Mottled skin; neuropathic pain; syncope . . . test yourself on these and other subjects.

Question 1:
These lesions appeared “overnight” on the leg of a 66-year-old black woman who was caring for her mother who had been hospitalized.
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Question 2:
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Question 3:
Familial adenomatous polyposis was diagnosed in a 26-year-old man whose father and grandfather had colon cancer when they were in their 40s.
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Question 4:
Brugada syndrome was diagnosed in a 15-year-old boy after a syncopal episode experienced when he was playing football.
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Question 5:
A 54-year-old man had acute onset of a painful scrotal rash.
ANSWER KEY »
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ANSWER KEY:
Question 1. B
Question 2. A
Question 3. F
Question 4. E
Question 5. D
FDA Approves Updated Indication Statement for Upadacitinib in Inflammatory Bowel Disease Treatment
October 14th 2025FDA approves updated indication for upadacitinib in ulcerative colitis and Crohn disease treatment, allowing use after one systemic therapy when TNF blockers are clinically inadvisable.