Nirsevimab 90% Effective Against RSV Hospitalization among Infants, According to New CDC Data
Findings support current CDC recommendations that all infants should be protected by maternal RSV vaccination or infant receipt of nirsevimab.
Semaglutide Lowers CKD-Related Events in Persons with T2D, CKD: Daily Dose
Your daily dose of the clinical news you may have missed.
Melatonin Implicated in 11K ED Visits for Infants, Children Over 4 Years: MMWR
Melatonin products, particularly flavored gummies and tablets, were documented in 7 out of 10 ED visits for unsupervised medication exposure in children aged ≤5 years.
Semaglutide 2.4 mg (Wegovy) Wins Expanded Indication to Include Reduced Risk of MACE
The label expansion for semaglutide, based on the SELECT trial, includes data showing reduced risk of CV death of 15% and of death from any cause of 19%.
New Data Show High Prevalence of Dyslipidemia in American Indian Youth
Few participants with dyslipidemia received lipid-lowering medications despite high prevalence, reported authors of the Strong Family Heart Study.
Underrepresentation of Individuals with CKD in CV Medication Trials Found Persistent Over 2 Decades
Authors: Exclusion of people with CKD from CV medication trials has left significant gaps in understanding the effectiveness of these drugs in a highly vulnerable population.
Weak in the Legs and Lips: Seen in the ED
A man in his eighties presents to the ED after 1 week of persistent bilateral leg weakness and dysgeusia that has not worsened. What's your Dx?
Migraine, Persistent VMS Tied to Higher Risk of CVD, Stroke: Daily Dose
Lilly Investigational Alzheimer Agent Donanemab Phase 3 Findings Under FDA Review
The surprise request for review of the phase 3 TRAILBLAZER-ALZ-2 clinical trial findings will delay the original PDUFA timing beyond first quarter 2024.
Initiating Opioid Therapy for Chronic Pain: Does Which Medication Matter?
A new study compared opioid utilization trajectories of patients initiating tramadol, hydrocodone, and oxycodone. Key takeaways at-a-glance, here.
Plastic Debris Detected in Carotid Plaque Linked to Higher Risk for MI, Stroke, Death
Patients who had microplastics and nanoplastics in their carotid plaque were at more than a fourfold risk for MI, stroke, or death compared to those who did not, according to a new study.
Boehringer Ingelheim Will Cap Out of Pocket Costs for Inhalers at $35 per Month
The monthly out of pocket cap applies to all BI inhalers and goes into effect on June 1, 2024.
Neffy May be Safe, Effective for Treatment of Urticaria Flares: Daily Dose
Novo Nordisk Shares Early Findings for Novel Oral Antiobesity Agent
The novel unimolecular pill amycretin combines a GLP-1 and an amylin agonist and led to weight loss of 13% at 12 weeks in a phase 1 trial that just concluded, the company said.
In Pregnant Women with T1D, Greater Time in Range Reduces Adverse Maternal, Neonatal Outcomes
Higher time in optimal glycemic range was associated with reduced risk for preeclampsia and for birth weight larger than gestational age, new research found.
Real-World Studies Show Significant HbA1c Reductions with GLP-1 RA and Freestyle Libre CGM Used Together
One study showed a significant 1.5% decrease in HbA1c 6 months after participants taking a GLP-1 RA started using the Freestyle Libre system.
Semaglutide Shows Potential for Significant CVD Prevention: Daily Dose
FDA Clears First-Ever OTC Glucose Sensor: Dexcom Stelo Glucose Biosensor System
The Dexcom system is for adults over the age of 18 years who do not use insulin, such as individuals with T2D who use oral medications, a US population of 25 million.
Two Biosimilars to Denosumab Win FDA Approval as Amgen and Sandoz Go to Court
Biosimilars Wyost and Jubobonti were approved as interchangeable for Xgeva and Prolia but launch will depend on the outcome of litigation between reference product manufacturers.
CDC: Persons with COVID-19, Flu, RSV, Other Respiratory Viruses No Longer Have to Isolate for 5 Days
The updated guidelines reflect the progress made in protecting against severe illness from COVID-19, said CDC Director Mandy Cohen, MD, MPH.
