Zonisamide Shows Promise for Hard-to-Treat Migraine in Children, Adolescents
While the data on zonisamide efficacy for migraine in youths is preliminary, all study participants experienced a 66% reduction in headaches after 1 month of treatment.
Measles Claims Life of Unvaccinated Texas Schoolchild, First US Fatality Reported Since 2015
A rural west Texas "undervaccinated" Mennonite community is the epicenter of the worst measles outbreak in the state in 30 years, the state health department reported.
Obesity & Chronic Pain Management: An Expert Discussion
Monu Khanna, MD, discusses challenges in managing pain in patients with obesity, effective pharmacological and nonpharmacological therapies, and more.
Symbravo for Migraine Demonstrates Efficacy Superior to Prior CGRP Inhibitor Treatment in Phase 3 Trial
Symbravo, compared with previous CGRP inhibitor therapy, achieved superior response across efficacy measures including pain freedom and improvements in QoL.
Obesity and Mental Health: Expert Details Interplay, How the Sexes Differ
Shagun Bindlish, MD, discusses the complex interplay between obesity and mental health conditions and how sex is a potential moderating factor.
Sinaptica Announces Enrollment for Phase 2 Clinical Trial in Early Alzheimer Disease of Dual Neuromodulation System
The proprietary combination of 2 neurostimulation modalities deployed simultaneously may enhance efficacy while reducing treatment time by 70%, the company said.
Depression Increases Risk For and Accrual of Long-Term Health Disorders
Comorbid conditions accrued at a rate 30% faster among adults with depression than in those without the disorder over a 7-year follow-up period.
Dupilumab Cardiometabolic Safety in Real-World Study of Atopic Dermatitis Supports Clinical Trial Evidence
Treatment of AD with dupilumab, compared with cyclosporine and methotrexate, was associated with significantly reduced risk of a wide range of CV outcomes at 1 year.
Cancer Rates in Black Individuals Decline but Still Outpace Other Racial, Ethnic Groups, Says American Cancer Society
The outsized burden continues among Black men, a group with prostate cancer incidence rates 67% higher than those of White men and mortality rates more than twice as high.
5 Final Dermatology Tips from the Midwinter Hawaii Dermatology Conference
Tips cover biologic agents and hepatitis B, 5-FU plus calcipotriene for AK, a triple treatment package for post-acne postinflammatory hyperpigmentation, and more.
Problems with Nail Pigment: 3 Cases of a Black Nail
The sudden appearance of "a black nail" can frighten a patient and should be investigated. Nail expert Boni Elewski, MD, shares 3 cases and the outcomes.
Melasma Mitigation: It All Begins with Photoprotection
Susan C Taylor, MD, is internationally recognized for her expertise in dermatologic conditions in skin of color and spoke about avoiding photodamage at the Midwinter Clinical Derm Conference.
Acne and Rosacea Insights: Experts Offer Pearls and Novel Approaches
Established therapies for these common disorders don't always lead to optimal results; experts offer new evidence-based options that may help.
Nailing Treatment of 3 Nail Disorders: Nail Lichen Planus, Psoriasis, and Onychomycosis
Systemic therapy for nail disorders, including biologics and JAK inhibitors, is gaining favor; learn more about early diagnosis and aggressive treatment from an expert.
Late Breakers in Atopic Dermatitis: Highlights and Previews with Alexandra Golant, MD
From the revolutionary approval of dupilumab to the promise of potential disease modification with OX40 inhibitors, Golant provided a wide-ranging update of the treatment space.
More 60 Dermatology Tips in 60 Minutes from the Midwinter Clinical Hawaii Derm Conference
How to treat lichenoid dermatoses, what to do when the Quant Gold is indeterminate, pocket-sized Wood lights, plus 9 more pearls from the experts.
A Case of Biologic Switching in Psoriasis and How to Optimize Outcomes with Ron Vender, MD
Switching biologic treatment for patients with moderate to severe psoriasis, needn't be daunting, Vender said; he works through a tricky case that ended very well.
FDA Approves GSK's Pentavalent Meningococcal Vaccine Penmenvy
The ACIP of the CDC will meet on February 26 to vote on recommendations for appropriate incorporation of Penmenvy into the routine vaccination schedule.
Pearls for Solving Problems when Treating Psoriasis: From the Experts
Dermatology experts share pearls to help when biologics alone are not enough, when obesity is a comorbidity with psoriasis, and when isotype switching derails therapy.
Alopecia Areata: Emerging Data and Treatment Approaches
JAK inhibitors are being used widely and successfully to treat alopecia areata, and Amy McMichaels, MD, showcased data and also discussed patient communication.
The Great Atopic Dermatitis Treatment Debate: Biologics vs JAK Inhibitors
There really is no debate - it's all about individualizing treatment for the patient, but Drs Neal Bhatia and Raj Chovatiya went head to head at Midwinter Hawaii.
60 Tips in 60 Minutes: Day 1 at the 2025 Midwinter Clinical Hawaii Dermatology Conference
The dermatologic tips offered in this short slide show come from 4 renowned professionals and reflect their subspecialties.
10 Dermatology Tips for Primary Care
Cardiovascular Disease Prevention in Patients with Obesity: An Expert Perspective
Anila Chadha, MD, highlights key preventive strategies to reduce CVD risk in patients with obesity and how to tailor them to address individual patient needs.
Atopic Dermatitis Treatments Up Close: Biologics, JAK Inhibitors, and Cytokines, Oh My
Atopic dermatitis management will be the topic of a debate over treatment with biologics and JAK inhibitors and in a focused session on the role of IL-13 in the chronic skin disease.
State Abortion Bans Cause Broad Disparity in Outcomes According to 2 Studies from Johns Hopkins Bloomberg School of Public Health
The 2 analyses of data on fertility and infant mortality were conducted in the first 14 states to impose complete or 6-week bans after the Dobbs decision in June 2022.
The 2025 Winter Clinical Hawaii Dermatology Conference: Saturday Preview
The 2025 Winter Clinical Hawaii kicks off today with the first full day of educational sessions starting tomorrow, February 15 - here's what to look for.
A Perioperative Pain Management Expert Scans His Crystal Ball for the Look of the Practice in 2050
More consistent use of evidence-based guidelines and individualized pain management for every patient lead the hopes Edward Mariano, MD, MAS has for the future.
Dupilumab, Tezepelumab Gain Ground for Severe Asthma but Overall Biologic Adherence Rates Found Low: 2 Studies from 2025 AAAAI/WAO
AAAAI 2025. One study found the 2 newer biologics have been prescribed more frequently while the other suggests asthma treatment may not be optimal or even consistent.
AXS-05 Safety, Tolerability in Major Depressive Disorder Confirmed in Pooled Analysis of GEMINI and ASCEND Trials
Pooled data from the pivotal randomized clinical trials were consistent with prior outcomes supporting early occurrence and resolution of the most common TEAEs.