GLP-1s May Cut Obesity-Related Cancer Risk: Daily Dose
Your daily dose of the clinical news you may have missed.
Expanding Access to Atopic Dermatitis Treatments for Children: A Conversation with Elizabeth Swanson, MD
At RAD 2025, pediatric dermatologist Elizabeth Swanson, MD, discussed the value of focused AD education and anticipated label expansions for several treatments.
Q&A: JAK Inhibitor Safety in Context and the Rich Atopic Dermatitis Pipeline, with Leon Kircik, MD
RAD 2025: Renowned AD investigator Kircik provides the history behind the classwide black box warning, highlights JAK inhibitor efficacy, and toplines exciting AD research.
Joint FDA Studies Show DermaSensor Device Reduces Missed Skin Cancers in Primary Care by 50%
FDA-cleared DermaSensor device shows 96% sensitivity and reduces missed skin cancer diagnoses by 50% in primary care, according to new data.
Why the OX-40/OX-40L Pathway Matters in Atopic Dermatitis—and What’s Next: A Q&A with Johann Gudjonsson, MD, PhD
At RAD 2025, Johann Gudjonsson, MD, PhD, discussed the OX-40 pathway’s role in AD, genetic links to disease risk, and promising combination therapies in development.
Cycling Linked to 19% Lower Risk of Dementia in Large UK Biobank Study
Cycling and mixed cycling were associated with a reduced risk of all-cause dementia, including of young onset, as well as increased hippocampal volume.
Guideline Topline: 14 Key Lifestyle Interventions to Treat, Prevent Type 2 Diabetes
These 14 recommendations from the American College of Lifestyle Medicine comprise the core of the first-ever guideline centered on lifestyle change as a first-line intervention.
New Study Highlights Lengthy Journey to Phase Out Low-Value Cancer Screenings in the US
Valid and accessible measures are needed to monitor low-value care practices and set benchmarks for de-implementation efforts, researchers reported.
High Discontinuation Rates of GLP-1 RA-Based Drugs Linked to Weight Loss Far Below Phase 3 Clinical Trials
High discontinuation rates as well as lower maintenance dosages of semaglutide and tirzepatide were among the independent predictors of lower real-world weight loss.
A Close Look at Flexible Dosing Strategies for Atopic Dermatitis in Adults with Raj Chovatiya, MD, PhD, MSCI
RAD 2025: Chovatiya toplines shifts in dosing strategies for topical, oral, and injectable AD therapy observed in both clinical trials and clinical practice.
The Weekly Dose: Cannabis, Contraceptives, and Advances in Alzheimer Disease and Gonorrhea Treatment
Clinical insights on cannabis and dementia, hormonal contraceptives and postpartum depression, the FDA-approved blood test for Alzheimer disease, more.
First-Ever Guideline Establishes Lifestyle Intervention as Central Strategy in Treating, Reversing Type 2 Diabetes and Prediabetes
Novel guidelines include specific strategies that support the prescription, implementation, and monitoring of lifestyle changes to reach glycemic control and, possibly, disease remission.
Pediatric Atopic Dermatitis: Navigating Patient, Provider, Caregiver Connection with Peter Lio, MD
RAD 2025. Peter Lio, MD, shares details from his presentation on shared decision making when treating children with atopic dermatitis.
Novavax Releases Promising Data from Descriptive Trial for COVID/Flu Combination and Stand-Alone Flu Vaccines
Both investigational vaccines induced strong immunity across all antigens and researchers reported no new safety signals, supporting phase 3 development.
Lebrikizumab Demonstrates Efficacy, Safety in Patients With Skin of Color With AD
RAD 2025. Lebrikizumab improved skin clearance, itch, and pigmentation in patients with skin of color and atopic dermatitis, with strong safety data through 24 weeks, according to late-breaking data.
The US Adult Vaccination Gap: New Analysis Quantifies the Divide, Recommends Solutions
Vaccination rates among US adults are roughly half that of pediatric populations, exposing older adults to risk for disease and complications, according to a new analysis.
Flexible Dosing in in Atopic Dermatitis Treatment: Notes on Real-World Use with Raj Chovatiya, MD, PhD, MSCI
RAD 2025: Chovatiya spoke at RAD about the need to better understand how treatments for AD are being used in the real world, after symptoms subside and skin signs clear.
Understanding Chronic Hand Eczema: More Than Just Atopic Dermatitis
RAD 2025: Jiade Yu, MD, discussed chronic hand eczema as a distinct condition from AD, highlighting its clinical burden and emerging treatments, such as delgocitinib.
Arcutis Begins Study of Roflumilast Cream 0.05% in Infants with Atopic Dermatitis
Arcutis Biotherapeutics announced today the enrollment of the first patient in the phase 2 INTEGUMENT-INFANT trial.
George Medicines Announces FDA Approval of Polypill for Treatment of Hypertension in Adults
The novel triple fixed-dose combination of telmisartan, amlodipine and indapamide, is the first of its kind approved for initial treatment of hypertension.