For resistant pruritus ani, have patients try using cholestyramine topically.
For resistant pruritus ani, have patients try using cholestyramine topically. In addition to binding cholesterol and bile salts in the gut, cholestyramine binds bile salts from stool, which can irritate perianal skin. Have the pharmacist compound it with a preservative-free emollient ointment at a strength of 6% to 10%.
---- Richard A. Honaker, MD
Carrollton, Tex
Oral PCSK9 Inhibitor Enlicitide Meets All End Points in Phase 3 Hypercholesterolemia Trial
September 2nd 2025At week 24, patients receiving once-daily enlicitide demonstrated statistically significant and clinically meaningful reductions in low-density lipoprotein cholesterol compared with placebo.