July 10th 2025
Moderna’s Spikevax receives full FDA approval for use in children at increased risk for COVID-19, expanding protection ahead of the 2025–2026 virus season.
The influenza vaccine may do more than just prevent flu-related deaths
March 1st 2007The influenza vaccine not only reduces the morbidity and mortality of influenza, it also reduces the risk of death in adults hospitalized with community-acquired pneumonia (CAP). Spaude and colleagues found that this protective effect covered in-hospital all-cause mortality, even after adjustment for pneumococcal vaccination status and the presence of comorbidities.
Diffuse alveolar hemorrhage in a patient with SLE
March 1st 2007The authors present a case in which the initial manifestation of systemic lupus erythematosus (SLE) was diffuse alveolar hemorrhage (DAH), which is a rare presentation that carries a high risk of death. The patient failed to respond to standard therapy but was successfully treated with plasmapheresis.
a 1 -Antitrypsin deficiency:An overlooked cause of emphysema
March 1st 2007a 1-Antitrypsin (AAT) deficiency is a genetic disorder that predisposes patients to early-onset emphysema and chronic liver disease. It is more common than is generally appreciated, occurring in about 1 in 2000 to 5000 persons.1,2 It has been estimated that 1% to 2.5% of persons with chronic obstructive pulmonary disease (COPD) in the United States have AAT deficiency.1,2
Herpes Simplex Virus (HSV) Infection
March 1st 2007This infection is caused by reactivationof varicella-zoster virus (VZV),which may remain latent in thedorsal root and cranial nerve gangliafor decades. Reactivation oftenoccurs for no apparent reason, althoughstress and immunosuppressionmay increase the risk.
Young Child With Hematuria and Dysuria
March 1st 2007A 3-year-old girl is brought to the office because of a1-week history of hematuria and dysuria. Her motherhad noticed bright red blood in the child’s urine anddiaper. The child did not have dysuria initially but latercomplained of a burning sensation.
Diabetic Foot Problems: Keys to Effective, Aggressive Prevention
March 1st 2007ABSTRACT: A 4-pronged approach that includes patient education, skin and nail care, appropriate footwear, and proactive surgeries can effectively prevent diabetic foot problems. Teach patients with diabetes to examine their feet daily to detect new onset of redness, swelling, breaks in the integrity of the skin, blisters, calluses, and macerated areas. Have them follow a daily foot care regimen that includes warm water soaks and lubrication, and have them keep toenails properly trimmed. Recommend that patients select shoes that fit properly and have sufficient padding and toe box space; have them use inserts, lifts, orthoses, or braces--as recommended-to correct abnormal gait patterns. Finally, if deformities develop, simple proactive surgical procedures can correct these problems before they result in the development of wounds.
CROI: Maraviroc Has Double Success In Failing HIV Patients
February 28th 2007LOS ANGELES -- An investigational anti-HIV drug called maraviroc, the first CCR5 inhibitor, significantly outperformed placebo in patients who were failing anti-retroviral therapy, according to interim results from two major phase III trials.
One in Four Women Infected with Human Papillomavirus
February 28th 2007ATLANTA -- One in four women in the U.S. ages 14 to 59 are infected with human papillomavirus (HPV), according to the first nationally representative study. Some 3.4% of the women tested positive for the four major strains against which the new HPV vaccine protects, representing an estimated 3.1 million women.
Kids With Asthma Lose Fewer School Days on Leukotriene Antagonist
February 15th 2007MELBOURNE, Australia -- For children with intermittent asthma, a short course of Singulair (montelukast), a leukotriene antagonist, given at the first sign of an episode may reduce acute care visits, reported Australian investigators.