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Show Patients That Hypertension is a Pressing Matter
To demonstrate to hypertensive patientsthe effect of high blood pressureon the heart, have them wrap onehand around a partially inflated sphygmomanometercuff and close thevalve.
To demonstrate to hypertensive patientsthe effect of high blood pressureon the heart, have them wrap onehand around a partially inflated sphygmomanometercuff and close thevalve. Ask them to squeeze the cuff(at a rate of 1 squeeze per second)until the mercury column reachestheir systolic blood pressure. Explainthat this is how hard their heart ispumping. Then, to show how this compareswith a healthy heart, ask themto squeeze the cuff to 120 mm Hg. Theeffect is most dramatic for patientswith moderate to severe hypertension.
-- Rex H. Wu, MD
New York
Roche, Alnylam Advance Zilebesiran Into Phase 3 CV Outcomes Trial for Resistant Hypertension
September 9th 2025Zilebesiran’s twice-yearly dosing and sustained BP reductions could offer a new therapeutic approach for adults with resistant hypertension and high CV risk who are uncontrolled on current SOC regimens.
