Editor of Patient Care Online.
Ozempic Approval Expanded to Include Patients with T2D and CKD: Daily Dose
Your daily dose of the clinical news you may have missed.
Postnatal Antibiotics for Maternal Indications May Heighten Childhood Asthma Risk
AAAAI 2025. Early postnatal antibiotic exposure in full-term infants was associated with a 30% increased risk of childhood asthma, according to a new study.
AAAAI 2025: Omalizumab Shows Favorable Outcomes Versus Oral Immunotherapy in Multi‐Food Allergy Treatment
In a randomized clinical trial, omalizumab achieved a 36% treatment success rate for multi-food allergy compared with 19% for oral immunotherapy.
Investigational Nonopioid Beats Placebo in Phase 3 Trial: Daily Dose
Investigational Cell Therapy Cuts Insulin Dependency in Late-Stage Type 2 Diabetes
CELZ-201 reduced insulin dependency and stabilized HbA1c in 1-year follow-up data from a pilot study in T2D.
New Biomarkers Identified for Early Detection of Alzheimer Disease
Phospho-tau serine-262 and serine-356 were identified as biomarkers for early Alzheimer disease detection in a new study published in Nature Medicine.
Heart Disease Remains Leading Cause of Death in US: Daily Dose
FDA Grants Fast Track Designation to Rezpegaldesleukin for Atopic Dermatitis
Rezpegaldesleukin targets the IL-2 receptor complex to stimulate regulatory T cells, aiming to restore immune balance in people with atopic dermatitis.
Elevated Suicide Risk Identified in People with Headache Disorders
Post-traumatic headaches and trigeminal autonomic cephalalgia significantly increased the risk for attempted and completed suicide, according to new study.
FDA Approves Nonopioid Journavx for Acute Pain: Daily Dose
FDA Approves AbbVie's Combination Antibiotic Emblaveo for Complicated Intra-Abdominal Infections
The novel therapy combines aztreonam, a monobactam antibiotic, and avibactam, a β-lactamase inhibitor.
Nasal COVID-19 Vaccine Poised to Enter Phase 1 US Clinical Trial
The study will assess the safety and efficacy of a next-generation COVID-19 vaccine via nasal spray and inhalation.
US Dementia Cases to Double by 2060: Daily Dose
Colorectal Cancer: How a New Blood-Based DNA Test Stacks Up in Screening Options
William Grady, MD, coauthor of the ECLIPSE trial, discusses how the Shield cfDNA blood-based test compares to traditional CRC screening methods.
FDA Approves New Wearable Treatment for Parkinson Disease
Onapgo is the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in people with advanced Parkinson disease.
New Study Links Major Depressive Disorder to Specific Changes in Eating Preferences
People with MDD demonstrated a preference for carbohydrate-rich foods and reduced reward from fat- and protein-rich foods, according to new research.
FDA Greenlights Symbravo for Acute Treatment of Migraine: Daily Dose
Investigators Identify Hemoglobin A1c/HDL-C as a Predictor of Stroke Risk in Older Adults
Elevated HbA1c/HDL-C ratios significantly increased stroke risk, even after adjusting for confounding factors, reported authors of a recent study.
Roche Receives FDA 510(k) Clearance for First US Blood Test Measuring Lp(a) in Molar Units
The Tina-quant® Lipoprotein (a) Gen.2 Molarity assay measures Lp(a) in molar units, providing a more accurate particle-based risk assessment than mass units.
Study Identifies Key Symptoms of Topical Steroid Withdrawal: Daily Dose
MindMed Initiates Second Phase 3 Trial of Psychedelic MM120 for Generalized Anxiety Disorder
The first patient was dosed in the Panorama study assessing MM120 ODT, a form of LSD, for the treatment of GAD.
AI-Assisted Mammography Boosts Breast Cancer Detection by 29% in Large Study
Results from the MASAI clinical trial also showed that AI-assisted screening reduced screen-reading workload without increasing the rate of false-positives.
Colorectal Cancer Screening: Considerations for Using Cell-Free DNA Blood Tests in Older Adults
William Grady, MD, coauthor of the ECLIPSE study, discusses the use of non-invasive cfDNA blood-based tests for CRC screening in older adults.
FDA Approves Monthly Lecanemab for Early-Stage Alzheimer Disease: Daily Dose
Optimizing PTSD Treatment: The Role of Brexpiprazole and Sertraline in Future Guidelines
Brexpiprazole and sertraline showed promise for PTSD treatment in a recent study. Lead author, Lori Davis, MD, discusses clinical findings, treatment guidelines, and future research directions.
COVID-19 Associated with Higher Long-Term Mortality Than Flu or RSV: New Data
Researchers found that COVID-19 had a higher long-term mortality than influenza and RSV in veterans—underscoring vaccination’s vital role.
Effectiveness of Anti-Obesity Drugs for CVD Prevention: A Clinician Discussion
Anila Chadha, MD, talks to Patient Care about how antiobesity medications can aid in reducing CVD risk in patients with obesity.
Counseling Patients on False Positives in cfDNA Blood-Based Colorectal Cancer Screening
William Grady, MD, highlights ongoing efforts to improve test sensitivity and developments of new blood-based tests for early detection of CRC.
Stool Tests Still Top Choice for CRC Screening: Daily Dose
Vaccine Distrust, Emboldened During the Pandemic, Runs Deep: An Expert Perspective
Robert Hopkins, Jr, MD, says of official communications during the COVID-19 pandemic that not enough was explained to the public about policy shifts, leaving people wondering.
