Endocrinology

The proportion of adults with diabetes and obesity in the US increased from 1999 to 2020, though more adults achieved blood pressure and lipid control during the same period.

The beneficial effects of SGLT-2 inhibitors in reducing CV death and heart failure hospitalization in patients with T2D are related to body weight, suggest new data.

The 6 obesity care organizations are collaborating to overcome the roadblocks to effective and equitable treatment for the ubiquitous, chronic, and deadly disease.

Risk of T2D was reduced by 49% over a 10-year follow up period among study participants who followed a vigorous or moderate exercise plan vs those who did not engage in exercise.

The DASH diet, Mediterranean diet, and Flexitarian diet top the list of 10 best diets for persons with diabetes as ranked by US News and World Report.

Your daily dose of clinical news you may have missed.

Your daily dose of clinical news you may have missed.

Sustained weight loss with semaglutide 2.4 mg is a result of the drug's effects on control of eating, including reduced cravings and hunger and increased satiety, study authors write.

Your daily dose of clinical news you may have missed.

Bexagliflozin significantly improved glycemic control in adults when used as monotherapy, in combination with metformin, or when added to several SOC regimens.

Adults with T2D may be able to reduce their liver fat and improve their liver fibrosis stage with reductions in HbA1c, according to findings from a retrospective analysis.

Investigators report a 30% reduced risk of total joint replacement in persons with type 2 diabetes treated with metformin vs those who did not receive the drug.

An overall good quality of diet and higher fish intake during pregnancy were related to better language skills in 2-year-old children, according to new study.

Australian investigators found a 14% higher risk of fracture for every 1-SD increment in level of HDL-C in community dwelling healthy adults aged ≥70 years.

The update removes a previous limitation that stated semaglutide should not be used as an initial therapy for treating patients with T2D.

The 13 Key Action Steps in the AAP's landmark obesity guidelines reflect more than a decade of research on evaluation and treatment of the disease in children and adolescents.

Diabetes cases in the US among those younger than age 20 years, if left unchecked, are projected to increase by more than 600% by 2060, according to new projections.

Adolescents with more positive psychological assets were more likely to have good cardiometabolic health 2 decades later, and associations were stronger for Black youth.

A global prevalence of osteoporosis among persons with T2D of more than 25% calls for greater focus on screening for and managing the bone loss disease in this population.

The in-person requirement for mifepristone dispensing was removed from the drug's REMS, potentially expanding access to women in need in a precarious environment.

Find a compact sampling of 2022 research on type 2 diabetes and its treatment reviewed on Patient Care, chosen by the editorial staff.

About one-quarter of children with T2D are not obese, according to a meta-analysis, making comprehensive screening essential in the population.

The Dexcom G7 continuous glucose monitoring system provides an overall MARD of 8.2%, the highest of any FDA-cleared CGM, the company says.

Empagliflozin is the first SGLT-2 inhibitor to demonstrate a statistically significant reduction in HbA1c in children and adolescents with type 2 diabetes.

Findings from a new study suggest that supplementing standard care for obesity with butyrate helped reduce BMI, improve glucose metabolism, and reduce inflammation markers.

An obesity specialist explains why clinicians should start at the root cause when managing patients with type 2 diabetes and obesity.

The "Plan B" emergency contraceptive at 2 times the normal dose was not more effective in study participants with BMI >30.

Teplizumab, an anti-CD3 monoclonal antibody, delayed the median onset of stage 3 T1D by approximately 2 years compared to placebo in a pivotal clinical trial.

Ordering an obesity phenotype should be as simple and routine as ordering an HbA1c or a lipid panel, says obesity expert Andres Acosta, MD, PhD.

Mayo Clinic's Andres Acosta, MD, PhD, details the 4 biologic obesity phenotypes his team has identified and how their use can change weight loss outcomes.