Pericardial Fat Increases Risk for HF, Especially HFpEF
Results of this large study also suggest women with high pericardial fat volume are at greater risk for HF than men, findings that have implications for stratifying prevention and treatment.
5 Myths that Persist about COVID-19 Vaccines
Truth: 67% of US unvaccinated adults believe or cannot judge the veracity of the 5 myths that follow. With more than half the population not fully vaccinated, there is more work to do.
SPRINT Trial Results Confirmed in New Analysis: Yes, Lower is Better
An analysis of final data from the landmark SPRINT trial has confirmed findings that support aggressive treatment of hypertension to reduce CV morbidity and mortality.
Moderna COVID-19 Vaccine Found Safe, 100% Effective in Adolescents Aged 12-17 Years
In the phase 2/3 TeenCOVE study, Moderna's mRNA-1273 demonstrated immunogenicity noninferior to that seen in the phase 3 adult study comparator group.
SARS-CoV-2 Variants: Update on CDC Classifications
The CDC defines SARS-CoV-2 variants as of interest, of concern, and of high consequence. Get a quick update on how knowledge of known variants is changing.
10 States with the Highest Percentage of Fully Vaccinated Population
Maine continues to lead the country in percentage of population fully vaccinated at 51.82%, according to CDC data. Mississippi has shifted into the 51st spot.
SURPASS-4: Tirzepatide Reduces A1c, Weight vs Glargine in Patients with T2D, High CV Risk
New topline data from the global SURPASS-4 trial shows treatment with investigational agent tirzepatide led to superior reductions in A1c and body weight vs insulin glargine.
ACC.21: Finerenone Shows Potential to Delay Afib Onset in Patients with CKD, T2D
ACC.2021: A new analysis of FIDELIO-DKD found patients with chronic kidney disease and type 2 diabetes were about 30% less likely to develop atrial fibrillation vs those treated with placebo.
What do Final-year Medical Residents Want in 2021?
Most 2021 final-year medical residents want to work in hospital settings, none want to work in rural areas, and male residents expect to earn more than $250 000 in their first practice.
VIDEO: Keep NASH on the Tip of your Diagnostic Tongue
VIDEO: Given the increasing morbidity and mortality associated with fatty liver disease in the US, it should be on the "tip of [your] diagnostic tongue," says Seth Baum, MD. He explains why.
ATS.2021: Tezepelumab Significantly Reduced Asthma Exacerbations Requiring Hospitalization in Phase 3 NAVIGATOR Trial
ACC.21: Survival After MI Far Worse for Black Patients from Disadvantaged Neighborhoods
ACC.21: Black patients from disadvantaged neighborhoods were found almost 20% more likely to die within 5 years of MI than white patients from well-resourced ones in a new study.
ATS.2021: Study Finds Odds of Uncontrolled Asthma Increase with Higher Pandemic-related Stress
ATS.2021: Odds of uncontrolled asthma in response to pandemic-related stress increased in a significant dose-response manner among adult respondents to a new survey.
ACC.21: Prediabetes Significantly Increases Risk for MACE, According to New Findings
ACC.21: Findings from a study released in advance of the ACC annual meeting suggest that prediabetes confers nearly twice the risk of major cardiovascular events vs normoglycemia.
AHA Statement on Obesity and CVD: 10 Key Points, to Start
The links between obesity and cardiovascular disease are many, including direct cause and effect. Click through the 10-slide summary of a new AHA statement for a first look.
ATS.2021: At-risk Asthma Phenotypes Defined Using 4 Simple Metrics
ATS.2021. Study authors categorized asthma patients using age at onset, T2 biomarkers, and IL-6 levels, creating 12 phenotypes for additional study.
Black Women at Risk Early in Life for Future Cardiovascular Disease
ACC.21: High rates of obesity, hypertension, and hyperlipidemia found in Black women in their 20s and 30s are of significant concern, says the author of a study to be presented at the ACC meeting.
FDA Expands Pfizer-BioNTech COVID-19 Vaccine EUA for Adolescents Aged 12-15 Years
Agency expansion of the COVID-19 vaccine EUA to include this younger group is an important step toward achieving herd immunity in the US, particularly as vaccine uptake slows across the country.
Sugar-sweetened Drink Consumption May Increase Risk for Early-onset Colorectal Cancer
A new study found that women who consumed ≥2 servings/day of sugar-sweetened beverages had a 2.2-fold higher risk for early onset CRC vs those who had less than 1 serving/week.
T2D Complications Associated with Objective Measure of Poor Medication Adherence
Robust analyses of urine metabolites detects poor adherence with prescribed treatment in T2D and is associated with prevalence of micro- and macrovascular complications.
USPSTF: Vitamin E, Beta-carotene Supplementation Not Recommended for CVD, Cancer Prevention
The USPSTF states that evidence is insufficient to determine benefits and harms of most supplements for prevention of the diseases but warns against vitamin E and beta-carotene.
COVID-19 Vaccine Tipping Points: KFF Data on States at Risk
A number of US states fall below the national average of ~50% adults having received at least 1 dose of COVID-19 vaccine and could be at risk of future virus spread.
Diabetes Management in CKD: 10 Top Takeaways from KDIGO 2020
The 2020 Kidney Disease: Improving Global Outcomes Clinical Practice Guideline integrates new treatments and practices with existing management strategies for CKD patients with diabetes.
ACP: DOAC Dos and Don'ts Primer with Stephan Moll, MD
ACP 2021: Dr Stephan Moll covers the basics of DOAC duration for VTE, use of anticoagulation in special populations, and perioperative use of DOACs
ACP: ASCVD Risk Estimation for Primary Prevention with Donald Lloyd-Jones, MD, ScM
"Risk estimators do not prescribe a drug," says Dr Lloyd-Jones. They are tools to help make the decision to prescribe the drug. He explains how to use them in primary care.
ACP: Clyde Yancy, MD, MSc Reviews Advances in Heart Failure Research and Treatment
ACP: Clyde W Yancy, MD, gave a comprehensive update on a year's worth of pivotal science in treatment of heart failure. Here are the highlights.
Bariatric Surgery Associated with Reduced Mortality in Patient with T2D, Obesity
Authors of a new study say their findings suggest bariatric surgery should be considered first-line treatment for the management of obesity in patients with type 2 diabetes.
CDC: Two-thirds of Patients with Mild COVID-19 Get New Diagnosis within 6 Months
More than two-thirds of a large group of patients not hospitalized for COVID-19 made at least 1 outpatient visit and left with a new diagnosis within 6 months of their first diagnosis.
10 States with the Highest Percentage of Population Fully Vaccinated
Maine currently leads the country in percentage of population fully vaccinated against COVID-19. Wherever you practice primary care, please keep the vaccine conversation going.
A Weight-centric Approach to Obesity with T2D: How Pharmacotherapy Works
For frontline clinicians who care daily for patients with obesity and type 2 diabetes, a weight-centric approach to T2D, including antiobesity drugs, could help improve outcomes.