July 17th 2025
Merck has launched phase 3 trials for MK-8527, a promising once-monthly HIV prevention pill, aiming to enhance PrEP options globally.
What Are Pleiotropic Effects? The Role of Statins in Decreasing Inflammation
March 12th 2013It would be a mistake to attribute all beneficial outcomes obtained from statins solely to cholesterol lowering. Statins have pleiotropic effects-that is, they are simultaneously capable of producing more than one benefit, and in cardiovascular risk reduction, they accomplish more than simply lowering cholesterol.
HIV/AIDS and Starfish: "It Makes A Difference to This One"
February 20th 2013Millions of years of life have been saved by antiretroviral therapy. For more lives to be saved, for more years of life to be gained, patients and doctors need to be aware of the risk of HIV infection and to be amendable to screening.
Oroesophageal Candidiasis in a Patient With AIDS
January 18th 2013Topical treatment for oral candidiasis is not as effective when there is esophageal involvement. Topical treatments include nystatin, amphotericin B solution, and miconazole tablets. Systemic therapy given orally includes the azoles, of which fluconazole remains the most effective commonly prescribed. Voriconazole is effective against some resistant strains of Candida. Echinocandins, a newer class of drugs, inhibit cell wall synthesis.