Cumulative Load of Systolic BP May Better Predict CV Risk in T2D Patients vs Standard BP Measures
In patients with type 2 diabetes, for every standard deviation increase in cumulative SBP load there was an increase of at least 10% in CV risk, a new study found.
The "Ugly Face" of Long COVID: A Conversation with Steven Flanagan, MD, President-elect, AAPM&R
The American Academy of Physical Medicine and Rehabilitation is a leading voice in the campaign for a national plan to address long COVID.
Early-onset Type 2 Diabetes Linked to Significantly Increased Risk for CVD in Later Life: Study
A 5-fold greater risk for all-cause or CVD-related death in persons diagnosed with T2D before age 40 years should be a call to action for enhanced screening, study authors state.
Decline in Physical Function Independently Associated with CVD Risk in Older Adults: ARIC Analysis
Physical performance scores used as a proxy for function in adults aged >65 years improved CVD risk prediction beyond traditional risk factors, study authors report.
Artificial Sweetener Intake Linked to Increased Risk of CVD in Large, Population-based Analysis
Artificial sweeteners should not be considered a healthy and safe alternative to sugar, caution French investigators.
Hypertension Treatment is Cost-effective for CVD Prevention, Whether the Target is from ACC/AHA or JNC 7, Study Reveals
Reducing blood pressure to 140/90 mm Hg or 130/80 mm Hg in high-risk patients proved either cost-saving or cost-effective at 10 years in a simulation study.
Education on Use of ABPM Data Needed in Primary Care to Avoid Misdiagnosis of Hypertension
AHA Hypertension 2022. Half of patients with newly elevated BP had white coat HTN yet some were diagnosed with HTN at next primary care visit, new study finds.
DASH Diet, Weight Loss, Exercise and Other Nondrug Strategies to Manage Hypertension
Find out how effective these 3 and 5 additional ACC/AHA-recommended non-drug interventions are at reducing BP (in mm Hg) in adults with hypertension and with normal BP.
High HDL-C Increases CV Risk in Men with Hypertension, Study Finds
In patients with hypertension, HDL-C >80 mg/dL was linked to a greater risk for CV events among men but not among women. Protective?
FDA Authorizes Pfizer and Moderna Updated COVID-19 Booster Shots
The FDA EUA amendments for updated booster vaccinations are based on clinical studies of the omicron BA.1 variant and preclinical data on the BA.4 and BA.5 variants.
Polypill Reduces Risk of MACE in Secondary Prevention for Older Adults: Results from SECURE
Taking a 3-drug polypill (aspirin, ACEi, statin) vs each of the drugs separately reduced risk for a major CV event by 33%, according to results of the SECURE trial.
The Future of US Antimicrobial Resistance is in Our Hands and There is Work to Do
Steer clear of antibiotic Rxs whenever possible, says Anne Meneghetti, MD, to help the US get back to pre-COVID levels of antimicrobial stewardship.
8 Key Drivers of Hypertension Control & How to Improve Them
These 8 drivers of BP control reflect study of high-performing health systems and the strategies that have led to successful large scale hypertension management.
Primary Care Can Help Restore US Antibiotic Stewardship, Starting with Flu Shots
Preventing viral infections with vaccination can keep the most vulnerable out of the hospital, reducing the risk of bacterial superinfections.
Superinfection Rate in Hospitalized COVID-19 Patients was Found to be Low
Only 9% of inpatients with COVID-19 had a bacterial superinfection that could be treated with antibiotics which curbed use of broad-spectrum antimicrobials.
Pfizer Reports Positive Topline Phase 3 Data for Bivalent RSV Vaccine in Older Adults
Pfizer announced that a single dose of the vaccine, RSVpreF, demonstrated 85.7% efficacy against severe disease, defined by ≥3 symptoms.
Antimicrobial Resistance During COVID-19 Gained New Ground: Expert Perspective
Widespread antibiotic prescribing in the first year of the pandemic set back US progress on the fight against antimicrobial resistance, says Anne Meneghetti, MD.
Novel Rapid-acting Treatment for Major Depressive Disorder First to Get FDA Nod
The dextromethorphan HBr-bupropion HCI combination uses the first new oral MOA in 6 decades and is labeled to improve depressive symptoms starting at 1 week.
Diagnoses of Youth-onset Type 2 Diabetes Spiked by 77% During First Year of COVID-19
Youth newly diagnosed with T2D also were metabolically sicker, with higher HbA1c, serum glucose levels, and BMI at presentation.
Three Flu Season Imperatives: Vaccinate the Young, the Old, and Everyone in Between
Influenza season in the southern hemisphere is "substantial," says Dr William Schaffner. To prepare: "Vaccinate, vaccinate, vaccinate!"
USPSTF Updated Guidance on Statin Use in Primary CVD Prevention Similar to 2016 Recommendations
The recommendations guide initiation of statin therapy in persons aged ≥40 years without a history of CVD and no current signs/symptoms of CVD.
COVID-19, Flu, or Both—There are Always Patients on the Fence
The patients on the vaccine fence are the ones that take the extra time and, over time, an added measure of patience for the clinician.
Moderna Requests Emergency Use Authorization for COVID-19 Bivalent Vaccine
Moderna filed with the FDA for emergency use authorization of a 50-µg dose of a BA.4./BA.5 Omicron-targeting bivalent booster vaccine for those aged ≥18 years.
New Novo Nordisk Combination Rx Better than Components for T2D, Weight Loss
Phase II clinical trial shows a fixed dose combination of semaglutide/cagrilintide reduces HbA1c and weight much better than either drug alone.
Vegetarian Diet May Up Risk for Hip Fracture in Women
Among more than 26 000 women, a vegetarian diet was associated with a 33% greater risk of hip fracture vs diets that included fish or meat.
US Vaccine Fatigue May Harbor Some Unrealistic Expectations
Vaccine fatigue in the US, says Vanderbilt University's William Schaffner, MD, is plentiful for vaccines that are are good—but not perfect.
Don't Call them "Boosters" Anymore and Other COVID-19 Vaccine Recommendations
Let's call the next round of COVID-19 shots "updated vaccines," and help the public understand the true role of this vaccination, says NFID's Schaffner.
William Schaffner, MD: "If It's Not Flu and It's Not COVID, It's Probably RSV"
Respiratory virus season is top of mind for Schaffner, medical director of the National Foundation for Infectious Diseases, and he says it's going to be a challenge.
COVID-19 Vaccine Risk Presented in Context Could Improve Uptake
Pair the risk of side effects associated with a COVID-19 shot with the risk of death in a car accident and see what happens. It worked in this study.
Gout Found More Prevalent among Black Adults in Nationally-representative Population
Racial disparities in gout prevalence could be explained by diet, social determinants of health, kidney disease, and other factors that suggest interventions.