Prediabetes Affects More than 97 Million Americans but 77 Million of Them Are Not Aware
The mildly elevated glycemia of prediabetes is a pathological condition with serious risks for those 77 million, says endocrinologist Samuel Dagogo-Jack, MD, DSc.
Lilly’s Oral GLP-1 Orforglipron Shows Significant and Competitive A1c and Weight Reductions in Phase 3 Trial
The positive topline data from the phase 3 ACHIEVE-1 trial suggest the small molecule GLP-1 mimetic could compete with blockbuster weekly injectables for reducing weight, A1c.
ACIP Expands RSV Vaccine Recommendation to At‑Risk Adults Aged 50–59 Years
The CDC advisory committee also endorsed GSK's pentavalent meningococcal vaccine.
GSK: 3-Year Efficacy Data for Arexvy in Older Adults Published in Lancet Respiratory Medicine
A single dose of the RSVPreF3 demonstrated a cumulative efficacy of 62.9% against RSV-LRTD across 3 seasons in adults aged 60 years and older.
Bringing Behavioral Health Into Primary Care: A Collaborative Care Roadmap
ACP 2025: Matthew Press, MD, shares actionable steps for primary care physicians to adopt a collaborative care model, including how to start small and partner with other practices.
Anaphylaxis Treatment Often Falls Short in Prehospital Care: Daily Dose
Your daily dose of the clinical news you may have missed.
Which CRC Screening Method for Which Patient? Rachel Issaka, MD, MAS, Calls for an Honest Conversation
Issaka, from the Fred Hutch Cancer Center, said insurance coverage, a patient's resources, and social determinants of health all factor in the choice.
10 Drugs Approved for Primary Care: Q1 2025
Review 10 new FDA-approved drugs that may soon find a place in your prescribing routine, including new treatments for UTIs, acute pain, and more.
A Comprehensive Approach to Obesity Treatment: Combining Lifestyle, Medication, and Surgery
ACP 2025: GLP-1 medications are advancing obesity care, but lifestyle changes and bariatric surgery remain key components. Laura Davisson, MD, discusses how to personalize treatment strategies.
FDA Grants First-in-Class Marketing Authorization for Digital Therapeutic in Episodic Migraine Prevention
CT-132 is a 12-week app-based intervention that uses validated behavioral techniques to modulate labile brain circuitry involved in migraine, according to Click Therapeutics.
Emergency Care for Cannabis Use Associated with Increased Risk for Dementia in Adults: Canadian Population Study
Adults with a cannabis-related acute care visit or hospitalization were at 23% and 72% greater risk of a new dementia diagnosis within 5 years, a new study finds.
New Insights Into Treatment Resistant Depression Show Gaps in Care: Daily Dose
9 Common Myths About Cancer Screening and the Facts for Your Patients Who Believe Them
Myths and fears about cancer screening may be keeping some of your patients from important tests. Always ask about misconceptions, and then offer the facts.
Matthew Press, MD: How Penn Medicine’s CoCM Model Helps PCPs Treat Mental Health—and Avoid Burnout
ACP 2025: Dr Press discusses how the Penn Integrated Care model equips primary care physicians to manage mental health conditions more effectively while reducing burnout.
CRC Screening Outreach Significantly Reduces Black-White Disparities, Including CRC Mortality Gap
ACP 2025: Rachel Issaka, MD, MAS, reviewed data from a Kaiser Permanente program that narrowed racial and ethnic disparities in CRC screening compliance and related deaths.
Oral Gepotidacin Noninferior to Standard Therapy for Gonorrhea in Phase 3 Trial
Data from the EAGLE-1 study found gepotidacin to be noninferior to ceftriaxone plus azithromycin for treating uncomplicated urogenital gonorrhea.
Prepregnancy Obesity, Not Pregnancy Complications, Drives Midlife Cardiovascular Risk in Women, Suggest HAPO FUS Study Findings
Gestational diabetes and hypertensive disorders of pregnancy may be markers for rather than mediators of risk for future CVD, according to new research.
Mediterranean Diet Combined with Physical Activity Mitigate Bone Density Decline in Older, At-Risk Women, New Analysis Finds
Following a Mediterranean-style diet and a prescribed regimen of physical activity was significantly protective of BMD, particularly at the lumbar level, over 3 years.
Study Links CV Mortality Rise to Maternal Health Disparities: Daily Dose
FDA, Novo Nordisk Investigating Counterfeit Semaglutide Injection in US Supply Chain
The FDA and Novo Nordisk are urging health care professionals to check semaglutide (Ozempic) injection 1 mg lot PAR0362 with serials starting 51746517.
