Perceived Racism Linked to Significantly Increased Risk for Heart Disease in Black Women
Black women who reported perceived interpersonal racism in employment, housing, and interactions with police had a nearly 30% higher risk of CHD than those reporting none.
Perceived Stress Linked to Cognitive Impairment among Older Adults in the REGARDS Study
Screening for stress among older adults who present to primary care with signs of cognitive impairment could be key to reducing risk and targeting intervention, study authors say.
FDA Approves First Intranasal CGRP Receptor Antagonist for Adult Migraine
Zavegepant, the first FDA-approved intranasal CGRP receptor antagonist, could be available in pharmacies by July 2023.
Friday's 5 Quotes for Primary Care 3-10-2023
Each of the quotes is taken from a study reviewed on Patient Care during the week and was chosen for the research team’s passion about the clinical implications of their findings.
This Early Long COVID Clinic Was Led by PM&R and Family and Internal Medicine
The University of Washington in Seattle opened one of the country's first long COVID clinics, staffed by specialists in rehabilitation and primary care.
FDA Accepts sNDA for Empagliflozin for Children with Type 2 Diabetes Aged 10 Years and Older
The SGLT-2 inhibitor, if approved for this age group, would be the first agent in the class with the indication as adjunctive treatment for T2D for those younger than age 18.
Residual Inflammation in Statin-treated Patients Linked to Greater Risk for MACE, Mortality vs Residual Cholesterol
Among patients in the highest quartile of hsCRP, the risks of CV-related and all-cause death were more than 2 times higher than in those in the highest quartile of LDL-C.
A Primary Care Physician and a Physiatrist Share Notes on Sharing Patients
In a multidisciplinary primary care outpatient clinic, PCP Maisterra and physiatrist McMullen confer and refer on a regular basis and patients always win.
Ketogenic Diet Associated with Increased Serum Lipids, 2-fold Greater Risk of MACE
ACC2023. Risk for MACE was nearly 7-fold higher in participants on a keto diet whose LDL-C was already high compared with those on a standard diet with LDL-C in a normal range.
Likelihood of Optimal GDMT for Patients with T2D, ASCVD Increased with Multifaceted Clinic Intervention
ACC2023. For high-risk T2D patients not receiving optimal treatment for hyperlipidemia, hypertension, or hyperglycemia, intensive, multidisciplinary training for clinic staff could shift practice.
Primary Care and Physical Medicine & Rehab: In Conversation
Two clinicians from a multispecialty primary care outpatient clinic in Seattle talk about how they work together and the benefits of sharing their space and their patients.
Post-CABG Risk Remains Higher for Women vs Men with No Change Over Last 10 Years
After coronary artery bypass surgery, women are still at higher risk for MI, stroke, and other adverse events than men despite years of improvement in technique and care.
13 Medications to Avoid in Adults with Hypertension: A Guideline Topline for Primary Care
Reduce potential for promoting or worsening hypertension by stopping, reducing, or using alternatives to these 13 drugs and substances.
Nerivio Prescription Wearable Cleared by FDA for Preventive Treatment of Migraine
The prescription remote electrical neuromodulation device is now cleared for both acute and preventive treatment of migraine in those aged ≥12 years, according to Theranica.
FDA Advisory Committee Votes in Support of Safety, Efficacy of GSK Adult RSV Vaccine Candidate
The VRBPAC vote that the GSK data support the vaccine's efficacy was unanimous and on safety the vote was 10-2. PDUFA date set for May, 2023.
Findings on Food Addiction in Older US Adults Raise Caution Flag for Primary Care
Nearly half of US adults aged 50 to 80 years report at least 1 symptom of addictive eating, a caution flag for primary care according to these experts.
Lilly Announces 70% Reductions in Insulin Prices, Expands Access Program
Some of the insulin price cuts announced will be effective immediately, others will roll out in April and May; Lilly Chair and CEO calls industry and lawmakers to join the effort.
Impact of Air Pollution on BMD Found Double that of Aging in Postmenopausal Women
Nitrous oxides were found to be the most damaging to bone architecture in the first study to look at the pollution-BMD association in postmenopausal women.
Insomnia Associated with Significant Risk for MI, Should be Designated a CV Risk Factor
ACC 2023. A large study found increased risk for MI regardless of age and detected particularly heightened risk among women and persons with diabetes who have insomnia.
Food Addiction: The Influence of Big Tobacco Plus Thoughts on a Role for Weight Management Drugs
Food addiction researcher Ashley Gearhardt, PhD, links survey data on addictive behavior in older adults to the dawn of aggressive food marketing.
FDA Issues EUA for First OTC Influenza-COVID-19 Test Kit
The first-of-its kind combination home-based test matched lab-based PCR tests for identification of influenza A and B and COVID-19.
Air Pollution Linked to Parkinson Disease with Regional Differences, Hot Spots Identified
The association between air pollution and Parkinson disease was found strongest in the Rocky Mountain region and the Mississippi-Ohio River Valley in a new study.
Long COVID Emotional Symptoms Associated with Changes in Brain Structure and Function
Even after mild cases of COVID-19, imaging found evidence of tissue atrophy and aberrant connectivity in persons with long-COVID-related anxiety, depression.
PCP Perspective: Should Primary Care Add Screening for Food Addiction to the To-Do List?
Many older adults show symptoms of food addiction, a new survey found. Is it time to start screening? A primary care physician considers the feasibility and the value.
Tezepelumab Effective in Severe Asthma Cohorts Stratified by Age at Onset, Inflammatory Phenotype, and Allergen Sensitization
AAAAI 2023. The TSLP inhibitor was superior to placebo in 2 post hoc analyses of the PATHWAY and NAVIGATOR clinical trials.
For Persons with Asthma Infected with COVID-19, Systemic Corticosteroid Prescribing is Up
AAAAI 2023. Pandemic prescribing rates for systemic corticosteroids increased from Alpha to Delta to Omicron waves of COVID-19 but hospitalizations have dropped, study finds.
Subclinical Food Addiction Common Among Older Adults, Women Twice as Vulnerable as Men: Expert Interview
Behavioral problems with food were found more common among women in their 50s and 60s and among men and women who report being lonely, in poor health, and overweight.
One in 8 Older US Adults Meet Criteria for Food Addiction: Experts Explain
Yale Food Addiction Scale author Ashley Gearhardt, PhD, and National Poll on Healthy Aging director Jeffrey Kullgren, MD, MS, MPH, highlight new survey findings.
Aspirin Discontinuation at 24-28 Weeks Has No Impact on Preeclampsia in High-risk Patients
The novel findings suggest that continuation of aspirin therapy until gestation week 36 in those at high risk of preeclampsia may not be necessary in all cases.
FDA Accepts Pfizer BLA for Maternal RSV Vaccine for Priority Review
Pfizer will present pivotal phase 3 data for RSVpreF to the ACIP on February 23; FDA has set a PDUFA date for the vaccine candidate of August 2023.