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An Elderly Man with Worsening Chest Pressure
Patient describes worsening chest pain for 2 years; also easy bruising, bleeding. Follow ED exam on video. What's your diagnosis?
An 87-y/o man is seen in the ED for severe acute chest pain. PMH: 2y of intermittent worsening chest pain at rest; PAD w/ femoral artery bypass; aortic stenosis; no known coronary disease. Easy bleeding; recent derm procedure paused for heavy bleeding. Awake, alert; no pain. Vital signs, WNL; normal ECG.
What's your diagnosis?
Roche, Alnylam Advance Zilebesiran Into Phase 3 CV Outcomes Trial for Resistant Hypertension
September 9th 2025Zilebesiran’s twice-yearly dosing and sustained BP reductions could offer a new therapeutic approach for adults with resistant hypertension and high CV risk who are uncontrolled on current SOC regimens.
Oral PCSK9 Inhibitor Enlicitide Meets All End Points in Phase 3 Hypercholesterolemia Trial
September 2nd 2025At week 24, patients receiving once-daily enlicitide demonstrated statistically significant and clinically meaningful reductions in low-density lipoprotein cholesterol compared with placebo.
