- Clinical Technology
- Adult Immunization
- Hepatology
- Pediatric Immunization
- Screening
- Psychiatry
- Allergy
- Women's Health
- Cardiology
- Pediatrics
- Dermatology
- Endocrinology
- Pain Management
- Gastroenterology
- Infectious Disease
- Obesity Medicine
- Rheumatology
- Nephrology
- Neurology
- Pulmonology
A Young Child with a Devastating Facial Lesion
What disease, known in antiquity but largely eradicated from the developed world, caused this severe facial scarring?
An undernourished child presents with a facial lesion present for some months (Figure). The problem started as a gingival ulcer with facial edema and progressed to a necrotic black escar. After sloughing of the escar and the external cheek skin, the area finally healed with a scar and retraction over the course of the next weeks.
What is the most likely diagnosis?
Kymera's Oral STAT6 Degrader KT-621 Shows Biologic-Like Activity in Early Atopic Dermatitis Trial
December 8th 2025KT-621 achieved deep STAT6 degradation and strong 4-week EASI and itch reductions, offering a potential new oral option for moderate–severe AD and other Th2 inflammation-driven disease.
