What is Precision Neurocognition? David J Libon, PhD, Provides an Overview
Libon, a professor at the New Jersey Institute for Successful Aging at Rowan University, says the refined approach to cognitive assessment is widely available.
World Brain Day 2025: 9 Studies on Alzheimer Disease and Related Dementias Chosen for Primary Care
World Brain Day is celebrated on July 22 every year. In recognition Patient Care has summarized 9 notable studies of key interest to primary care for quick review.
Monu Khanna, MD, on the Unique Role of Primary Care in Managing Cardiometabolic Disease
Dr Khanna discusses how PCPs can use patient relationships to tailor lifestyle advice and manage obesity-related cardiometabolic disease.
Needle-Free Epinephrine Nasal Spray Shows Promise in Pediatric Food Allergy Anaphylaxis
Neffy, a needle-free epinephrine nasal spray, showed promise as a safe alternative for treating anaphylaxis in children with food allergies in a phase 3 trial.
Atopic Dermatitis Flare Frequency May Predict Future Disease Severity, According to New Findings
Atopic dermatitis flares should be factored in to an assessment of disease severity and prognosis, the authors note, and a threshold established for acceptable frequency.
17 Vaccines for Adults: Who to Consider for Each
A review of 4 factors can help primary care clinicians with an initial decision about adult vaccination: health, age, lifestyle, and occupation (HALO).
Roche's Investigational Anti-IL-33/ST2 Antibody for COPD Misses Phase 3 Primary Endpoint
Astegolimab did result in a statistically significant reduction of annualized exacerbation rates in a similar phase 2b trial, but the result was not replicated in phase 3.
FDA Advisory Committee Casts Nearly Unanimous Vote Against Otsuka's PTSD Combination
The FDA advisory committee overwhelmingly voted against Otsuka's PTSD treatment, citing insufficient evidence from clinical trials for approval.
Clinicians Who Tout Use of AI Risk Undermining Patient Trust, Study Finds
Clinicians who advertised use of AI for diagnostic, therapeutic, even administrative purposes were rated poorly on empathy, trustworthiness, and competence.
Digital Asthma Self Management Program Improves Symptom Control But Disparities in Benefit Are Clear
A smartphone-based asthma management program significantly enhanced symptom control, but may require engagement or cultural tailoring to expand the effect.
Shingrix Prefilled Syringe Gets FDA Greenlight, According to GSK
The prefilled syringe presentation streamlines administration of the vaccine, eliminating the need to combine the lyophylized antigen and separate adjuvant.
Phase 3 Trials Begin for Once-Monthly Oral HIV Prevention Pill
Merck has launched phase 3 trials for MK-8527, a promising once-monthly HIV prevention pill, aiming to enhance PrEP options globally.
Digital Latency Measures Refine Early Detection of Cognitive Decline: Expert Review of Evidence
Digital latency measures enhance early detection of cognitive decline, revealing neurodegenerative changes before traditional tests indicate impairment.
Treatment of Neuropathic Pain: A Close Look at a New Meta-Analysis
For the often treatment-resistant pain of neuropathic conditions, the meta-analysis includes updated evidence for both pharmacologic and neuromodulatory interventions.
Otsuka and Lundbeck Will Face Scrutiny Over Investigational PTSD Therapy at July 18 FDA AdComm Meeting
FDA's Psychopharmacologic Drugs Advisory Committee will evaluate the novel brexpiprazole/sertraline combination, weighing efficacy against existing therapies amid mixed trial results.
Pre- and Post-Menopausal Hormone Therapy Has Differential Effect on Breast Cancer Subtypes
Combined estrogen-progestin hormone therapy used to manage VMS of menopause was associated with a higher risk of developing luminal-like breast cancer subtypes and other subtypes.
Monu Khanna, MD, on Why Cardiometabolic Screening Must Start Early in Patients with Obesity
Dr Khanna urges early screening for cardiometabolic risk in patients with obesity and highlights the role of primary care in prevention and education.
Lifestyle Medicine Is at a Tipping Point in the US, Expert Says, and It Could Be Just in Time
Without a shift in the approach to disease prevention and management in the US, the health system won't be able to handle the burden of our morbidity, says Richard Rosenfeld, MD, MPH, MBA.
Weight Loss Achievable Despite Interruptions in GLP-1 Medication Access, Study Finds
ENDO 2025. People with inconsistent access to GLP-1 medications still achieved clinically significant weight loss when therapy was combined with lifestyle changes and coaching.
New Guidelines Recommend Preconception Screening in Diabetes, Universal Testing for Primary Aldosteronism
ENDO 2025: The publications reflect growing consensus that integration of endocrine screening into standard clinical workflows is essential for early risk detection and long-term disease prevention.
Obesity Redefined: 1 in 5 Adults Reclassified Under New EASO Criteria
Individuals newly classified with obesity using the European framework were found to be overall sicker and at greater risk for mortality.
Q&A: GLP-1 Monotherapy Is Not Enough—Jonathan Bonnet, MD, MPH, on the Lifestyle Prescription for Obesity
Obesity medicine expert Bonnet answers questions about the downsides of GLP-1 therapy for obesity management and how lifestyle medicine interventions will help.
"Everyone is a Candidate for Some Positive Lifestyle Change," Guideline Author Suggests
Richard Rosenfeld, MD, MPH, MBA, led the development of lifestyle medicine guidelines to treat or even reverse prediabetes and type 2 diabetes.
Population-Wide Study Finds No Link Between Aluminum Exposure in Vaccines and Childhood Disorders
The Danish study analyzed a nationwide cohort of 2.1 million children and found no association between aluminum exposure and allergic, autoimmune, or neurodevelopmental conditions.
ENDO 2025: Most Patients With Classic Congenital Adrenal Hyperplasia Experience High Glucocorticoid Exposure or Suboptimal Control
A new analysis of the CAHtalog phase 3 study showed approximately 95% of participants experienced either high glucocorticoid exposure or elevated androstenedione levels during treatment.
The Role of Stress Reduction in Cardiometabolic Disease Management for Patients with Obesity
Monu Khanna, MD, discusses the benefits of behavioral strategies, including yoga, breathwork, and dancing, in reducing cardiovascular disease risk in patients with obesity.
Turn Therapeutics Launches First Clinical Trial to Assess Topical IL-36 Inhibitor for Atopic Dermatitis
GX-03 has proven effective in preclinical trials, reducing disease severity by more than 50% vs placebo. Data from the current study are expected by year end.
Maternal Depression Impairs Parental Emotional Responsiveness, Daily Care for Infants, Children: Global Systematic Review
Maternal depression significantly disrupts parenting behaviors, impacting child development and emotional bonding, according to an updated international literature review.
Lifestyle Medicine Guidelines for T2D, Prediabetes Are the Result of Remarkable Collaboration Across Specialties
Lead author for the American College of Lifestyle Medicine's new clinical practice guideline discusses the broad endorsement for the recommendations across participating groups.
Monu Khanna, MD: Essential Lifestyle Changes for Managing Obesity and Cardiometabolic Risk Factors