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Risk of CKD Progression Lower in Women vs Men: Findings from the CRIC Study
Authors of the CRIC study found sex-related disparities in chronic kidney disease progression. Scroll through our slideshow to get the highlights.
Men in the US have a higher incidence of end stage renal disease (ESRD), despite a lower incidence of chronic kidney disease (CKD) vs women. Men may have more rapid progression of CKD vs women, though findings from previous studies have been inconsistent. Now, results of a large, prospective investigation show that women with CKD have a significantly lower risk of developing ESRD, 50% eGFR decline, progression to CKD stage 5, and death vs men. Taken together, the findings of this study by Ricardo and colleagues suggest a sex-related disparity in CKD progression and mortality, though additional studies are needed to pinpoint the factors underlying the sex-related differences.
Sotagliflozin in Patients with Type 1 Diabetes and CKD to be Discussed at October FDA AdComm Meeting
October 14th 2024Lexicon's sotagliflozin is on the October 31 docket for discussion by the FDA's Endocrinologic and Metabolic Drugs Advisory Committee; PDUFA goal date remains set for December 20.
