FDA Label Update Positions Inclisiran as First-Line Monotherapy for Hypercholesterolemia
Inclisiran can now be used without a background statin, as an adjunct to changes in diet and physical activity for reduction of LDL-C in hypercholesterolemia.
Lecanemab Shows Sustained Benefit at 4 Years in Early Alzheimer Disease: AAIC 2025
Four-year data show lecanemab slows clinical decline in early Alzheimer disease and maintains a consistent safety profile.
Tirzepatide Proves Noninferiority With Dulaglutide for MACE in Lilly's Landmark Incretin Face-Off
In the SURPASS-CVOT trial, tirzepatide reduced MACE-3 by 8% and all-cause mortality by 16% compared with dulaglutide, while also reducing HbA1c and weight.
Nonmedical Exemptions for Vaccines for Children Should be Eliminated: American Academy of Pediatrics
The AAP acknowledges challenges for families but emphasizes mandatory vaccination as crucial for safe school environments.
New Option for Chronic Hand Eczema Gets FDA Green Light: Daily Dose
Your daily dose of the clinical news you may have missed.
New Data Highlight Significant Challenges to Managing CAH: Daily Dose
Amesh Adalja, MD, on How to Defuse Vaccine Safety Concerns Without Derailing the Visit
Dr Adalja offers evidence-based strategies to address patient concerns about aluminum and thimerosal in vaccines.
Maternal Depression Found to Disrupt Emotional Responsiveness, Infant Care: Daily Dose
Amesh Adalja, MD, Breaks Down 2025 Vaccine Policy Shifts for Primary Care
Infectious disease expert Amesh Adalja, MD, outlines the biggest vaccine policy shifts of 2025, including changes to COVID-19 and flu vaccine recommendations.
Donanemab Showed Sustained Cognitive Benefit Over 3 Years in Early Alzheimer Disease
Three-year follow-up data from the TRAILBLAZER-ALZ 2 extension trial supported early initiation and limited-duration dosing.
No Link Found Between Aluminum in Routine Vaccines and Childhood Disorders: Daily Dose
Why 4 Medical Societies Issued a Joint Advisory on Nutrition and GLP-1 Therapy for Obesity
Coauthor of a recent joint advisory, Jonathan Bonnet, MD, MPH, explains how it emerged in response to the growing use of GLP-1 medications for obesity treatment.
Remote Cognitive Screening Platform Expands Access to Early Detection
Linus Health is expanding its AI-powered remote cognitive assessment platform, Anywhere, to expand access to early detection of cognitive impairment.
Solriamfetol Treatment Yields Cognitive Gains in Obstructive Sleep Apnea: Daily Dose
Trontinemab Phase 3 Alzheimer Trials to Launch Following Promising Amyloid Clearance Data
Data from Roche presented at AAIC 2025 highlight rapid amyloid clearance with investigational antibody and potential of pTau217 as blood-based rule-in and rule-out test.
Low-Value Cancer Screenings Persist Despite Guidelines: Daily Dose
The Obesity–Cardiometabolic Link: Root Causes, Screening, and Primary Care's Role
Obesity medicine specialist Monu Khanna, MD, discusses the critical role of primary care in obesity-related risk reduction through lifestyle, behavior, and emerging therapies.
In Screening for Dementia, Time Can Tell A Lot: A Conversation with Researcher David Libon, PhD
In this short conversation, Libon underscores how time-based measures during assessment can reflect subtle neurocognitive changes, augmenting traditional screening.
FDA Extends Review Period for Elinzanetant NDA for Menopausal Vasomotor Symptoms
Bayer's elinzanetant, a potential nonhormonal treatment for menopausal symptoms, awaits FDA approval after a 90-day review extension.
Nirsevimab Highly Effective in Preventing RSV-Related LRTD in Healthy Term Infants, Real-World Study Finds
Nirsevimab lowered the risk of RSV-related illness by over 87% and hospitalizations by 98% in a new study.
.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 "Amesh Adalja, MD, on How to Defuse Vaccine Safety Concerns Without Derailing the Visit")
.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 "Why 4 Medical Societies Issued a Joint Advisory on Nutrition and GLP-1 Therapy for Obesity")
