This 14-year-old boy presented with slowly progressive hypopigmented lesions that had been present on the lower extremities for the previous 2 years.
This 14-year-old boy presented with slowly progressive hypopigmented lesions that had been present on the lower extremities for the previous 2 years.
This is vitiligo, a common acquired or heritable melanocytopenic disorder characterized by progressive, sharply demarcated, cutaneous white macules. Preferred sites are the face, anterior tibial area, hands, feet, elbows, upper chest, and low back. Vitiligo is more prevalent in persons with hyperthyroidism, adrenal insufficiency, pernicious anemia, and diabetes mellitus.
The course of vitiligo is variable. Some lesions may remit spontaneously while others are developing, but relentlessly progressive depigmentation may also occur.
Sotagliflozin in Patients with Type 1 Diabetes and CKD to be Discussed at October FDA AdComm Meeting
October 14th 2024Lexicon's sotagliflozin is on the October 31 docket for discussion by the FDA's Endocrinologic and Metabolic Drugs Advisory Committee; PDUFA goal date remains set for December 20.