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No-Sweat Antidepressant Therapy?
I have a patient who has taken escitalopram for a number of years, and he complains of increased sweating, particularly during the summer. Are SSRIs associated with hyperhidrosis? Would it be worthwhile to switch to a different SSRI?
I have a patient who has taken escitalopram for a number of years, and he complains of increased sweating, particularly during the summer. Are SSRIs associated with hyperhidrosis? Would it be worthwhile to switch to a different SSRI?
----- Donna Jackson, MSN, APRN
Cornwall, NY
Between 10% and 20% of patients who take SSRIs may experience troubling hyperhidrosis.1 I am unaware that any particular SSRI is more likely than others to produce this effect. Benztropine mesylate taken in conjunction with the SSRI may ameliorate the excessive sweating.
----- Lewis P. Stolman, MD
Associate Clinical Professor of Pediatrics and Dermatology
New Jersey Medical School
University of Medicine and Dentistry of New Jersey
Newark
References:
REFERENCE:
1.
International Hyperhidrosis Society. Sweat and anti-depressants: what you need to know. Available at:
http://www.sweathelp.org/English/CMN_Article.asp?ArticleCode=81572853&EditionCode=87373635
. Accessed March 26, 2008.
Podcast: Arthritis, Anxiety, and Depression: Managing a Common Comorbidity
May 14th 2012Anxiety is even more common than depression among people who have arthritis, a new study has shown. Here to discuss the implications for diagnosis and treatment is Eilzabeth Lin MD, a family medicine physician who is a longstanding researcher in the field of depression and pain.
FDA Approves Esketamine as Monotherapy for Adults With Treatment-Resistant Depression
January 21st 2025The approval of esketamine follows an FDA Priority Review and is based on data showing that esketamine alone demonstrated rapid and superior improvement in depressive symptoms compared with placebo.
