Headache and Migraine

Findings for atogepant from the phase 3 PROGRESS study will form the basis of a submission by AbbVie to FDA for a label expansion in the US.

Lifetime use of opioids for migraine was found to be higher than for triptan medications. Try these 10 questions on other OVERCOME findings.

Findings on use of acute and preventive migraine therapy continue to reveal gaps with far more patients eligible than the proportions using either type.

When choosing a migraine treatment for acute attack relief, the American Headache Society suggests following these steps.

Researchers also found that women with migraine with aura had a higher risk of preeclampsia than those with migraine without aura.

Intranasal CGRP inhibitor zavegepant met coprimary regulatory endpoints in pivotal phase 3 trial in adults with migraine; FDA submission planned for Q1 2022.

Five migraine management essentials for PCPs and headache patients are summarized with the mnemonic SEEDS. 

The daily oral CGRP inhibitor is the only agent in the class developed specifically for prevention vs acute treatment of episodic migraine.

The DHE nasal spray delivered pain relief at 2 hours for 66% of patients; 93% of those remained pain-free at 24 hours and 86% at 2 days post-dose.

Oral CGRP inhibitor atogepant significantly reduced monthly headache days and improved daily function in adults with 4 to 14 headaches per month.

A woman in her 50s who has a history of tension headache presents to the ED with a headache different from any she has had. Mild photophobia is the only finding on physical exam. Your dx?

Early diagnosis of cluster headache, commonly considered the most painful condition on earth, is essential to curbing disability; here's what primary care clinicians need to know. 

Migraine headaches are a condition commonly seen in primary care. Here is a top-line look at the evidence for efficacy of the wide range of treatments available.

In a phase 2/3 study, nearly half of rimegepant-treated patients demonstrated ≥50% reduction in the number of moderate-to-severe migraine days per month

How has the COVID-19 pandemic impacted migraine patients? We asked 3 migraine specialists that question and more.

Incident cardiovascular disease is significantly increased among women with migraine with aura vs migraineurs without aura and those who do not have migraine.

Analysis of data from more than 21 000 migraineurs found that less than 1 in 3 take prescribed acute medications and less than 1 in 5 take prescribed preventive agents.

Two first-in-class migraine drugs, the first generic version of NuvaRing®, and 7 more fourth quarter FDA-approved drugs for primary care.

The FDA has approved the first oral CGRP receptor antagonist in pill form for the acute treatment of migraine with or without aura in adults.

ICYMI: Get a quick look at 12 of the many drugs FDA-approved in 2019 for conditions commonly seen in primary care.

When a patient presents to their primary care physician with a headache, it's not always diagnosed as the migraine it is. These 6 tips from a neurologist can help.

"Typical aura without headache" is a relatively rare headache diagnosis and not easy to make. Three leading headache specialists offer guidance on how to recognize and treat.

Lasmitidan is the first 5-HT1F receptor agonist to receive FDA approval and was found superior to placebo for reduction of migraine pain and most bothersome symptom at 2 hours.

Children, tweens, and adolescents with migraine can use Migraine Trainer to log and share details that will help physicians individualize care in this vulnerable population.

Throbbing occipital headache x2 wks; abrupt onset, no history. Reason for alarm? Neurologist Peter McAllister, MD, suggests you SNOOP first.

What's your caffeine IQ? Test your knowledge on the latest caffeine research from its effect on cardiovascular disease to liver cancer with this brief quiz. 

Injectable medications for migraine are effective, inexpensive, and easy to store. Try these 5 questions on 5 you may want to have on hand.

Read why one migraine specialist believes that biofeedback should be the first line of treatment in patients with migraine. 

A cup of coffee/day keeps migraine away? It can, but before recommending another cup to migraine patients, review findings just published.

Caffeine moderation moderates cardiovascular risk, caffeine is not what is keeping you up at night, and 4 more recent studies on caffeine intake.