FDA Advisory Group Votes in Favor of Pfizer Investigational Maternal RSV Vaccine Candidate
The Pfizer vaccine RSVpreF administered to pregnant people was judged by the advisory committee to be effective at preventing RSV in infants from birth to 6 months.
First RSV Vaccine Brings "Sense of Relief" to Public Health Experts, Says Immunize.org President
Kelly Moore, MD, MPH, says the public health community is relieved by the FDA's approval and excited at "the chance to finally do something about the disease."
First Opioid Rx Leads to Long-term Use in 1 of 5 with Rheumatic or Musculoskeletal Disorders
Patients with rheumatoid arthritis and fibromyalgia were at the greatest risk of transitioning to long-term opioid use 1 year after a first prescription, a new study found.
FDA Grants Dapagliflozin Label Expansion for Treatment of Full Spectrum of Heart Failure
The label expansion is based on findings from the pivotal phase 3 DELIVER trial in which dapagliflozin reduced the composite CV/HF endpoint in HF patients with HFmrEF or HFpEF.
9 New Studies on Women's Health in Recognition of Women's Health Week 2023
Women's Health Week (May 14-20, 2023) is an ideal opportunity to review the top research, policy shifts, and potential drug approvals that affect your patient panel.
3 Things for Primary Care to Remember About Physical Medicine and Rehabilitation
Scott Laker, MD, vice president of the AAPM&R, offers 3 thoughts on what primary care clinicians should think of when they think about PM&R.
Friday's 5 Quotes for Primary Care 5-12-2023
USPSTF says start mammograms 10 years earlier, OTC contraceptive coming soon, another antiobesity drug in the wings, and 2 more weekly updates of note.
FDA Approves Brexpiprazole for Agitation Associated with Alzheimer Dementia
Brexpiprazole, an atypical antipsychotic, is the first and only medication approved to treat AD-associated agitation, reported in almost half of people with the disease.
Medication Can't Do It All, Says Obesity and Weight Management Expert
Dr Caroline Apovian reminds primary care clinicians who care for patients with obesity that diet and lifestyle counseling are essential for maximum results.
Primary Care and Physiatry: Complementary Tools for Full Recovery from Injury
The partnership between primary care and PM&R is a tool in each specialty's tool box, with the patient's return to full function the shared goal.
Oral Contraceptive Gets Unanimous Recommendation for OTC Use from FDA Advisory Panel
Opill, a progestin-only oral contraceptive, if approved by the FDA, would be the first an only form of birth control in the US available without a physician's prescription.
Investigational Antiobesity Drug from Boehringer Ingelheim Meets Primary Endpoint in Phase 2 Trial
The dual GIP/GLP-1 receptor agonist was associated with a nearly 15% reduction in body weight in adults with overweight/obesity and without type 2 diabetes.
Denosumab Superior to Alendronate for Reduction of Postmenopausal Fracture Risk in Real-world Study
Denosumab reduced RR of fracture vs alendronate across fracture types, eg, by 36% for hip fracture, by 43% for nonvertebral fractures, and by 30% for vertebral fractures.
Concussion Patients are Getting Younger: Bad News, Good News
A diagnosis of concussion in an 8-year-old who plays weekend soccer is, on its face, bad news; the good news is that 15 years ago, it might have gone unnoticed, untreated.
USPSTF: Begin Breast Cancer Screening at Age 40 (Not 50) Years for All Women
The lower recommended starting age for screening reflects rising cancer diagnoses among younger women and persistently high mortality rates among Black women.
Women Underrepresented in Late-breaking Cardiovascular Clinical Trials, a New Analysis Finds
Sex-based disparities found in high-profile clinical trials presented at 3 key cardiology scientific meetings underscore the lack of progress made toward equitable inclusion in research.
Start Low, Go Slow with GLP-1 Receptor Agonists when Initiating Weight Management Therapy
GLP-1 RA side effects such as nausea and vomiting can be minimized by starting at the lowest available dose and titrating slowly; Dr Caroline Apovian explains why.
Antiobesity Medications Complement Lifestyle Change in Chronic Weight Management
GLP-1 receptor agonist-based medications for obesity modify gut hormone imbalances, making diet and lifestyle change far more effective, explains Caroline Apovian, MD.
Novel 1-hour Endoscopic Procedure Could Eliminate Need for Insulin in Patients with T2D
The novel ablation technique which "rejuvenates" critical duodenal mucosa, is followed after 2 weeks by treatment with semaglutide and was both safe and effective.
Medicinal Cannabis Effectively Reduced Cancer Pain, Opioid Use in Large Registry Study
Medicinal cannabis products reduced use of opioids and other medications and products that contained balanced measures of THC and CBD appeared most effective.
Friday's 5 Quotes for Primary Care 5-5-2023
Tirzepatide delivers 15.7% weight loss in adults with obesity; remote intervention increases cancer screening in women; women at greater post-MI risk vs men; plus 2 more updates of note.
Early Conversations about Concussions were Hard: AAPM&R Vice President Scott Laker, MD
The vice president of the American Academy of Physical Medicine & Rehabilitation played a significant role in developing early concussion programs and educating clinicians and coaches.
Donanemab Significantly Slows Cognitive, Functional Decline in Early Alzheimer Disease
Eli Lilly's investigational drug targeting amyloid plaque slowed clinical decline by 35% in participants with early symptomatic Alzheimer disease at 18 months, the company announced.
FDA Approves World's First Vaccine Against Respiratory Syncytial Virus
The novel vaccine, from biopharma company GSK, is approved to prevent RSV-associated lower respiratory tract disease in adults aged ≥60 years.
ACP Announces Intensified Advocacy for Equitable Care of Obesity
The American College of Physicians announced an initiative that renews and expands its focus on equitable access to obesity care, including new resources for physicians.
"Eat, Sleep, Console" Reduces Hospital Stay, Medication Use in Opioid-exposed Neonates
Infants with neonatal opioid withdrawal syndrome cared for using a novel functional approach were discharged nearly 7 days sooner than those treated with usual care.
Remote Intervention Increases 3 Cancer Screenings Among Women in Rural US
A combination of outreach measures tailored to the needs of rural Midwest women increased recommended screenings by as much as 6-fold.
Long COVID Diagnosis & Treatment: Many US Physicians Have Doubts
The US health care provider community continues to do its collective best to cope with the protean condition that is long COVID, according to recent poll findings.
Persistent Changes in Brain Function Observed in Persons with Long COVID
Persons with long COVID showed compensatory neural activity in certain brain areas while performing memory tasks as long as 6 months after infection resolved.
Friday's 5 Quotes for Primary Care 4-28-2023
"Disconnect" on anticoagulation between MDs and patients; NASH resolves after bariatric surgery; antiobesity medications are not weight-loss drugs; plus 2 more updates of note.