Apixaban May Be More Effective vs Warfarin in Patients with VTE Who Need Extended Anticoagulation
The direct oral anticoagulant was associated with a lower rate of rehospitalization for VTE among patients extending anticoagulation beyond 90 days, investigators report.
Even Modest Alcohol Consumption Found Linked to Decreases in Brain Volume
Increasing alcohol intake from 1 to 2 drinks per day was associated with brain changes equivalent to aging 2 years, according to a study of more than 36 000.
Atogepant: Pivotal Phase 3 Study Meets Primary Endpoint for Preventive Treatment of Chronic Migraine
Findings for atogepant from the phase 3 PROGRESS study will form the basis of a submission by AbbVie to FDA for a label expansion in the US.
Migraine Management Pearls for Primary Care with Neurologist Jessica Ailani, MD
Consider migraine screening for all women aged 20 to 50 years, suggests Ailani; you'll likely find a majority of them have migraine. More pearls follow.
Migraine-specific Preventive Therapies Can Be a Primary Care Tool, Leading Investigator Says
Migraine-specific preventive therapies should be in the primary care toolbox, according to headache specialist Jessica Ailani, MD.
Migraine Perspectives with Jessica Ailani, MD: Start Migraine Care in Primary Care
Migraine headache specialist and researcher Jessica Ailani, MD, fully supports primary care as the setting for the majority of the treatment for the disease.
Routine Point-of-Care Screening for Afib in Primary Care May Be Most Useful in Oldest Adults
Routine point-of-care AF screening in primary care using a handheld ECG device proved feasible but increased diagnoses only in patients aged ≥85 years, in the VITAL-AF study.
CDC: Uptake in Flu Vaccination is Down in Groups at High Risk for Complications
Drops in flu vaccine coverage this season have been recorded among young children and pregnant people and racial/ethnic gaps in uptake continue, says CDC.
Tezepelumab Significantly Reduced Exacerbations in Patients with Severe Asthma, Respiratory Comorbidities
Tara Carr, MD, led a post hoc analysis of the NAVIGATOR phase 3 trial and presented data on tezepelumab efficacy in the vulnerable subgroup at the AAAAI 2022 meeting.
Unmet Needs in US Migraine Headache Management: OVERCOME Study First Data
Findings on use of acute and preventive migraine therapy continue to reveal gaps with far more patients eligible than the proportions using either type.
CGM-measured Glucose Variability Associated with Diabetes Micro- and Macrovascular Complications
Glycemic variability and low time in range were associated with retinopathy, nephropathy, neuropathy, and CVD in a cohort of more than 20 000 persons, most with T2D.
Acute Migraine Treatment: A Guide to Medication Options
When choosing a migraine treatment for acute attack relief, the American Headache Society suggests following these steps.
Novel Agent for Severe Asthma Halves Exacerbation Rates Across Respiratory Comorbidities
Tezepelumab, a TSLP inhibitor, reduced asthma exacerbation rates in patients with severe uncontrolled disease across a range of respiratory comorbidities.
Asthma May be Linked to Severe COVID-19 but Not to Risk for Hospitalization
Patients with asthma who did require hospitalization for SARS-CoV-2 infection were at greater risk for intubation and remdesivir treatment, a new study reports.
FDA Grants Empagliflozin Broad Heart Failure Indication
The landmark approval for the SGLT-2 inhibitor will open access to treatment for the ~ 3 million adults with heart failure with preserved ejection fraction.
Regular Use of Acetaminophen May Significantly Increase Hypertension and CV Risk
In the PATH-BP study, use of acetaminophen 4g/day increased BP among patients with hypertension by nearly 5 mm Hg within 2 weeks of beginning the regimen.
FDA Grants Clearance to First Smartphone App for Programming Insulin Dosing
t:slim X2 insulin pump users can now program or cancel bolus dosing with the secure t:connect mobile app already on their phones, says Tandem Diabetes Care.
Racial/Ethnic Bias Found in Asthma Clinical Trials Used to Update NHLBI Guideline
In the majority of studies that reported racial/ethnic data, White participants were highly overrepresented and Black/Hispanic/all Other underrepresented.
In Patients with T2D and ASCVD, Prescriptions for Evidence-based Therapies Far from Adequate
US patients at high CV risk do not receive adequate evidence-based pharmacotherapy, according to large multisite cohort analysis.
After COVID-19, Risk Increases for Wide Range of Mental Health Disorders
Among persons who survived COVID-19, a new study found a 60% increased risk for any new mental health diagnosis during the year following infection.
Hypertension Toolkit for Primary Care Practice: A Heart Month Checklist
Recommendations on hypertension management from the US Surgeon General's office are summarized for at-a-glance American Heart Month reading.
2022 Opioid Prescribing Guideline Update Open for Public Comment, says CDC
The CDC is inviting public feedback on updated recommendations for opioid prescribing for the first time since the controversial 2016 iteration.
Diabetes Care & Education Specialists, ADA Update National Standards for Diabetes Self-management Education and Support
The 2022 DSMES National Standards update focuses on reducing administrative burden on educators and improving person-centered care for patients.
US States Ranked by Life Expectancy in National Vital Statistics Report
The 50 states and DC are ranked by longest and shortest life expectancy at birth and at age 65 years and by the difference in life expectancy between men and women.
FDA Approves Eversense E3 CGM System for Use up to 6 Months
The 180-day sensor life doubles the period of continuous use and cuts in half the number of CGM removals and reinsertions, without loss of accuracy.
Relapse After Smoking Cessation is High Among Stroke, TIA Survivors: New Findings
The 5-year cumulative relapse rate among early quitters was nearly 40% in a large international cohort of stroke patients, according to an abstract presented at ISC22.
Obesity Common Among Adults Aged <50 Years with Acute Ischemic Stroke, Study Finds
Nearly two-thirds of persons aged younger than 50 years who had an acute ischemic stroke had obesity in a study presented at the 2022 International Stroke Conference.
Prior Authorization Process Could Threaten Patient Outcomes: AMA Survey
Prior authorization-related delays in care have led to serious patient outcomes, including hospitalization, disability, even death, said one-third of physicians surveyed.
Risk for Diabetes in Older Women Reduced by 12% with 2000 Steps per Day: Study
Higher daily step counts by women aged ≥65 years was associated with reduced risk for incident diabetes, an effect that was modified by the level of stepping intensity.
Blood Glucose Levels in T2D: 42 Factors that Make A Difference
These 42 factors that affect blood glucose are listed in categories including food, activity, and biological influences. Perfect information to share with your patients with T2D.