RSV Mortality Higher than for Influenza B 90 Days After Hospital Discharge: New Data
Older adults hospitalized with RSV were older, more frail, and more likely to have respiratory comorbidities than those with influenza A or B, the study found.
What do Patients Want from Telehealth?
Telehealth offers convenience, saves time, and offers other benefits over office visits, but many people don't even know it's available to them, a new survey found.
FDA Approval of Dupilumab for Uncontrolled COPD will Change the Treatment Landscape: Interview with Surya Bhatt, MD, MSPH
Surya Bhatt, MD, MSPH, is coprincipal investigator for the 2 pivotal phase 3 clinical trials that supported today's landmark FDA approval of dupilumab for COPD.
Dupilumab Becomes First Biologic Approved in the US as Targeted Therapy for Adults with COPD
Dupilumab represents the first new treatment approach for uncontrolled COPD in more than a decade and reduced disease exacerbations by 34% in clinical trials.
New Oral Migraine Drugs Less Effective than Triptans for Acute Migraine Treatment
Triptan medications outperformed newer classes of oral migraine drugs, ie, gepants and ditans, on standard measures of efficacy for acute treatment.
Cancer Diagnosis Rates in 2021 Still Lagged Behind Projections Following Pandemic Effects
The decline in cancer diagnoses during the COVID-19 shutdown in 2020 did not lead to an expected compensatory increase in diagnoses in 2021, according to NCI researchers.
Lebrikizumab Demonstrates Sustained Disease Control in Atopic Dermatitis Up to 3 Years
Among adolescents and adults with moderate-to-severe AD, more than 80% achieved sustained disease control, the majority not requiring topical or systemic rescue medication.
Preconception Prediabetes Ups Risk for Poor Pregnancy Outcomes in Young Women: New Data
The risk of gestational diabetes was 2-fold greater among young women with prediabetes before conceiving compared with those who had normoglycemia.
FDA Accepts NDA for Delgocitinib Cream, Developed Specifically to Treat Chronic Hand Eczema
Delgocitinib specifically inhibits activation of JAK-STAT signaling in chronic hand eczema and would be an option for people unable to use topical corticosteroids.
COVID-19 Vaccines 2024-2025: Is America Ready and Willing?
COVID-19 vaccine myths of many types remain potent enough to raise public health experts' concerns about Americans' willingness to roll up sleeves this year.
Real-World Study Supports Use of DermaSensor in Primary Care to Differentiate Cancerous and Benign Lesions
The AI-based point-of-care device outperformed clinician standard of care for sensitivity (90% vs 40%) and had a negative predictive value of 98.9%
Erenumab Induces Remission in Chronic Migraine Medication Overuse Headache
Erenumab 140 mg safely and effectively induced remission in nonopioid MOH within 6 months in individuals for whom other preventive medications had failed.
First-Ever CGM Cleared for 365-Day Use
The only CGM system cleared for 1 year of use in type 1 and 2 diabetes is expected to be available in the fourth quarter of this year, the manufacturers said.
Co-administration of Arexvy and Shingrix Yields Positive Topline Phase 3 Data, GSK Reports
Immune responses for both vaccines were noninferior when given at the same visit compared with separate administration among adults aged 50 years and older.
21 Beliefs about AI in Health Care, from People Like Your Patients
AI is welcomed by US adults for streamlining the administrative complexity of getting medical care but not so much for replacing health care professionals themselves.
A False-Positive Breast Cancer Screening Result Discourages Future Mammography
Those least likely to schedule further screening mammograms had received a false-positive with recommendation for follow-up after only a short interval.
Exact Sciences Debuts Positive Topline Results for Trial of Blood-Based Colorectal Cancer Screening Algorithm
Presented at ESMO, the findings reflect “a highly discriminate blood-based panel of methylated DNA markers” as well as a robust new marker class for identifying patients with precancerous lesions.
Lilly Announces FDA Approval of Lebrikizumab-lbkz for Moderate to Severe Atopic Dermatitis
Among those treated with lebrikizumab, more than one-third saw clear/almost clear skin at week 16; three-quarters of them maintained results at week 52 with monthly dosing.
Investigational PACAP Inhibitor Reduces Monthly Migraine Days, Lundbeck Reports
Individuals with migraine who failed to respond to up to 4 previous migraine preventive treatments saw fewer monthly migraine and headache days after 1 infusion of Lu AG90222.
FDA Approves Dupilumab Label Expansion with Indication for CRSwNP in Adolescents
The approval makes dupilumab available to treat uncontrolled CRSwNP in adolescents aged 12 to 17 years, expanding on the current approved range of 18 years and older.
Awareness of Uncontrolled Hypertension Low, Particularly Among Young Adults, Study Warns
Unawareness was highest among the youngest adults, aged 18 to 44 years, an age range where CV health should be optimized to avoid later morbidity, researchers wrote.
How to Define an Atopic Dermatitis Flare: Survey Seeks New Patient Consensus
The term "flare" is used consistently in discussions of AD, but is everyone talking about the same thing? New research closes in on a patient-centered definition.
GSK mRNA Flu Vaccine Candidate Delivers Favorable Topline Phase 2 Findings, Ready for Phase 3
The GSK reformulation induced acceptable immune responses for both influenza A and B strains, overcoming a setback earlier in the ability to successfully neutralize the latter.
sNDA Goes to FDA for neffy 1 mg for Young Children with Type 1 Allergic Reactions
The needle-free nasal spray, if approved, would be the first new administration method for epinephrine in young children in 35 years.
Congenital Adrenal Hyperplasia Management Across the Lifespan
The cortisol deficiency central to congenital adrenal hyperplasia requires lifelong treatment with distinct shifts in management required at each developmental stage.
RSV Vaccine Proves 75% Effective Against Hospitalization in Older Adults, According to New CDC Data
The new data amend that from prelicensure trials, which did not include fair representation of older adults and others more vulnerable to severe RSV disease.
Novel GLP-1 RA for Obesity Shows Promise in Early Phase 1 Trial
Once-daily oral TERNS-601 was associated with a significant mean 5% weight reduction after 28 days and had a favorable tolerability profile.
CDC COVID-19 Vaccine Bridge Access Program Ends 4 Months Earlier than Planned
The Bridge Access Program allowed Americans who are uninsured or underinsured to receive COVID-19 vaccination at not cost and was ended abruptly last month.
Efsitora Alfa, Eli Lilly’s Once Weekly Insulin, Has Positive Topline Results in Two Trials
Across two clinical trials in the QWINT program, once-wekly efsitora showed comparable A1C reduction to frequently used daily insulins.
The CRF Pathway Interrupted: Potential to Transform CAH Care
A therapeutic strategy that reduces ACTH-driven androgen excess through a glucocorticoid-independent pathway could significantly improve treatment and patient QoL.
