The Daily Dose: Dueling DOACS
Your daily dose of the clinical news you may have missed.
We Can't Predict a COVID-19 Surge, But We Can Prepare Patients for It: AAFP Board Chair Dr Sterling Ransone, Jr
It is clear that COVID-19 comes in waves, but it's too soon in the life of the virus to predict patterns, Ransone says. Strategy? Get shots in arms.
Oral Superabsorbent Hydrogel May Help Prevent Progression of Prediabetes to Type 2 Diabetes: New Research
CMHC 2022. Post-hoc analysis of the LIGHT-UP study found GS200 significantly reduced postprandial insulin secretion in adults with overweight and prediabetes.
PCPs, Cardiologists May Not Adequately Stratify, Treat CV Risk in Patients with Type 2 Diabetes
CMHC. PCPs and cardiologists appeared to perform only half of items considered necessary for care of T2D patients in a new simulated patient study.
Apixaban Found More Effective than Rivaroxaban in Patients with AFib and Valvular Heart Disease
In the absence of randomized controlled head-to-head trials comparing the 2 anticoagulants, study authors say clinicians should consider their findings when choosing treatment.
How to Talk to Patients about Coadministration of Influenza and COVID-19 Vaccines This Year
AAFP Board Chair Sterling Ransone, Jr, MD, encourages patients to get both shots at one visit; if they don't, he has strategies to bring them back for the one they didn't get.
AAFP Tips on Getting Shots into Arms this Flu Season with Sterling Ransone, Jr, MD
AAFP Board Chair Sterling Ransone, Jr, MD, offers an Academy refresher on the annual push-back from patients that is so familiar to family medicine clinicians.
Tezepelumab Reduced Exacerbations in Severe, Uncontrolled Asthma, Regardless of Number of Additional Controller Medications
CHEST 2022. Tezepelumab significantly reduced AAER and improved lung function in patients taking 1, 2, or ≥3 long-acting β-agonists in addition to ICS.
Will This be the Year of the Twindemic? AAFP Board Chair Ransone Thinks Out Loud with Patient Care
About half of American adults plan not to get a flu shot this year; everyone is tired of COVID talk and prevention; but flu is brewing in the southern hemisphere, Ransone says.
Early Diabetes Diagnosis in Women Associated with Early Age at Menopause in Large Canadian Cohort
Early age at either type 1 or type 2 diabetes diagnosis was associated with earlier age a menopause, suggesting an impact of diabetes on reproductive health, authors say.
AAFP Board Chair Sterling Ransone, Jr, MD, Has Concerns About Flu Season 2022-2023
Ransone hasn't had a case of influenza in his practice in 2 years, but with mitigation measures all but over and COVID-19 in the wings, this year could be different.
GSK Announces Positive Pivotal Phase 3 Data for Adult RSV Vaccine Candidate
The investigational respiratory syncytial virus vaccine had an overall efficacy of 82.6% against RSV-LRTD, 94.6% against severe disease, and 94.1% in adults with comorbidities.
CVD Risk Factors May Pose Greater Risk for COVID-19 Mortality than Preexisting Heart Disease
Smoking, age, diabetes, race/ethnicity, and BMI may all pose a greater risk for mortality in severe COVID-19 infection than preexisting CVD, study suggests.
FDA Expands EUA for Bivalent COVID-19 Vaccines to Include Children as Young as Age 5 Years
The FDA amended EUAs for omicron-adapted vaccines from both Pfizer and Moderna, authorizing the shots for children and adolescents.
Weight Loss is Essential to Optimize Type 2 Diabetes Treatment Management
Weight loss of at least 5% to 10% for persons with T2D is realistic and essential, says Nisa Maruthur, MD, MHS, coauthor of the new ADA/EASD consensus report.
Americans Have not Been Truthful about Following COVID-19 Precautions
More than 4 in 10 US adults have either misrepresented their COVID-19 status or failed to adhere to public health measures. A new survey found out why.
ADA/EASD Consensus Report on T2D Management: Coauthor Talks Take-homes for Primary Care
Nisa Maruthur, MD, MHS, a primary care physician and consensus report coauthor, discusses elements of the most effective care for patients with type 2 diabetes (T2D).
Simple Primary Care Screening Tool Predicts Asthma Diagnosis in Preschoolers
The noninvasive, easily administered tool was able to predict at age 3 years children who would be diagnosed with asthma at age 5 years.
Clinical Practice Guidelines Could be More Primary Care-friendly, says Nisa Maruthur, MD, MHS
Dr Maruthur, a PCP and coauthor for the new ADA/EASD consensus report on T2D, says that's why this report includes the "tips on implementation" sections.
ADA/EASD Calls for Wide Systemic Change to Address Impact of Social Determinants of Health
As long as the role of social determinants of health in T2D is not prioritized, care for these patients will remain poor and outcomes will not improve, says consensus report author.
SGLT-2 Inhibitors, GLP-1 Receptor Agonists not Cost-effective as First-Line T2D Therapy
When modeled as first-line therapy vs metformin, treatment benefit was significantly outweighed by cost for both classes.
Primary Care Would Benefit from Education on Use of SGLT-2 Inhibitors, GLP-1 Mimetics: Nisa Maruthur, MD, MHS
Dr Maruthur, a primary care physician, helped develop the new ADA/EASD consensus report on T2D management and has suggestions.
Younger Age at Type 2 Diabetes Diagnosis in Adults Increases Risk for Poor Outcomes
A T2D diagnosis in adults aged 50 to 59 years vs 60 to 69 years or ≥70 years was linked to significantly increased risk for cardio- and cerebrovascular disease and all-cause mortality.
ADA, EASD 2022 Consensus Report from the Primary Care Point of View, with Nisa Maruthur, MD, MHS
Dr Maruthur, of Johns Hopkins Medicine, talks about how the concept of "holistic" patient care continues to expand in the management of persons with T2D.
Current Telehealth Use 88% More Likely by Patients with Chronic Conditions: Survey
Telehealth continues to support continuity of care and to increase access to and willingness to use the health care system, according to survey authors.
Antivirals Recommended for Influenza Treatment & Chemoprophylaxis: Basics, Notes, Cautions
This influenza antiviral brush-up slide show reminds you of key features of the 4 FDA-recommended medications, at-a-glance.
FDA Recall Announced for Atenolol, Clopidogrel based on Labeling Mix-up
Only 1 lot of each medication was affected by the mislabeling, according to generic repackaging and distribution services company Golden State Medical Supply.
Early Natural Menopause is a Risk Factor for Lung Disease, Mortality in Women who Smoke
After early natural (vs surgical) menopause, women who continued to smoke had 4.5-fold greater risk of lung cancer and related mortality, report study authors.
Dementia Risk May be Driven by Multimorbidity vs Single Risk Factors, Suggests a New Study
Multimorbidity was associated with a 63% increased risk for dementia among adults older than age 60 years followed for up to 15 years.
Causes of Secondary Hypertension: A Guideline Topline for Primary Care
Obstructive sleep apnea is a cause of secondary hypertension in up to 50% of cases; more common causes here, from the 2017 ACC/AHA hypertension guidelines.
