted Vaccine Against RSV Associated with Substantial Reduced Risk of Dementia
The adjuvanted RSV vaccine, in particular, was associated with a 29% reduction in the risk of dementia in the subsequent 18 months, a University of Oxford study found.
Moderna's mRNA-1010 Flu Vaccine Proves Superior Efficacy in Pivotal Late-Stage Trial
The vaccine showed superior relative vaccine efficacy that was 26.6% higher than a licensed standard-dose influenza vaccine, Moderna reported.
Survey Finds People with Atopic Dermatitis Want Better Symptom Relief: Daily Dose
First Patient Receives Lipocene's LPCN 1154 for Postpartum Depression in Phase 3 Clinical Trial
Lipocene anticipates the phase 3 trial data will support an NDA submission for LPCN 1154 to treat PPD in mid-2026, the company said.
