December 16th 2025
Your daily dose of the clinical news you may have missed.
December 10th 2025
Episode highlights include a new AD blood test for PCPs, sleep effects of elinzanetant among postmenopausal women, lung cancer screening gains, and more.
December 9th 2025
Ob/gyn Dorr outlines how short clinical visits and symptom overlap cause many women to receive an antidepressant Rx instead of perimenopause care.
December 3rd 2025
November 21st 2025
Dorr says symptoms can begin 10 years before cylces cease and explains why the hormonal feast and famine of perimenopause can go unrecognized.
FDA Advisory Panel Calls for Revised Class Labeling for Menopausal Hormone Replacement Therapy
Experts reviewed data from the 2002 Women's Health Initiative study that prompted class warnings for estrogen-containing therapies and called for changes, education.
Pre- and Post-Menopausal Hormone Therapy Has Differential Effect on Breast Cancer Subtypes
Combined estrogen-progestin hormone therapy used to manage VMS of menopause was associated with a higher risk of developing luminal-like breast cancer subtypes and other subtypes.
Machine Learning Predicts Subjective Cognitive Decline During Menopause: Novel Framework for Early Detection
Key predictors of the severity of self-reported cognitive complaints among nurses going through menopause included symptom severity and climacteric stage.
Elinzanetant Gets UK Nod for Moderate to Severe Vasomotor Symptoms in Menopause: Is the US Far Behind?
Bayer's elinzanetant gains UK approval as the first dual-action, nonhormonal treatment for menopausal symptoms.
Social Determinants of Health Affect Use of HRT During Menopause, Study Suggests
Social determinants including partner status, smoking history, and BMI were significantly associated with reduced access to effective hormone therapy for menopausal women.
OASIS-4 Trial: Elinzanetant Reduces Frequency of Vasomotor Symptoms Related to Endocrine Therapy for HR-Positive Breast Cancer
ASCO 2025. Elinzanetant significantly reduced the frequency of VMS vs placebo in women on endocrine therapy for treatment or prevention of HR+ breast cancer.
ACOG 2025: Poster Highlights for Primary Care
Details on 12 key abstracts with clinical relevance for primary care, from menopause management to PPD screening and HPV testing.
Elinzanetant Demonstrates Clinically Meaningful Reductions in Menopausal Vasomotor Symptoms, Meta-analysis Shows
Elinzanetant reduced VMS frequency and intensity, and improved sleep and quality of life, according to the meta-analysis to be presented at the ACOG 2025 meeting.
ACOG 2025 Refresh: Menopausal VMS Education in Primary Care
Building trust with patients early on will help them feel comfortable discussing their symptoms and treatment preferences, says JoAnn Pinkerton, MD.
ACOG 2025: Menopause and Vasomotor Symptoms Preview
A preview of sessions covering menopause and vasomotor symptoms during ACOG 2025 in Minneapolis, MN.
Early Menopause Was Associated with Increased Risk of Cognitive Decline, Depression within 2 Years
The findings suggest that women who experience early menopause (age <40 vs >50 years) may constitute a sex-specific high-risk group for cognitive decline.
Elinzanetant Reduces Vasomotor Symptoms of Menopause Across BMI, Smoking Status
Pooled data from the OASIS clinical trial program showed consistent efficacy of elinzanetant across BMI and smoking history subgroups, highlighting its broad applicability.
MENO! App, a Prescription Digital Therapeutic for Menopause, Validated in New Study
The menopausal symptom and lifestyle management app provides guideline-based CBT principles to augment hormone therapy or even to replace it for some women.
Premature Menopause May Increase Risk of Type 2 Diabetes Suggests Study of 1.1 Million Women
Premature menopause, authors said, should be included in diabetes management guidelines as a risk factor to support screening and prevention.
Menopausal Vasomotor Symptoms: Clinician and Patients Both Need Education, Expert Says
Less than 15% of women in menopause receive treatment for VMS, suggesting a need a for more education and awareness, according to JoAnn Pinkerton, MD.
Menopausal VMS Education in Primary Care: Build Trust First, Says One Clinician