Patients often present with skin lesions that are suggestive of skin cancer. Is it or isn’t it? This week’s photo quiz tests your knowledge of several possible cancerous presentations.
Question 1:
A 72-year-old man complained about an asymptomatic, gradually expanding “spot” on his forehead.

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Question 2:
A 7-year-old African American girl presented with an asymptomatic gray lesion beneath her right eye that had appeared before her first birthday. She was a healthy child with macular gray discoloration on the right infraorbital skin. There was no abnormal pigment noted on the conjunctiva. She had nevus of Ota, also called oculodermal melanosis.

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Question 3:
A 61-year-old obese, man with type 2 diabetes presented with the gradual onset of a mildly tender lesion on the dorsum of the right arm. He had a well-known history of actinic keratoses and multiple nonmelanoma skin cancers.

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Question 4:
A 6-year-old boy had “redness and pain” of skin on his left upper abdomen. Physical examination revealed a large cluster of vesicles with underlying erythema and mild warmth. The lesion, present for 5 years, had been diagnosed as lymphangioma circumscriptum.

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Question 5:
An 82-year-old man complained about an asymptomatic “spot” on his chest within which a darker area had recently developed. Physical examination revealed a large pigmented macule on the right upper chest. A darker area was eccentrically placed within the larger lesion. A biopsy revealed lentigo maligna melanoma, in-situ.

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ANSWER KEY:
Question 1. Answer: d
Question 2. Answer: e
Question 3. Answer: a
Question 4. Answer: c
Question 5. Answer: b
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