- Clinical Technology
- Adult Immunization
- Hepatology
- Pediatric Immunization
- Screening
- Psychiatry
- Allergy
- Women's Health
- Cardiology
- Pediatrics
- Dermatology
- Endocrinology
- Pain Management
- Gastroenterology
- Infectious Disease
- Obesity Medicine
- Rheumatology
- Nephrology
- Neurology
- Pulmonology
Subtle Stridor: Seen in the ED
Brady Pregerson, MD
History of present illness. A teenager is brought to the emergency department by his parents for 2-3 months of progressive shortness of breath following an admission to the ICU after a bad car crash. At that time he had multiple rib fractures, a pneumothorax and a splenic laceration. His mom says his breathing is “noisy” at times, especially when he exerts himself or is talking a lot.
Vital signs and physical examination. Vital signs and pulse oximeter reading were normal. There was very subtle stridor while talking. Oral and pulmonary exams were otherwise unremarkable.
Initial diagnostic testing:
- Findings on basic laboratory studies all normal
- Chest X-ray showed healed rib fractures but was otherwise normal
- Neck X-ray image shown here
What is the most accurate diagnosis?
Roche, Alnylam Advance Zilebesiran Into Phase 3 CV Outcomes Trial for Resistant Hypertension
September 9th 2025Zilebesiran’s twice-yearly dosing and sustained BP reductions could offer a new therapeutic approach for adults with resistant hypertension and high CV risk who are uncontrolled on current SOC regimens.
