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Sacral Dimple
The parents of an 18-month-old girl were curious about a depressed area on their daughter's lower back, which had been present at birth. The child was otherwise healthy.
The parents of an 18-month-old girl were curious about a depressed area on their daughter's lower back, which had been present at birth. The child was otherwise healthy.
Drs Alexander K. C. Leung and Justine H. S. Fong of Calgary, Alberta, made the diagnosis of sacral dimple. It is thought that a skin dimple develops in utero as a result of interposition of tissue between a sharp, bony point and the uterine wall; this leads to decreased subcutaneous tissue formation.
A sacral dimple is usually benign. However, it may herald an underlying developmental defect, such as spina bifida occulta and diastomyelia. A sacral dimple may be associated with several hereditary disorders, including Bloom; Smith-Lemli-Opitz; and 4p, or Wolf-Hirschhorn, syndromes.
Lebrikizumab Demonstrates Efficacy, Safety in Patients With Skin of Color With AD
June 11th 2025RAD 2025. Lebrikizumab improved skin clearance, itch, and pigmentation in patients with skin of color and atopic dermatitis, with strong safety data through 24 weeks, according to late-breaking data.
