February 21st 2025
Comorbid conditions accrued at a rate 30% faster among adults with depression than in those without the disorder over a 7-year follow-up period.
February 10th 2025
AV-101 is an orally bioavailable small molecule NMDA receptor antagonist with antinociceptive effects similar to gabapentin but with more a more favorable safety profile.
February 6th 2025
People with MDD demonstrated a preference for carbohydrate-rich foods and reduced reward from fat- and protein-rich foods, according to new research.
February 4th 2025
GH001, an inhalable 5-MeO-DMT therapy, led to a -15.5 MADRS score reduction by day 8 in patients with treatment-resistant depression.
January 31st 2025
Your daily dose of the clinical news you may have missed.
Perception of MDD in the Healthcare Community
Experts in psychiatry share their thoughts on the perception of MDD within the healthcare community and the implications of this condition being viewed as chronic vs episodic.
Depression and Comorbid Health Conditions
Carmen Kosicek, MSN, PMHNP-BC, and Charles Montano, MD, comment on the interplay between depression and other comorbid psychiatric and medical health conditions as well as the economic impact of MDD.
Impact of MDD Episode Duration and Recurrences
Charles Montano, MD; Carmen Kosicek, MSN, PMHNP-BC; and Gus Alva, MD, DFAPA, review the impact of the duration of MDD episodes and goals of managing episode recurrences.
US Mental Health Crisis Meets Limited Treatment Capacity: APA Survey Findings
While 60% of US psychologists have no openings for new patients, demand for treatment continues to rise, especially among adolescents and health care workers.
All Health Care Professionals Can Support One Another's Mental Health, Expert Says
Not every physician has to be a mental health expert to assist their colleagues, staff, and patients in improving their mental well-being. Just start the conversation.
USPSTF Issues Final Recommendations for Anxiety, Depression Screening in Youth
For the first time, the task force recommended screening children aged 8 and older for anxiety in primary care settings.
Physician Wellbeing: Current State & Solutions to Improve It
There was no change in physician burnout in the past year and it remains significantly higher than pre-pandemic times, according to a new nationwide survey.
4 New Drugs Approved for Primary Care: Q3 2022
Novel NMDA receptor antagonist approved for the treatment of major depressive disorder, first topical PDE4i approved for plaque psoriasis, and more.
Current Telehealth Use 88% More Likely by Patients with Chronic Conditions: Survey
Telehealth continues to support continuity of care and to increase access to and willingness to use the health care system, according to survey authors.
CDC: Suicide Rate Up in 2021, Youth and Young Adults at Greatest Risk
The numbers drive up concern but do not provide context for this very complex issue, according to the American Foundation for Suicide Prevention.
Mental Health Treatment Utilization in America: 5 Findings from National Center for Health Statistics Report
The percentage of adults who received any mental health treatment increased, women were more likely than men to receive treatment, and 3 more key findings.
USPSTF: Primary Care Clinicians Should Screen Adults for Anxiety, Depression
USPSTF's draft statement is the first it has issued recommending primary care screening for adults younger than 65 who do not have signs or symptoms of anxiety or depression.
Novel Rapid-acting Treatment for Major Depressive Disorder First to Get FDA Nod
The dextromethorphan HBr-bupropion HCI combination uses the first new oral MOA in 6 decades and is labeled to improve depressive symptoms starting at 1 week.
Behavioral Health Integration in Primary Care is Essential: Call to Action from Leading Physician Groups
The ACP and AAFP along with 6 other professional groups say the current system is failing US mental health needs and it's time to make changes.
US Cardiovascular Health Remains Poor, Declines Begin in Early Childhood: American Heart Association Investigators
US CV health is well below ideal, with 80% of adults scoring as only low or moderate in the first published study using AHA's new Life's Essential 8 algorithm.
Women Found "Significantly" More Likely to Experience Long COVID, Disaggregated Research is Essential, Investigators Say
A literature review comprising ~1.3 million patients infected with SARS-CoV-2 reveals women are 22% more likely vs men to develop long COVID, yet treatment is no different.
Obesity and Depression in Adolescents: Understanding the Interplay
Understanding the interplay between obesity and depression in children is key for clinicians to best advise this patient population. An overview, here.
COVID-19: Half of US Adults Don't Feel "Back to Normal” Yet
Most adults continue to mask indoors in public places and still limit their pre-pandemic activities.
Depression Following Myocardial Infarction Raises Stroke Risk in US Adults
ACC 2022. Large study of US adults showed those with depression following MI were 50% more likely to experience a stroke than those who did not have depression.
Benefits of Exercise in CVD Risk Reduction More than Double in Anxiety, Depression
ACC 2022. Exercise lowers CVD risk in part by reducing the same neurobiologic activity associated with depression and anxiety, according to study authors.
Where are US Youth at Greatest Risk and Why? States Ranked on 6 Key Indicators
The highest percentage of youth without a high school diploma is in New Mexico and the youth poverty rate is highest in DC. More red flag indicators follow.
Mental Disorders Still a Burden on Global Health, According to New Analysis
The prevalence of mental disorders has been rising globally and the conditions today remain a leading cause of disease burden worldwide, found 30-year systemic analysis.
Two-thirds of Americans with Mental Illness Support Use of Psychedelics, Survey Finds
Americans with anxiety, depression, and PTSD would be willing to try ketamine, psilocybin, and MDMA if they worked better than traditional medications, a Harris Poll finds.
Pandemic-induced Sleep Disturbance Affects More than Half of US Adults
"COVID-somnia," defined as a group of chronic sleep disturbances, has made adequate rest elusive for millions, including health care first responders.
The "Lorna Breen Act" in Short
Click through a short summary of the provisions of the Dr Lorna Breen Health Care Provider Protection Act.
Dr Lorna Breen Health Care Provider Protection Act Passed by Senate in Unanimous Vote
The first-of-its-kind legislation would authorize $35 million for programs aimed at practitioner mental health education and campaigns to support seeking help.
Loneliness in Aging Adults Associated with High-risk Medication Use
Older adults who report being "highly lonely" are up to 2.5 times more likely to use opioid analgesics, sedatives, and anxiolytics.
Study Emphasizes Primary Care’s Crucial Role in Combatting COVID-19-related Mental Illness
Compared to psychiatrists and subspecialists, the proportion of visits to primary care was higher for patients with depression or anxiety and any mental illness in a new cross-sectional study.
Improved Outcomes Seen with Regular Antidepressant Use in Patients with Diabetes and Depression
Antidepressant therapy, used as prescribed, reduced risk for advanced complications of diabetes and death among more than 36 000 patients with comorbid diabetes and depression.
COVID-19 Pandemic Took a Huge Toll on Physician Mental Health
The COVID-19 pandemic has sorely challenged the emotional well being of all healthcare providers. Here, a look back is followed by a guide to moving forward.