FDA Expands Pfizer-BioNTech COVID-19 Vaccine EUA for Adolescents Aged 12-15 Years
Agency expansion of the COVID-19 vaccine EUA to include this younger group is an important step toward achieving herd immunity in the US, particularly as vaccine uptake slows across the country.
Sugar-sweetened Drink Consumption May Increase Risk for Early-onset Colorectal Cancer
A new study found that women who consumed ≥2 servings/day of sugar-sweetened beverages had a 2.2-fold higher risk for early onset CRC vs those who had less than 1 serving/week.
T2D Complications Associated with Objective Measure of Poor Medication Adherence
Robust analyses of urine metabolites detects poor adherence with prescribed treatment in T2D and is associated with prevalence of micro- and macrovascular complications.
USPSTF: Vitamin E, Beta-carotene Supplementation Not Recommended for CVD, Cancer Prevention
The USPSTF states that evidence is insufficient to determine benefits and harms of most supplements for prevention of the diseases but warns against vitamin E and beta-carotene.
COVID-19 Vaccine Tipping Points: KFF Data on States at Risk
A number of US states fall below the national average of ~50% adults having received at least 1 dose of COVID-19 vaccine and could be at risk of future virus spread.
Diabetes Management in CKD: 10 Top Takeaways from KDIGO 2020
The 2020 Kidney Disease: Improving Global Outcomes Clinical Practice Guideline integrates new treatments and practices with existing management strategies for CKD patients with diabetes.
ACP: DOAC Dos and Don'ts Primer with Stephan Moll, MD
ACP 2021: Dr Stephan Moll covers the basics of DOAC duration for VTE, use of anticoagulation in special populations, and perioperative use of DOACs
ACP: ASCVD Risk Estimation for Primary Prevention with Donald Lloyd-Jones, MD, ScM
"Risk estimators do not prescribe a drug," says Dr Lloyd-Jones. They are tools to help make the decision to prescribe the drug. He explains how to use them in primary care.
ACP: Clyde Yancy, MD, MSc Reviews Advances in Heart Failure Research and Treatment
ACP: Clyde W Yancy, MD, gave a comprehensive update on a year's worth of pivotal science in treatment of heart failure. Here are the highlights.
Bariatric Surgery Associated with Reduced Mortality in Patient with T2D, Obesity
Authors of a new study say their findings suggest bariatric surgery should be considered first-line treatment for the management of obesity in patients with type 2 diabetes.
CDC: Two-thirds of Patients with Mild COVID-19 Get New Diagnosis within 6 Months
More than two-thirds of a large group of patients not hospitalized for COVID-19 made at least 1 outpatient visit and left with a new diagnosis within 6 months of their first diagnosis.
10 States with the Highest Percentage of Population Fully Vaccinated
Maine currently leads the country in percentage of population fully vaccinated against COVID-19. Wherever you practice primary care, please keep the vaccine conversation going.
A Weight-centric Approach to Obesity with T2D: How Pharmacotherapy Works
For frontline clinicians who care daily for patients with obesity and type 2 diabetes, a weight-centric approach to T2D, including antiobesity drugs, could help improve outcomes.
Cannabis Use may be Deadly in Persons with Arrhythmias, Study Suggests
Among more than 2 million Americans admitted to the hospital for cannabis use, those with a cardiac arrhythmia were more than 4 times more likely to die while hospitalized than those without.
These Two Words Could Change Obesity Treatment, says Harold Bays, MD
Long time cardiometabolic investigator Harold Bays, MD, talks about obesity, new drugs to treat the disease, and how the words "be inefficient" could change thinking about treatment.
NIH COVID-19 Treatment Guidelines Update: Colchicine, mAbs, Convalescent Plasma
The April 21st updates include guidance on use of colchicine, when to use combination anti-SARS-CoV-2 monoclonal antibodies, COVID-19 reinfection, and "long COVID."
VA Study Finds Secondary ASCVD Prevention Lacking for Women
Sex disparities in cardiovascular care in the VA system included less therapy with antiplatelet agents and any intensity statin for women with premature ASCVD than men.
Obesity Expert Discusses an Unexpected Metabolic Response to Weight Loss
Citing a study of "The Biggest Loser" participants, obesity expert Dr Silvana Pannain explains why "Eat less, exercise more," often backfires as a sole intervention for persons with obesity.
Aspirin without Indication Added to DOAC Therapy Ups Risk for Bleeding
Study authors warn that ASA added to a medication regimen may be unintentional and call on clinicians to assess patients on DOACs for concomitant ASA and deprescribe.
Keith C. Ferdinand, MD: COVID-19, Obesity, and the African American Community
Keith C Ferdinand, MD, discusses how deeply-rooted social determinants of health have led to the vastly disproportionate impact of COVID-19 on persons of color.
Best & Worst States for Physicians: 2021 Snapshot
Take a look at the 5 states ranking highest and lowest on metrics including wages, competition, state medical board punishment, cost of malpractice insurance, and size of malpractice payout.
Functional Assessment Strengthens Red Meat-Heart Disease Association
Measures of heart function and anatomy were used to assess the effects of red and processed meat on cardiovascular health; findings were reported at ESC Preventive Cardiology 2021.
Impact of Weight Loss on NAFLD: Is there a Dose-Response Relationship?
Weight loss is known to improve markers of fatty liver disease but authors of a recent meta-analysis took their investigation deeper. Scan through the research to the findings.
Study: HDL Anti-inflammatory Capacity Could Improve CVD Risk Assessment
The indicator of vascular protection against atherosclerotic progression was inversely associated with incident CV events, independent of traditional CVD biomarkers and improved Framingham Risk Score prediction.
FDA/CDC Recommend Pause on J&J Vaccine Use After Reports of Blood Clots
Reports of a rare, severe type of blood clot in 6 women in the US led the agencies to halt use of the J&J product, out of an abundance of caution.
SBP Time in Target Range Associated with Decrease in CV Risk, Study Finds
Post-hoc analysis of the SPRINT trial found greater time spent with systolic blood pressure in target range was significantly associated with decreased risk of MACE.
Black Adults Avoid Hypertension, Reduce CVD Risk with Sustained Lifestyle Habits
Jackson Heart Study participants who maintained a healthy BP, BMI, and never smoked were at lower risk for incident CVD, suggesting targets for intervention in high-risk populations.
Long COVID Review Lead Author Highlights Knowns, Unknowns
Long COVID is now a term recognized worldwide. We talked with Ani Nalbandian, MD, lead author of the most comprehensive review-to-date, about what she and her colleagues have learned.
Diabetes in Patients with CAD Independently Associated with Mortality, CV Events
In individuals with chronic coronary disease, the presence of diabetes increased the rate of death by 38% during a 5-year follow-up period in analysis of a worldwide patient registry.
Interview with NIAAA Director on Rise in Alcohol Use During COVID-19
Director of the National Institute on Alcohol Abuse and Alcoholism George F Koob, PhD, talked with Patient Care Online about dangerous alcohol consumption linked to pandemic-related stress.