Concerned about the yellow plaque on his upper eyelid, a 45-year-old man sought medical evaluation. The slow-growing, asymptomatic lesion had developed several months earlier.
Concerned about the yellow plaque on his upper eyelid, a 45-year-old man sought medical evaluation. The slow-growing, asymptomatic lesion had developed several months earlier.
Dr Raymond Kuwahara of Memphis diagnosed xanthoma palpebrarum, or xanthelasma, the most common type of xanthoma. Eyelid xanthomas are usually found in older adults; in younger persons, the condition may be associated with familial hypercholesterolemia or familial dyslipoproteinemia. This patient had normal lipid levels and no family history of lipid anomalies.
Referral to a dermatologist is recommended. Xanthoma palpebrarum may be surgically excised or chemically treated with phenol or trichloracetic acid.
Research That Is Changing Endocrinology: Advances, Challenges, and The Future, with Irl B Hirsch, MD
April 3rd 2025ACP 2025: Irl B Hirsch, MD, reviewed findings from 8 papers published in 2024 that he believes have made or will make a difference in the practice or understanding of the clinical area.