Panelist discusses how patient cases demonstrate the importance of considering non-steroidal agents in patients of color (due to hypopigmentation risks) and elderly patients (due to skin thinning), concluding that effective atopic dermatitis management requires proper moisturizing, appropriate corticosteroid cycling, and proactive twice-weekly maintenance with newer non-steroidal topicals to prevent long-term complications.
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Clinical case presentations illustrate important treatment considerations in diverse patient populations with atopic dermatitis. A six-year-old patient with skin type VI demonstrated concerning hypopigmentation in antecubital areas despite absent active eczema, highlighting how both the inflammatory process and repeated corticosteroid use can cause pigmentary changes. This case emphasizes the importance of early transition to non-steroidal agents, particularly in patients of color who face higher risks of corticosteroid-induced skin bleaching.
An elderly patient case revealed significant complications from prolonged high-potency topical corticosteroid use, including paper-thin skin, purpura, and increased fragility due to age-related changes and sun damage. These presentations underscore the critical need for appropriate corticosteroid duration limits and early integration of non-steroidal alternatives to prevent irreversible skin changes, particularly in vulnerable populations with compromised skin integrity.
Essential clinical pearls for optimal atopic dermatitis management include recognizing consequences of inadequate treatment—both atopic and non-atopic comorbidities develop when disease control remains suboptimal. Most patients present with mild-to-moderate disease affecting limited body surface area, making them ideal candidates for topical management in primary care settings. Success requires fundamental skincare education, appropriate corticosteroid cycling (1-2 weeks during flares, then non-steroidal maintenance), and utilization of newer non-steroidal agents that offer superior efficacy, tolerability, and simplified treatment regimens for sustained disease control.
Lebrikizumab Demonstrates Efficacy, Safety in Patients With Skin of Color With AD
June 11th 2025RAD 2025. Lebrikizumab improved skin clearance, itch, and pigmentation in patients with skin of color and atopic dermatitis, with strong safety data through 24 weeks, according to late-breaking data.