Topline Real-World Data Show Fezolinetant Improves VMS, Sleep, and Work Productivity in Women With Confirmed Menopausal VMS
TMS: New preliminary data show reduction in bothersome VMS as early as week 4, an effect that led to statistically significant improvements across other life domains.
Four Studies Build Evidence for Elinzanetant as a Safe, Effective Nonhormonal Option for Menopausal Vasomotor Symptoms
TMS: New data pooled across clinical trials confirm elinzanetant’s consistent efficacy, safety, and sleep benefits across diverse populations of menopausal women.
Elinzanetant Improves Sleep Through VMS-Independent Mechanisms, According to New Pooled Analysis
TMS: Mediation analysis found that more than half of elinzanetant's sleep benefit occurs independently of nighttime hot flash reduction, challenging VMS-centric models.
Black Women Prescribed Menopausal Hormone Therapy at Significantly Lower Rates Despite More Severe Symptoms, Study Finds
TMS: Black women are up to 36% less likely to receive a prescription for systemic estrogen than White women, despite more acute and persistent VMS, authors said.
Age, Not Menopause Stage, Drives Cortical Volume Reduction in Midlife Women, New Study Suggests
TMS: Findings from a large study presented at TMS 2025 counter previous reports suggesting menopause-specific effects on brain structure at midlife.
Study Finds Atypical MI Causes More Frequent in Women Aged Under 65: Daily Dose
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New Large-Scale Study Challenges Previous Research on Menopause and Brain Structure
New research presented at TMS 2025 suggests menopause stage does not accelerate brain volume loss—age does. Study author discusses clinical implications for PCPs.
Early Natural Menopause Associated With Increased Metabolic Syndrome Risk, According to New Research
TMS 2025: Early natural menopause significantly raises the risk of metabolic syndrome, highlighting the need for proactive health interventions in at-risk women.
Plasma Biomarkers Achieve High Accuracy for Confirmatory Aβ Positivity in Eligibility Test for DMT in Alzheimer Disease
Plasma assays combining p-tau217 and Aβ42/40 accurately confirm AD, supporting patient eligibility for anti-amyloid disease-modifying therapies.
Orforglipron Achieves Up to 12% Weight Loss in Obesity Phase 3 Study: Daily Dose
Oral Semaglutide Wins Approval to Reduce Risk of MACE in Adults with T2D at High Risk
The first FDA-approved oral GLP-1 receptor agonist received an expanded indication for both primary and secondary prevention in T2D patients at elevated CV risk.
FDA Approves TSLP Inhibitor Tezepelumab for Chronic Rhinosinusitis With Nasal Polyps
Tezepelumab's approval marks the first for a TSLP-targeting biologic for CRSwNP, backed by WAYPOINT trial data showing sustained symptom and polyp reduction.
Grail Reports Strong Performance for Galleri Blood Test Ahead of FDA Submission
GRAIL's PATHFINDER 2 study shows Galleri blood test detected 7 times more cancers when added to standard screenings, with 99.6% specificity and low false positives.
Most Parents Support Childhood Vaccines, But Doubt Flu and COVID-19 Shots: Daily Dose
The Adult Immunization Catch-Up Schedule: A Practical Guide for Primary Care
Vaccine-preventable diseases claim up to 50,000 adult lives each year in the US. Click through this compact reminder of recommended catch up shots for your patient panel.
Undertreated Acute Pain Poses Long-Term Risks, But Prescription Opioids Still Do, Too ...
Undertreated acute pain can lead to life-long chronic pain but there are still few effective opioid-sparing options. A new review reinforces the persistent safety issues.
Diagnosing DVT: Clinical Pearls for Challenging Presentations
A family medicine physician shares a case of massive PE presenting as syncope and explains the history questions that prevent missed DVT diagnoses in primary care.
Identifying and Managing Vascular Disease in Primary Care: A Q&A With Family Physician Kabiul Haque, MD
Primary care physicians enhance early detection and management of vascular diseases, emphasizing patient history, screening, and strong relationships for better outcomes.
New Menopause Survey Finds Energy Loss, Poor Sleep, and Seasonal Symptoms Most Disruptive
The survey of more than 19,000 American women found low energy and sleep problems more disruptive than VMS and that Autumn is the most symptomatic season.
Survey Finds Semaglutide Eases Food-Related Intrusive Thoughts, Boosts Mental Health: Daily Dose
