Noise Pollution and MI: New Jersey Study Finds a Significant Association
ACC 2022. Approximately 5% of hospitalizations for acute MI in the state were found attributable to elevated levels of traffic noise.
Benefits of Exercise in CVD Risk Reduction More than Double in Anxiety, Depression
ACC 2022. Exercise lowers CVD risk in part by reducing the same neurobiologic activity associated with depression and anxiety, according to study authors.
Wearables for Cardio Monitoring May Yield Inaccurate Data Based on Skin Tone
ACC 2022. A new systematic review suggests skin melanin content may impede accurate recording of heart rate and rhythm by wearable devices.
Medication for Opioid Use Disorder Not Prescribed for Majority of Americans in Need
A new study of more than 2 million US adults and adolescents who could benefit from medication for OUD reveals only 1 in 4 reported past-year use.
Migraine Medicine Transformed: Christopher Gottschalk, MD Discusses How We Got to CGRP Inhibition
Gottschalk says CGRP inhibitors have made "...a life-changing transformation in how we think about and the kind of expectations we set for migraine treatment."
FDA Label Expansion Further Simplifies HIV Treatment with Cabotegravir/Rilpivirine
Persons with HIV now have the option to forego initiation of the long-acting injectable with oral formulations of the medications, according to a statement from Viiv Healthcare.
Before Migraine Was a Disease: Headache Expert Christopher Gottschalk, MD, Remembers his Roots
Christopher Gottschalk, MD, a leader in migraine research and clinical care, talks about what drew him to headache medicine early on and what it used to be like.
Early Aspirin Use May Reduce Odds of In-hospital Death in COVID-19 Infection
In a cohort of more than 110 000 patients hospitalized with moderate disease, aspirin use on day 1 reduced odds of mortality by 15% and of PE by 29%.
FDA Issues Safety Alert after Reports of Injury Related to COVID-19 Home Test Kits
Injuries have included accidental use of test solution as eyedrops and children ingesting test parts and swallowing test solution.
Bodyweight Variability May Increase Risk for Major CV Events in Type 2 Diabetes Patients: New Study
Persons with type 2 diabetes who either gained or lost 5% of baseline bodyweight were found to be at higher risk for heart failure, MI, and all-cause death.
Factors Linked to Switching Biologic Treatments in Patients with Severe Asthma
Higher blood eosinophils, younger age, and eosinophilic chronic rhinosinusitis were among factors associated with a switch from initial biologic therapy in a new study.
America's Place in Primary Care: US Ranks Low Among Wealthy Nations
"Exhibit 1. US adults are among the least likely to have a regular doctor or place to go for care." More findings from a Commonwealth Fund report follow.
Empagliflozin CKD Phase 3 Trial Stopped Early for Positive Efficacy Seen in Interim Assessment
The phase 3 EMPA-KIDNEY clinical trial had just met prespecified criteria for positive efficacy when the study's Independent Data Monitoring Committee recommended the early halt.
Meta-Analysis: Current Evidence on Statin Impact on LDL-C and CVD Risk Reduction is Flawed
A new meta-analysis questions the science demonstrating the link between statin-induced LDL-C lowering and improved CV, all-cause outcomes.
Telehealth Secures Foothold but Virtual Care Needs Work, Survey Finds
COVID-19 accelerated telehealth as a standard option but what services will it be best suited for now? A new survey suggests the future.
Potential IBS-Migraine Association Seen in Nationwide Survey
Individuals with migraine were found more likely to have IBS and IBS was more prevalent in those with migraine; both associations were statistically significant.
Apixaban May Be More Effective vs Warfarin in Patients with VTE Who Need Extended Anticoagulation
The direct oral anticoagulant was associated with a lower rate of rehospitalization for VTE among patients extending anticoagulation beyond 90 days, investigators report.
Even Modest Alcohol Consumption Found Linked to Decreases in Brain Volume
Increasing alcohol intake from 1 to 2 drinks per day was associated with brain changes equivalent to aging 2 years, according to a study of more than 36 000.
Atogepant: Pivotal Phase 3 Study Meets Primary Endpoint for Preventive Treatment of Chronic Migraine
Findings for atogepant from the phase 3 PROGRESS study will form the basis of a submission by AbbVie to FDA for a label expansion in the US.
Migraine Management Pearls for Primary Care with Neurologist Jessica Ailani, MD
Consider migraine screening for all women aged 20 to 50 years, suggests Ailani; you'll likely find a majority of them have migraine. More pearls follow.
Migraine-specific Preventive Therapies Can Be a Primary Care Tool, Leading Investigator Says
Migraine-specific preventive therapies should be in the primary care toolbox, according to headache specialist Jessica Ailani, MD.
Migraine Perspectives with Jessica Ailani, MD: Start Migraine Care in Primary Care
Migraine headache specialist and researcher Jessica Ailani, MD, fully supports primary care as the setting for the majority of the treatment for the disease.
Routine Point-of-Care Screening for Afib in Primary Care May Be Most Useful in Oldest Adults
Routine point-of-care AF screening in primary care using a handheld ECG device proved feasible but increased diagnoses only in patients aged ≥85 years, in the VITAL-AF study.
CDC: Uptake in Flu Vaccination is Down in Groups at High Risk for Complications
Drops in flu vaccine coverage this season have been recorded among young children and pregnant people and racial/ethnic gaps in uptake continue, says CDC.
Tezepelumab Significantly Reduced Exacerbations in Patients with Severe Asthma, Respiratory Comorbidities
Tara Carr, MD, led a post hoc analysis of the NAVIGATOR phase 3 trial and presented data on tezepelumab efficacy in the vulnerable subgroup at the AAAAI 2022 meeting.
Unmet Needs in US Migraine Headache Management: OVERCOME Study First Data
Findings on use of acute and preventive migraine therapy continue to reveal gaps with far more patients eligible than the proportions using either type.
CGM-measured Glucose Variability Associated with Diabetes Micro- and Macrovascular Complications
Glycemic variability and low time in range were associated with retinopathy, nephropathy, neuropathy, and CVD in a cohort of more than 20 000 persons, most with T2D.
Acute Migraine Treatment: A Guide to Medication Options
When choosing a migraine treatment for acute attack relief, the American Headache Society suggests following these steps.
Novel Agent for Severe Asthma Halves Exacerbation Rates Across Respiratory Comorbidities
Tezepelumab, a TSLP inhibitor, reduced asthma exacerbation rates in patients with severe uncontrolled disease across a range of respiratory comorbidities.
Asthma May be Linked to Severe COVID-19 but Not to Risk for Hospitalization
Patients with asthma who did require hospitalization for SARS-CoV-2 infection were at greater risk for intubation and remdesivir treatment, a new study reports.
