The seasonal respiratory syncytial virus, which claims between 6000 and 10 000 older adult lives each year, will now face significant barriers to spread in this vulnerable population the US.
The short slide show that follows provides snapshots of the headline news stories posted on Patient Care® in 2023 that traced the clinical trials and approval process for GKS's RSVPreF3 (Arexvy) and Pfizer's RSVPreF (Abrysvo).
In 2023, after more than 50 years of research to create the antigen that would safely elicit the most robust immune response to the virus, 2 pharmaceutical companies, within a month of each other, were granted US Food and Drug Administration approval for a vaccines against the virus: GSK for in for RSVPreF3 (Arexvy) and Pfizer for RSVPreF (Abrysvo). Both are indicated for adults aged 60 years and older based on shared decision making with their health care provider. The CDC strongly recommends a single shot for older adults with certain chronic conditions that put them at high risk for severe disease.