Bempedoic Acid Meets Primary Endpoint in Key Cardiovascular Outcomes Trial: CLEAR
Approved in 2020 as Nexletol, bempedoic acid as the first ATP citrate lyase inhibitor and oral non-statin therapy to meet the MACE-4 primary endpoint.
FDA Grants Priority Review to sNDA for OTC Intranasal Naloxone HCl
The Agency's priority review of the prescription-OTC switch underscores the urgent need for broader access to the opioid overdose reversal agent.
Drug Overdose Deaths Reach Record High among Pregnant, Postpartum Women in US
Drug overdose deaths increased approximately 81% among pregnant and postpartum women in the US from 2017 to 2020, according to new research.
Butryate Supplementation May Support Pediatric Obesity Treatment
Findings from a new study suggest that supplementing standard care for obesity with butyrate helped reduce BMI, improve glucose metabolism, and reduce inflammation markers.
Daily Dose: Statin Prescribing in Primary Care
Your daily dose of clinical news you may have missed.
Influenza Update: Hospital Admissions Double During post-Thanksgiving Week
The inpatient flu census doubled after Thanksgiving travel and gatherings and ICU beds are full. More at-a-glance stats on Flu in the USA, here.
Daily Dose: Morning Exercise Reduces Risk for Cardiovascular Disease
Pfizer-BioNTech Seek EUA for Omicron Booster in Children Aged Under 5 Years
Pfizer and BioNTech submitted an application to the FDA for emergency use authorization of their omicron BA.4/BA.5-adapted bivalent COVID-19 vaccines in children aged 6 months to 4 years.
Tripledemic Virus Spread Could Jeopardize Holiday Season 2022, says CDC Director Walensky
Flu rates are up after the Thanksgiving holiday week, COVID-19 hospitalizations are increasing, and RSV may or may not be on the wane as Christmas approaches.
Statin Prescribing in Primary Care Boosted with EHR Prompts Plus Patient Alerts
An EHR prompt to a physician alone or in combination with a previsit patient prompt both increased statin prescribing in primary care but a patient prompt alone did not.
Daily Dose: Top Factors that Predict Long COVID
Morning Exercise Reduces Risk for Cardiovascular Disease in a New Study of UK Adults
Being most physically active in the late morning had a 16% decreased risk of coronary artery disease and a 17% decreased risk of stroke compared to midday.
Daily Dose: ASCVD Risk Reduced by 10% with Diet
Diabetes and Obesity: Why Obesity Treatment Should Come First
An obesity specialist explains why clinicians should start at the root cause when managing patients with type 2 diabetes and obesity.
Increased Risk of Long COVID Observed in Women, Persons with Elevated BMI
Analysis of an online survey in the UK found women vs men and higher vs lower BMI were associated with greater likelihood of developing long COVID.
Adults with and Without COVID-19 Report Similar Negative Effects on Wellbeing 3 Months After Illness
Pandemic-related stress and depression may be slowing recovery from long COVID-19 and other illnesses, according to researchers.
Daily Dose: Benzodiazepines for Sleep Disorders Linked to Increased Risk for Drug Overdose among Youth
First Live Microbiota Treatment for Recurrent CDI Wins FDA Approval
The single-dose biotherapeutic remained effective through 6 months for more than 90% of phased 3 clinical trial participants, according to Ferring Pharmaceuticals.
Brush up on RSV: Symptoms, Risks, and Treatment
Respiratory syncytial virus is an age-old winter foe that could affect many of your patients this year. Take a minute and scan these facts for a refresher.
ASCVD Risk Reduced by 10% with Diet, Greater Drops Seen in Women, Black Adults
The therapeutic impact of the dietary lifestyle intervention and the differential effects could have major implications for clinical care and policy, say study authors.
