Study: Black Women with PCOS Have Greater Cardiometabolic Risk vs White Women
ENDO 2021: A meta-analysis found increased cardiometabolic risk among Black women with PCOS vs White counterparts even though fasting glucose levels were comparable and triglyceride levels lower.
Obese Patients with COVID-19 at Higher Risk for ICU Admission, Longer Stay
ENDO 2021: Patients with severe obesity hospitalized for COVID-19 were twice as likely to require ICU admission vs those with normal BMI, according to new findings.
UPDATE: AstraZenca-Oxford Vaccine 79% Effective in US Phase 3 Interim Analysis
Updated: The vaccine, AZD1222, showed 100% efficacy against severe disease/hospitalization and, notably, 80% efficacy in trial participants aged ≥65 years, the company reports.
Hyperglycemia in Hospitalized COVID-19 Patients Linked with Worse Outcomes
COVID-19 patients with hyperglycemia on hospital admission, with and without diabetes, had increased odds of intubation, ICU admission, and mortality, according to research presented at ENDO 2021.
Novel Once-weekly Insulin as Effective as Once-daily in Type 2 Diabetes with Less Hypoglycemia, Weight Gain
ENDO 2021: An investigational once-weekly insulin formulation was found as effective as daily basal insulin injection for glucose control with lower rates of hypoglycemia and less weight gain.
Semaglutide 2.4 mg Reduces Visceral Adiposity, Improves Lean Body Mass-to-Fat Mass Ratio
ENDO 2021: Obese individuals treated with semaglutide 2.4 mg vs placebo demonstrated improvements in body composition paralleling weight loss that may reduce risk for cardiometabolic disease.
Guideline-directed Osteoporosis Treatment Found in Decline
ENDO 2021: Fewer than 1-in-10 older adults with a hip fracture had been prescribed bone-directed treatment in the 6 months prior to the incident, according to research on trends in treatment.
Asthma Guidelines in Practice: Clinicians Rate their Adherence
How do clinicians who treat asthma rate their own adherence to tenets of evidence-based guidelines? Lead authors on analyses of a national survey respond.
Top 10 States: Percentage of Population Fully Vaccinated
In percentage of population fully vaccinated against COVID-19, Alaska currently leads and Utah brings up the rear. Find out which states are in between.
Expert Interview: The Challenge of Asthma Management in Primary Care
Primary care clinicians provide ~60% of asthma care in the US. The challenge is real and we discussed details with experts Drs Michelle Cloutier and Lara Akinbami.
Anosmia, Other Neurologic Symptoms Seen in Half of COVID-19 Patients at ED Presentation
Study: Anosmia, myalgias, and headache were the most common extrapulmonary symptoms seen in COVID-19 patients at first presentation, say investigators.
ACS Diagnosis Missed in Women More Frequently than in Men, Study Finds
Suspicion for ACS in women was lower than that for men even in the presence of significant risk factors for heart attack, study authors report.
COVID-19 Vaccines: 8 Myths and the Facts to Refute Them
We compiled the top trending Myths about the COVID-19 vaccine in wide circulation and added the Facts to help you educate your patients.
Chronic Diseases in Multimorbidity May Share Origins, Study Finds
Using metabolomic profiling from more than 11 000 individuals, researchers identified common pathways linking seemingly unrelated diseases that often co-occur.
COPD Outcomes Improve with Triple Therapy, Regardless of Exacerbation History
Post-hoc analysis of the phase 3 KRONOS study concluded that the benefits in COPD exacerbation seen were not driven by the small subgroup with a prior history of exacerbations.
The Migraine Research Renaissance and Where it is Headed: A PI Interview
New and highly specific migraine drugs have significantly changed the clinical landscape for patients. We talked with Peter McAllister, MD, about where the research goes next.
CDC Lifts Masking, Distancing Requirements for Fully Vaccinated Individuals
The CDC on March 8, 2021, lifted some COVID-19 restrictions for fully vaccinated Americans, including the need for a mask and social distancing in certain situations.
Patients with PAH-COPD May be at Higher Risk than those with Idiopathic PAH
Transplant-free survival was found lower among patients with pulmonary hypertension-COPD than among those with IPAH in a new study published in CHEST.
Routine Adult Vaccination Rates Still Low: Slow Post-lockdown Rebound
Routine adult vaccination rates have yet to reach pre-pandemic levels, according to a report in MMWR this week. Which vaccines are most affected and which groups are lagging?
ID Expert Talks about the Year that Brought Us the COVID-19 Vaccine
The COVID-19 vaccine development story of 2020 was the focus when infectious disease specialist and AIDS researcher Dr Rodger MacArthur spoke with Patient Care Online in January.
Significant Reductions in Exacerbations Seen in Broad Population of Severe Asthma Patients
Statistically significant reductions in annual exacerbation rates were seen across baseline eosinophil and exhaled FeNO level and allergy status with telepezumab, in the phase 3 NAVIGATOR trial.
Expert-guided Online Decision Tool Supports Real-time Treatment Choice for Severe Asthma
Treatment for severe asthma may be enhanced using an online decision support tool that draws on expert treatment decisions for a wide variety of potential patient scenarios.
Disease Severity of Asthma, COPD May Up Risk for Severe COVID-19
AAAAI Virtual Annual Meeting. Severity of underlying airways disease and not prior use of corticosteroids posed a risk of more severe COVID-19, a new study finds.
Study Finds Dupilumab Effective for Severe Atopic Dermatitis in Real-world Setting
Dupilumab therapy for 4 weeks in adults with severe atopic dermatitis resulted in significant improvements in clinical outcomes with no adverse events reported.
ACIP 2021 Adult Immunization Schedule Changes: A Quick Take
Review changes to the CDC Advisory Committee on Immunization Practices' 2021 recommended vaccination schedule for adults with this short slide-show review.
Asthma Patients with COVID-19 at Comparable Risk of Hospitalization
Patients with COVID-19 who have asthma share a similar risk of hospitalization with patients with the infection who do not have asthma, according to new research.
Top 10 States Ranked by Percentage of COVID-19 Vaccines Given
COVID-19 vaccination progress based on proportion of vaccines administered is currently best in New Mexico and worst in Tennessee. Find out which states are in between.
Use of Face Masks Does Not Affect Oxygen Saturation in Asthma Patients
AAAAI Virtual Annual Meeting. Among patients with asthma, wearing a mask, regardless of type or duration of use, had no significant effect on oxygen saturation.
Biologic Eliminates or Reduces Oral Steroids in Severe Asthma: PONENTE Trial
AAAAI Virtual Annual Meeting. Two-thirds of severe asthma patients dependent upon oral corticosteroids stopped or maximally reduced use, according to the trial data.
How Will Your Patients Reengage with Health Care? 4 Group Profiles to Consider
Post-COVID-19 health care delivery will depend, in part, on patient preference and lingering concerns. New research identifies 4 patient groups with divergent feelings.
