Inflammatory Bowel Disease

The INTERCEPT project aims to build a blood risk score that can identify individuals with a high risk of developing Crohn disease within 5 years of initial evaluation.

Marketed as Omvoh, the therapy is already approved as a first-in-class treatment for moderately to severely active ulcerative colitis.

Find details on US colorectal cancer screening rates, dietary interventions for people with IBS, and research on the primary drivers of cost of IBD care.

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Results from secondary analysis suggest future work is needed to extend the prevention intervention to address additional chronic conditions and substance use.

Unplanned emergency service and medication utilization make up the majority of costs of IBD care, reported researchers.

When does management of Crohn disease warrant assessment of C-reactive protein and fecal calprotectin and when is endoscopy indicated? Test your IBD IQ.

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Findings showed that IBD phenotype varied by race, although foreign-born participants of all races showed evidence of later onset and milder disease.

Nearly half of patients who undergo ileal pouch-anal anastomosis develop pouchitis within 2 years post-surgery; up to 80% will develop it eventually.

The analysis of nearly 300 000 individuals found those with IBD were more likely than the general population to have hypertension and that only UC was independently associated.

There is a lot of new information about the link between various malignancies and inflammatory bowel disease. Here: answers to 3 key questions.

Diet diaries and food frequency questionnaires are both effective tools to capture important patterns between food items and symptoms of IBD.

IDA is commonly seen in IBD as a result of iron malabsorption and, ironically, chronic blood loss through disrupted mucosal surfaces.

Patients with UC who also have celiac disease may be at higher risk for pancolitis as opposed to more limited forms of inflammatory bowel disease.

The mechanisms and effectiveness of probiotics in treatment of irritable bowel syndrome and inflammatory bowel disease are emerging.

New insights into how clinicians might approach treatment for patients with IBD highlighted the recent Crohn’s & Colitis Foundation’s Clinical & Research Conference.

New drugs are needed because a significant fraction of patients reach the end of the line with existing therapies.

All patients with IBD should receive aggressive ongoing assessment of their inflammatory state and its response to immunomodulators, anti-TNF drugs, and other agents.

A purely dichotomous understanding of whether to start treatment for patients who have IBD with anti-TNF agents is becoming an outdated view.

Even the most experienced and skilled gastroenterologists in the country are struggling to make science-based decisions in this area.

A straightforward discussion drove toward attendees toward the more current understanding of the clinical and genetic overlap between the 2 major forms of IBD.

They are similar chronic inflammatory diseases with causes unknown, and recent clinical and genetic evidence supports an intertwined pathogenic relationship.

Patients with ulcerative colitis and Crohn’s disease typically don’t receive preventive services at the same rate as general medical patients. Vaccination is a key area of confusion.

The location (pretibial surface) of this ulcer, its visibly rolled undermined border, and severe pain are all typical of pyoderma gangrenosum, which is typically associated with inflammatory bowel disease, rheumatoid arthritis, and hematologic malignancies.

Is the increased risk of IBD due to pollution, a too-clean home, or antibiotics? Or none of the above?

An association between non-steroidal anti-inflammatory drugs and these two inflammatory bowel disorders has long been suspected but not, until now, documented.

Patients with IBD may have discomfort for 3 to 5 years before a diagnosis is made. Many are treated unsuccessfully with antibiotics, anti-spasmodics, or narcotics. Here, read 5 important tips, plus a bonus point, to help streamline diagnosis and management.

Like other chronic inflammatory conditions, inflammatory bowel disease (IBD) has been revolutionized by the advent of biologic agents that fundamentally alter the inappropriate inflammatory response. The most potent of these are the biologic agents, infliximab, adalimumab, certolizumab pegol, and natalizumab. They also have the most dangerous side-effect profile.

Are persons with asthma at risk for other proinflammatory disorders? Yes, say researchers from the Mayo Clinic and Olmsted Medical Center in Rochester, Minn, who found that asthma is associated with the development of diabetes mellitus and coronary artery disease. However, there was no association between asthma and rheumatoid arthritis or inflammatory bowel disease.